Obez Çocuklarda ve Sağlıklı Kontrol Grubunda Ön Segment Parametrelerinin Karşılaştırılması

Year 2023, , 190 - 196, 22.06.2023

Mehmet Tahir Eski , Kuddusi Teberik , Taha Sezer , İlknur Arslanoğlu

https://doi.org/10.18521/ktd.1194775

Abstract

Amaç
Obez çocuklarda ön segment parametrelerinin değerlendirilmesi
Gereç ve yöntemler: 55 obez ve 30 kontrol grubu çocuk denek katıldı. Tüm katılımcılar ve kontrol grubu incelendi ve antropometrik ölçümler yapıldı. Açlık kan şekeri (AKŞ), trigliserit(TG), toplam kolesterol (TC), yüksek yoğunluklu lipoprotein-kolesterol (HDL-K), düşük yoğunluklu lipoprotein-kolesterol (LDL-K) ve insülin değerleri ölçümleri yapıldı. . İnsülin direncinin (HOMA‑IR) homeostaz modeli değerlendirmesi hesaplandı. Her katılımcıya detaylı bir göz muayenesi yapıldı ve Göz içi basıncı(GİB), Santral kornea kalınlığı (SKK), Ön kamara derinliği (ÖKD) ve Lens kalınlığı (LK) ölçüldü.
Bulgular: Grupların cinsiyet dağılımı benzerdi (p=0,893). SKK ve LT ortalaması obez grupta anlamlı olarak daha yüksekti (572.9 ± 14.5'e karşılık 559.5 ± 10.1 µm, p=0.001; 3.6 ± 0.14'e karşı 3.48 ± 0.25 mm, p=0.007). Obez ve kontrol grupları arasında diğer parametreler açısından anlamlı fark bulunmadı. BMI ve WC, LT kontrol grupları ile anlamlı bir negatif korelasyona sahipti. Obez grup, GİB ile TG arasında anlamlı bir pozitif korelasyon (r=0.276, p=0.042) ve HDL-C ile anlamlı bir negatif korelasyon gösterdi (r=-0.273, p=0.043). Kontrol grubunda GİB ile VKİ (r=0.389, p=0.034), WC (r=0.497, p=0.005), HOMA-IR (r=0.384, p=0.036), İnsülin arasında anlamlı pozitif ilişki vardı. (r=0.407, p=0.026) ve TC ile anlamlı bir negatif korelasyon (r=-0.511, p=0.004). Kontrol grubunda AKD ile LDL-K arasında anlamlı pozitif korelasyon (r=0.371, p=0.043) ve HOMA-IR arasında anlamlı derecede negatif korelasyon saptandı (r=-0.682, p=0.000).
Sonuç: Obez grup, kontrol gruplarına göre daha yüksek SKK ve LT'ye sahipti.

Keywords

Obez çocuklar, Kornea kalınlığı, Ön kamara derinliği, Lens kalınlığı, Göz içi basıncı

Comparison of Anterior Segment Parameters in Obese Children And Healthy Control Group

Abstract

Objective:: To evaluate anterior segment parameters in obese children
Material and methods: 55 obese and 30 control group children subjects participated. All participants and the control group were examined and anthropometric measurements were made. The measurements of fasting blood glucose(FBG), triglyceride(TG), total cholesterol (TC), high-density lipoprotein-cholesterol (HDL-C), low-density lipoprotein-cholesterol (LDL-C), and insulin values were performed. The homeostasis model assessment of insulin resistance (HOMA‑IR) was calculated. Each participant underwent a detailed ophthalmic examination and IOP, CCT, ACD and LT were measured.
Results: The gender distribution of the groups was similar (p=0.893). The mean of CCT and LT were significantly higher in the obese group (572.9 ± 14.5 vs. 559.5 ± 10.1 µm, p=0.001; 3.6 ± 0.14 vs. 3.48 ± 0.25 mm, p=0.007) . No significant difference was found between the obese and control groups in terms of other parameters. BMI and WC had a significant negative correlation with LT control groups. The obese group showed a significant positive correlation between IOP and TG (r=0.276, p=0.042), and a significant negative correlation with HDL-C (r=-0.273, p=0.043). In the control group, there was a significant positive correlation between IOP and BMI (r=0.389, p=0.034), WC (r=0.497, p=0.005), HOMA-IR (r=0.384, p=0.036), Insulin (r=0.407, p=0.026), and a significant negative correlation with TC (r=-0.511, p=0.004). A significantly positive correlation between ACD and LDL-C (r=0.371, p=0.043) and a significantly negative correlation between HOMA-IR in the control group were detected (r=-0.682, p=0.000).
Conclusion: The obese group had higher CCT and LT than the control groups.

Keywords

Obese children, Corneal thickness, Anterior chamber depth, Lens thickness, Intra ocular pressure

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