Abstract
Perineurioma is a rare benign peripheral nerve sheath tumor of perineural cells. To separate from similar tumors, CD10, EMA positivity and CD34, S100 negativity is important. To distinguish between tumors having similar morphology, immunohistochemical tests and the morphological findings should be evaluated together with. In this study, 30-year old female patient having a soft tissue Perineurioma localized in the deltoid muscle and 66 year-old female patient with intraneural perineurioma localized in the buccal mucosal was presented and differential diagnosis was discussed
Keywords
References
- Weiss SW, Goldblum JR (eds). Enzinger and Weiss’s Soft Tissue Tumors. 4th ed. Philadelphia, Pa: Mosby; 2001; 1173-8.
- Kim JM, Choi JH. Soft tissue perineurioma: a case report. Korean J Pathol 2009; 43(3): 266-70.
- Suster D, Plaza JA, Shen R. Low-grade malignant perineurioma (perineurial sarcoma) of soft tissue: a potential diagnostic pitfall on fine needle aspiration. Ann Diagn Pathol. 2005; 9(4):197-201.
- Hornick J, Fletcher C. Soft tissue perineurioma clinicopathologic analysis of 81 cases including those with atypical histologic features. Am J Surg Pathol 2005; 29(7):845-58.
- Fetsch JF, Miettinen M. Sclerosing perineurioma: a clinicopathologic study of 19 cases of a distinctive soft tissuelesion with a predilection for the fingers and palms of young adults. Am J Surg Pathol 1997; 21(12):1433-42.
- Duncan L, Tharp DR, Branca P, Lyons J. Endobronchial Perineurioma: An Unusual Soft Tissue Lesion in an Unreported Location. Pathology Research International. 2010; 2010: 613-824.
- Macarenco RS, Ellinger F, Oliveira AM. Perineurioma: a distinctive and underrecognized peripheral nerve sheath neoplasm. Arch Pathol Lab Med 2007; 131(4):625-36.
- Giannini C, Scheithauer BW, Jenkins RB, et al. Soft-tissue perineurioma: evidence for an abnormality of chromosome 22, criteria for diagnosis, and review of the literature. Am J Surg Pathol 1997; 21(2):164-73.
- Tomaru U, Hasegawa T, Hasegawa F, Kito M, Hirose T, Shimoda T. Primary extracranial meningioma of the foot: a case report. Jpn J Clin Oncol 2000; 30(7):313-7.
- Gleason BC, Fletcher CD. Deep “benign” fibrous histiocytoma: clinicopathologic analysis of 69 cases of a rare tumor indicating occasional metastatic potential. Am J Surg Pathol 2008; 32(3):354-62.
Abstract
Perinöromalar, nadir görülen perinöral hücrelerden gelişen benign periferik sinir kılıf tümörüdür. Perinöromaya benzer tümörlerden ayrımı için CD10, EMA pozitifliği ile S100 ve CD34 negatifliği önemlidir. Perinöromaya benzer morfolojiye sahip tümörler arasında ayırım yapılması için immünhistokimyasal testler ile morfolojik bulguların birlikte değerlendirilmesi gerekir. Bu çalışmada 30 yaşında kadın hastada deltoid kas içinde yerleşim gösteren soft tissue perinöroma ile 66 yaşında kadın hastada bukkal mukoza yerleşimli intranöral perinöroma olgularının ayırıcı tanıları tartışılmıştır
Keywords
References
- Weiss SW, Goldblum JR (eds). Enzinger and Weiss’s Soft Tissue Tumors. 4th ed. Philadelphia, Pa: Mosby; 2001; 1173-8.
- Kim JM, Choi JH. Soft tissue perineurioma: a case report. Korean J Pathol 2009; 43(3): 266-70.
- Suster D, Plaza JA, Shen R. Low-grade malignant perineurioma (perineurial sarcoma) of soft tissue: a potential diagnostic pitfall on fine needle aspiration. Ann Diagn Pathol. 2005; 9(4):197-201.
- Hornick J, Fletcher C. Soft tissue perineurioma clinicopathologic analysis of 81 cases including those with atypical histologic features. Am J Surg Pathol 2005; 29(7):845-58.
- Fetsch JF, Miettinen M. Sclerosing perineurioma: a clinicopathologic study of 19 cases of a distinctive soft tissuelesion with a predilection for the fingers and palms of young adults. Am J Surg Pathol 1997; 21(12):1433-42.
- Duncan L, Tharp DR, Branca P, Lyons J. Endobronchial Perineurioma: An Unusual Soft Tissue Lesion in an Unreported Location. Pathology Research International. 2010; 2010: 613-824.
- Macarenco RS, Ellinger F, Oliveira AM. Perineurioma: a distinctive and underrecognized peripheral nerve sheath neoplasm. Arch Pathol Lab Med 2007; 131(4):625-36.
- Giannini C, Scheithauer BW, Jenkins RB, et al. Soft-tissue perineurioma: evidence for an abnormality of chromosome 22, criteria for diagnosis, and review of the literature. Am J Surg Pathol 1997; 21(2):164-73.
- Tomaru U, Hasegawa T, Hasegawa F, Kito M, Hirose T, Shimoda T. Primary extracranial meningioma of the foot: a case report. Jpn J Clin Oncol 2000; 30(7):313-7.
- Gleason BC, Fletcher CD. Deep “benign” fibrous histiocytoma: clinicopathologic analysis of 69 cases of a rare tumor indicating occasional metastatic potential. Am J Surg Pathol 2008; 32(3):354-62.
Details
| Primary Language | Turkish |
|---|---|
| Journal Section | Articles |
| Authors | |
| Publication Date | April 1, 2015 |
| Published in Issue | Year 2015 |