Cardiac Myxoma: Fourteen-Year Experience of a Tertiary Reference Center

Year 2017, Volume: 20 Issue: 3, 210 - 216, 03.12.2017

Yiğit Çanga , Mehmet Baran Karataş Ali Nazmi Çalık Tahir Bezgin Veysel Ozan Tanık Ufuk Yıldız Emir Renda Tolga Sinan Güvenç Can Yücel Karabay Ömer Kozan

Abstract

Introduction:
Myxoma
is the most common primary cardiac tumor, which is frequently diagnosed between
the ages of 30-60 years. Myxomas are encountered more frequently in women. They
are mostly located in the left atrium. In this retrospective study, we observed
demographic, clinical, pathological, and echocardiographic findings of myxomas.
In addition to short and long term follow-up result of patients having myxoma,
we researched the risk factors of patients who presented with embolism as a
complication of myxoma. Also we researched the risk factors of the patients who
represented with embolism.

Patients
and Methods: In this retrospective study, we searched the database of
our hospital using the keyword “myxoma” between March 2001 and January 2015.
Sixty-six patients, whose cardiac tumors were resected and confirmed as myxoma
after pathologic evaluation, were included in this study.

Results: The mean
age of our surgically treated patients was 55 ± 12.3 years. Forty (% 60.6) of
them were female, and the most common presented symptom was dyspnea. An embolic
event was noted in %19.7 of patients. Myxomas were mostly located in the left
atrium. A total of 4 (%6) patients showed tumor recurrence, and only one patient
died during the follow-up. As the patients were compared regarding embolic
phenomenon, male gender, location at the roof of the left atrium, and irregular
surface characteristics were more frequently associated with embolism.

Conclusion: Contrary to previous
studies, in our study, thromboembolic events as an important complication of
myxomas was associated with male gender and location at the roof of the left
atrium. However, in accordance with other studies, type 1 myxomas were
significantly more prevalent in our patients with the diagnosis of embolism.

Keywords

Myxoma, embolism, echocardiography

Kardiyak Miksoma: Tersiyer Bir Referans Merkezinin 14 Yıllık Deneyimi

Abstract

Giriş: Miksomalar sıklıkla 30 ile 60 yaş aralığında tanı alan en sık görülen
primer kardiyak tümörlerdir. Miksomalar kadınlarda daha sık görülür. En sık
olarak sol atriyum yerleşimlidirler. Biz retrospektif tek merkezli bu
çalışmamızda miksomaların demografik, klinik, patolojik ve ekokardiyografik
özellikler ile birlikte kısa ve uzun dönem sonuçlarını sunduk. Ayrıca emboli
kliniği ile başvuran miksoma hastalarındaki risk faktörlerini araştırdık.

Hastalar ve
Yöntem: Retrospektif tanımlayıcı nitelikteki bu araştırmada
üçüncü basamak eğitim ve araştırma hastanemizin veritabanında cerrahi
epikrizleri Mart 2001-Ocak 2015 tarih aralığında ‘‘miksoma’’ anahtar kelimesi
ile tarandı. Cerrahi olarak rezeke edilmiş ve patolojik olarak kesin tanısı konmuş
olan 66 hasta çalışmamıza dahil edildi.

Bulgular: Miksoma tanısıyla elektif cerrahi uygulanan hastalarımızın ortalama yaşları
55 ± 12.3 yıl idi. Kırk (%60.6) hasta kadın cinsiyetindeydi. En sık görülen
semptom dispneydi. Hastaların %19.7’sinde geçirilmiş bir emboli atağı mevcuttu.
Miksomalar en sık sol atriyumdan köken almaktaydı. Takip süresince 4 (%6)
hastada nüks, sadece bir hastada ölüm görüldü. Emboli geçiren ve geçirmeyen
gruplar kıyaslandığında emboli geçiren grupta erkek cinsiyet, sol atriyum çatısında
yerleşim ve irregüler yüzey istatistiksel anlamlı olarak daha fazla saptandı.

Sonuç: Bizim çalışmamızda,
miksomaların önemli bir komplikasyonu olan embolik olaylar, önceki
çalışmalardan farklı olarak erkek cinsiyet ve sol atriyum çatısından köken alan
miksomalar ile ilişkili bulunmuştur.  Tip
1 miksomalar da diğer çalışmalar ile benzer şekilde emboli tanısı olan
hastalarımızda anlamlı derecede daha fazla saptanmıştır.

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