HEREDİTER TROMBOFİLİLİ HASTADA TEKRARLAYAN PULMONER EMBOLİ VE ABDOMİNAL AORTADA MURAL TROMBÜS

Year 2020, Volume: 21 Issue: 1, 125 - 128, 20.03.2020

Nuri Köse , Tarık Yıldırım , Gökhan Ergün İbrahim Altun , Fatih Akın

https://doi.org/10.18229/kocatepetip.460178

Abstract

Venöz
tromboembolizm, derin ven trombozu ve/veya pulmoner emboli olarak görülen ciddi
bir klinik durumdur. Derin ven trombozunun ilk atağını geçiren hastalarda
tekrarlama riski artmıştır. Trombofili tromboza yatkınlık olarak tanımlanır ve
kalıtsal ya da kazanılmış olabilir. Herediter trombofili idiyopatik pulmoner
embolizm ve rekürrensi için önemli bir risk faktörüdür. Heterozigot protrombin
G20210A mutasyonu herediter trombofilinin genetik bir formudur ve herediter koagülasyon
bozukluklarının ikinci en sık nedenidir. Bu yazıda tekrarlayan pulmoner emboli
ve abdominal aortada mural trombüs ile başvuran ve herediter trombofili tespit
edilen 76 yaşında bir erkek hastayı sunduk. Bu olgu tekrarlayan pulmoner
embolide altta yatan sebebin araştırılması gerektiğini vurgulamak için
sunulmuştur.

Keywords

Herediter Trombofili, Pulmoner emboli, Tromboz

RECURRENT PULMONARY EMBOLISM AND ABDOMINAL AORTIC MURAL THROMBUS IN THE PATIENT WITH HEREDITARY THROMBOPHILIA

Abstract

Venous thromboembolism is a serious clinical condition that manifests as deep venous thrombosis and/or pulmonary embolism. Patients with a first episode of venous thromboembolism are at an increased risk of new episodes. Thrombophilia is defined as a predisposition to thrombosis and may be inherited or acquired. Hereditary thrombophilia is a major risk factor for idiopathic pulmonary embolism and its recurrence. Prothrombin G20210A heterozygosity is a genetic form of thrombophilia named for a specific mutation and is the second common cause of inherited coagulation disorders. We present case of a 76-year-old male patient presenting with recurrent pulmonary embolism and abdominal aortic mural thrombus who was detected hereditary thrombophilia. The casewas presented in order to emphasize that etiology should be investigated in recurrent pulmonary embolism.

Keywords

Hereditary thrombophilia, pulmonary embolism, thrombosis

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