SARS-COV-2, İNFLUENZA VE RESPİRATUAR SİNSİTYAL VİRÜS PNÖMONİLERİ NEDENİYLE HASTANEDE YATAN HASTALARIN KLİNİK ÖZELLİKLERİNİN KARŞILAŞTIRILMASI

Year 2024, , 63 - 69, 17.01.2024

Gülbahar Darılmaz Yüce , Matin Iskandarov , Cemre Gündüz , Yaşar Ozan Saraçoğlu , Buğra Hatipoğlu , Cemile Cansu Alperen , Tuğba Yanık Yalçın , Tülin Yıldırım , Meriç Çolak , Gaye Ulubay , M. Şule Akçay

https://doi.org/10.18229/kocatepetip.1192685

Abstract

AMAÇ: İnfluenza, respiratuar sinsityal virüs (RSV) ve şiddetli akut solunum yolu sendromu koronavirüs-2 (SARS-CoV-2) enfeksiyonu damlacıklar yoluyla yayılan, benzer semptom ve radyolojik bulguları olan ve solunum yetmezliğine neden olabilen etkenlerdir. Bu çalışma yeni koronavirüs hastalığı (COVID-19), influenza ve RSV pnömonisi olan hastaların klinik özelliklerini ve mortalite oranlarını karşılaştırmak için yapılmıştır.
GEREÇ VE YÖNTEM: Başkent Üniversitesi Tıp Fakültesi Hastanesi'nde COVID-19, influenza ve RSV pnömonisi nedeniyle yatırılan toplam 182 hasta çalışmaya dahil edildi. Hastalar klinik durumlarına göre gruplandırıldı. Hastaların demografik özellikleri, komorbiditeleri, laboratuvar ve radyolojik bulguları, solunum destek tedavileri ve mortalite oranları kaydedildi ve gruplar arasında karşılaştırıldı.
BULGULAR: Ortalama yaş COVID-19 grubunda (n:115) 69.4±7 yıl, influenza grubunda (n:33) 72,9±17,1 yıl ve RSV grubunda (n:34) 66,5±22,4 yıl idi. Gruplar arasında yaş farkı yoktu (p=0,305). COVID-19 grubunda erkek hastaların hastane yatış oranı daha fazlaydı (p=0,036). Komorbiditeler açısından gruplar arasında fark yoktu (p>0.05). COVID-19, RSV ve influenza hasta grupları arasında mortalite oranları açısından fark yoktu (p=0.260).
SONUÇ: Pulmoner tutulumlu viral enfeksiyonlar kötü klinik seyir gösterebildikleri için özel dikkat gerektirirler. İçinde bulunduğumuz yüzyılda ölümlere neden olan COVID-19 pnömonisinin klinik seyrinin şiddeti, influenza ve RSV gibi viral enfeksiyonların klinik seyrinden farklı değildir.

Keywords

COVID-19, İnfluenza, Pnömoni, Solunum sinsityal virüsü

Supporting Institution

Bu çalışma Başkent Üniversitesi Araştırma Fonu tarafınca desteklenmiştir.

Project Number

KA20/452 – Tarih:15/12/2020

COMPARISON OF CLINICAL CHARACTERISTICS OF PATIENTS HOSPITALIZED DUE TO SARS-COV-2, INFLUENZA AND RESPIRATORY SYNCYTIAL VIRUS PNEUMONIA

Abstract

OBJECTIVE: Influenza, respiratory syncytial virus (RSV), and severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection are agents that spread through droplets, have similar symptoms and radiological findings, and can cause respiratory failure. This study was conducted to compare the clinical features and mortality rates of patients with novel coronavirus disease (COVID-19), influenza, and respiratory syncytial virus pneumonia.
MATERIAL AND METHODS: A total of 182 patients who were hospitalized at Baskent University Medical Faculty Hospital due to COVID-19, influenza, and RSV were included in the study. Patients were grouped according to their clinical status. Demographic characteristics, comorbidities, laboratory and radiological findings, respiratory support treatments and mortality rates of the patients were recorded and compared between the groups.
RESULTS: The mean age was 69.4±7 years in the COVID-19 group (n:115), 72.9±17.1 years in the influenza group (n:33), and 66.5±22.4 years in the RSV group (n:34). There was no difference in age between the groups (p=0.305). The hospitalization rate was higher for male patients in the COVID-19 group (p=0.036). There was no difference between the groups in terms of comorbidities (p>0.05). There was no difference in mortality rates between the COVID-19, RSV, and influenza patient groups (p=0.260).
CONCLUSIONS: Viral infections with pulmonary involvement require special attention because they can have a poor clinical course. The severity of the clinical course of COVID-19 pneumonia, which causes deaths in the current century, is not different from the clinical course of viral infections such as influenza and RSV.

Keywords

COVID-19, Influenza, Pneumonia, Respiratory syncytial virus

Project Number

KA20/452 – Tarih:15/12/2020

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