FACTORS AFFECTING HOSPITAL MORTALITY IN PATIENTS WITH CHRONIC KIDNEY DISEASE HOSPITALIZED FOR HYPERKALEMIA

Year 2024, Volume: 25 Issue: 1 - OCAK 2024 SAYISI, 24 - 29, 17.01.2024

Onur Tunca , Sinan Kazan

https://doi.org/10.18229/kocatepetip.1156825

Abstract

OBJECTIVE: Hyperkalemia is an electrolyte imbalance that can lead to fatal results if not corrected. Patients with chronic kidney disease are prone to be hyperkalemic. Knowing the factors associated with hospital mortality in patients hospitalized for hyperkalemia may reduce mortality caused by hyperkalemia. In the present study, we aimed to research the factors associated with hospital mortality in patients with chronic kidney disease hospitalized for hyperkalemia.
MATERIAL AND METHODS: Patients who were hospitalized in the nephrology clinic between January 2019 and April 2022 and whose serum potassium level was >5.1 mEq/L were included in the study. Patients were divided into two groups as in-hospital deaths and survivors. The groups were compared in terms of laboratory, clinical, and demographic characteristics.
RESULTS: The current study includes 123 cases with a diagnosis of chronic kidney disease. The mean age of the participants was 65.92±13.7 years. Age, diabetes mellitus, coronary artery disease, hemodialysis, potassium level, calcium and pH were found to be independent risk factors for mortality (p= 0.004, p< 0.001, p= 0.004, p=0.009, p=0.001, p=0.007,and p=0.008 respectively).
CONCLUSIONS: Poor outcomes can be reduced by knowing the factors affecting mortality in patients hospitalized for hyperkalemia. In hyperkalemic patients with increased in-hospital mortality risk, the mortality risk can be minimized with additional precautions and rapid intervention.

Keywords

Diabetes mellitus, Hyperkalemia, Mortality, Age

HİPERKALEMİ NEDENİYLE HASTANEYE YATIRILAN KRONİK BÖBREK HASTALIĞI OLAN HASTALARDA HASTANE - İÇİ MORTALİTEYİ ETKİLEYEN FAKTÖRLER

Abstract

AMAÇ: Hiperkalemi düzeltilmediği takdirde ölümcül sonuçlara yol açabilen bir elektrolit inbalansıdır. Kronik böbrek hastalığı olan hastalar hiperkalemik olma eğilimindedir. Hiperkalemi nedeniyle hastaneye yatırılan hastalarda hastane-içi mortalite ile ilişkili faktörleri bilmek hiperkaleminin sebep olduğu mortalitede azalma sağlayabilir. Bu çalışmada hiperkalemi nedeniyle hastaneye yatırılan kronik böbrek hastalığı olan hastalarda hastane-içi mortalite ile ilişkili faktörleri araştırmayı amaçladık.
GEREÇ VE YÖNTEM: Ocak 2019 - Nisan 2022 tarihleri arasında nefroloji kliniğine yatırılan ve serum potasyum düzeyi >5.1 mEq/L olan hastalar çalışmaya dahil edildi. Hastalar hastane-içi ölüm gelişen ve yaşayanlar olarak iki gruba ayrıldı. Gruplar laboratuvar, klinik ve demografik özellikler açısından karşılaştırıldı.
BULGULAR: Mevcut çalışma kronik böbrek hastalığı tanısı olan 123 hastayı içermektedir. Katılımcıların yaş ortalaması 65.92±13.7 yıldı. Yaş, diyabetes mellitus, koroner arter hastalığı, hemodiyaliz, potasyum seviyesi, kalsiyum ve pH mortalite açısından bağımsız birer risk faktörü olarak bulundu (sırasıyla p=0.004, p<0.001, p=0.004, p=0.009, p=0.001, p=0.007 ve p=0.008).
SONUÇ: Hiperkalemi nedeniyle hastaneye yatırılan hastalarda mortaliteyi etkileyen faktörlerin iyi bilinmesi ile kötü sonuçlar azaltılabilir. Hastane-içi mortalite riski artmış hiperkalemik hastalarda alınabilecek ek önlemler ve hızlı müdahale ile mortalite riski en aza indirilebilir.

Keywords

Diyabetes mellitus, Hiperkalemi, Mortalite, Yaş

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