Neuropsychiatric Symptoms in Parkinson’s Disease Patients

Year 2023, Volume: 18 Issue: 3, 105 - 109, 20.11.2023

Tuğba Kaya , Buket Tuğan Yıldız

https://doi.org/10.17517/ksutfd.1214193

Abstract

Many physical, cognitive and psychological symptoms can be seen in neurological diseases. Parkinson's disease (PD) is a neurological disorder arising from the degeneration of neurons, is characterized by motor and non-motor symptoms. Along with motor symptoms, psychiatric symptoms that are included in non-motor symptoms can also be seen in PD. PD symptoms, genetic predisposition, side effects of pharmacological treatments, psychosocial factors; can cause psychiatric conditions such as anxiety, depression, impulse control disorder, and psychosis. It has been determined that the most common psychiatric disorder in PD is depression, followed by anxiety. Although the presence of psychiatric comorbidities in PD is high, it is often overlooked by clinicians during the diagnosis and treatment process. These factors should be taken into account in the diagnosis process and treatment strategies of Parkinson's patients should be structured in a multifactorial manner.

Keywords

Parkinson’s Disease, Neuropsychiatric symptoms, Anxiety, Depression, Impulse control disorder, Psychosis

Parkinson Hastalarında Nöropsikiyatrik Semptomlar

Abstract

Nörolojik hastalıklarda birçok fiziksel, bilişsel ve ruhsal belirtiler kendini gösterebilmektedir. Parkinson hastalığı (PH) nöronların dejenerasyonundan kaynaklanan, motor ve non-motor semptomlar ile karakterize olan nörolojik bir rahatsızlıktır. PH’da da motor semptomlarla beraber, non-motor semptomlar içerisine dahil olan psikiyatrik belirtiler görülebilmektedir. PH semptomları, genetik yatkınlık, uygulanan farmakolojik tedavilerin yan etkileri, psikososyal faktörler; anksiyete, depresyon, dürtü kontrol bozukluğu, psikoz gibi psikiyatrik durumların ortaya çıkmasına neden olabilmektedir. PH’de en sık görülen psikiyatrik bozukluğun depresyon olduğu, onu takip eden psikiyatrik bozukluğun ise anksiyete olduğu saptanmıştır. PH’de psikiyatrik komorbitelerin varlığı yüksek oranda olmasına rağmen, tanı ve tedavi sürecinde çoğunlukla klinisyenlerin gözünden kaçmaktadır. Tanı sürecinde bu faktörler dikkate alınmalı ve Parkinson Hastalarının tedavi stratejileri multifaktöriyel bir şekilde yapılandırılmalıdır.

Keywords

Parkinson hastalığı, Nöropsikiyatrik semptomlar, Anksiyete, Depresyon, İmpuls kontrol bozukluğu, Psikoz

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