Review
BibTex RIS Cite

Rhythm and Conduction disturbances in patients with COVID-19 and their significance in family medicine practice

Year 2024, , 205 - 209, 30.06.2024
https://doi.org/10.18521/ktd.1487828

Abstract

SARS-Cov-2 (Severe acute respiratory syndrome coronavirus 2) belongs to the group of viruses containing ribonucleic acid (RNA). The most common clinical manifestations include fever, upper and/or lower respiratory tract involvement of varying severity. As the incidence of the disease increases and information about its course accumulates, it is known that there is an increased mortality from cardiovascular complications, including as a result of arrhythmias. It is assumed that the main mechanisms by which they occur are the entry of the virus into the heart cell through the expression of angiotensin-converting enzyme receptor 2, which leads to increased levels of angiotensin 2 and its many-sided negative effects, the development of a systemic inflammatory over-response (cytokine storm), directly cardiac damage, hypoxia, electrolyte disturbances, water imbalance. The disorders that are registered are tachyarrhythmias and bradyarrhythmias. In the conditions of the emerging COVID-19 (coronavirus disease of 2019) pandemic, general practitioners in Bulgaria played a significant role in the diagnosis and treatment of this disease. Of particular importance is their competence regarding the establishment of possible complications from the cardiovascular system. Knowledge of the most common rhythm and conduction disorders, as well as the mechanisms of their occurrence, are decisive for the correct management and their potential outcome.

References

  • 1. Coronavirus: From bats to pangolins, how do viruses reach us?. // Deutsche Welle, 7 February 2020.
  • 2. Hessami A, Shamshiriand A, Heydari KD, et al. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource center is hosted on Elsevier Connect, the company’s public news and information. 2020;(January).
  • 3. Shoar S, Hosseini DM F, D M. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource center is hosted on Elsevier Connect, the company’s public news and information. 2020;(January).
  • 4. Zeng L, Wang S, Cai J, Sun S, Wang S, Li J et al. Clinical characteristics of COVID-19 with cardiac injury: a systematic review and meta-analysis. Epidemiol Infect. 2020;148. Published online.
  • 5. Teng S, Tang Q. ACE2 enhance viral infection or viral infection aggravate the underlying diseases. Comput Struct Biotechnol J. 2020;18:2100–6.
  • 6. Alwaqfi NR, Ibrahim KS. COVID-19: an update and cardiac involvement. J Cardiothorac Surg. 2020;15:239.
  • 7. Lindner D, Fitzek A, Bräuninger H, Aleshcheva G, Edler C, Meissner K, et al. Association of Cardiac Infection With SARS-CoV-2 in Confirmed COVID-19 Autopsy Cases. JAMA Cardiol. 2020;5(11):1281-5
  • 8. Guo T, Fan Y, Chen M, Wu X, Zhang L, He T, et al. Cardiovascular implications of fatal outcomes of patients with coronavirus disease 2019 (COVID-19) JAMA Cardiol. 2020;5(7):811–8.
  • 9. Shi S, Qin M, Shen B, Cai Y, Liu T, Yang , et al. Association of cardiac injury with mortality in hospitalized patients With COVID-19 in Wuhan, China. JAMA Cardiol. 2020;5(7):802–10.
  • 10. Nabeh OA, Helaly MM, Menshawey R, Menshawey E, Nasser MMM, Diaa El-Deen AM. Contemporary approach to understand and manage COVID-19-related arrhythmia. Egypt Heart J. 2021;73:76.
  • 11. Furqan MM, Verma BR, Cremer PC, Imazio M, Klein AL. Pericardial Diseases in COVID19: a Contemporary Review. Curr Cardiol Rep. 2021;23(7):90.
  • 12. Angeli F, Spanevello A, De Ponti R, Visca D, Marazzato J, Palmiotto G, et al. Electrocardiographic features of patients with COVID-19 pneumonia. Eur J Intern Med. 2020;78:101–6.
  • 13. Yang LC, Zhang RT, Guo LJ, Xiao H, Zu LY, Zhang YY, et al. Hypoxia and inflammation are risk factors for acute myocardial injury in patients with coronavirus disease 2019. Beijing Da Xue Xue Bao Yi Xue Ban. 2020;53(1):159-66. Chinese. 14. Dherange P, Lang J. Qian P, Oberfeld B. Sauer WH, Koplan B, et al. Arrhythmias and COVID-19: a review. J Am Coll Cardiol EP. 2020;6:1193–204.
  • 15. Wanamaker B, Cascino T, McLaughlin V, Oral H, Latchamsetty R, Siontis KC. Atrial arrhythmias in pulmonary hypertension: pathogenesis, prognosis and management. Arrhythm Electrophysiol Rev. 2018;7:43–8.
  • 16. Oliver MF. Control of free fatty acids during acute myocardial ischaemia. Heart. 2010;96:1883–84.
  • 17. Gettes L.S. Electrolyte abnormalities underlying lethal and ventricular arrhythmias. Circulation. 1992;85(1 Suppl):I70–6.
  • 18. Darpo B. Spectrum of drugs prolonging QT interval and the incidence of torsades de pointes. Eur Heart J Supplements. 2001;3(suppl K):S70–S80.
  • 19. Wu CI, Postema PG, Arbelo E, Behr ER, Bezzina CR, Napolitano C, et al. SARS-CoV-2, COVID-19, and inherited arrhythmia syndromes. Heart Rhythm. 2020;17:1456–62.
  • 20. Walsh EP, Cecchin F. Arrhythmias in adult patients with congenital heart disease. Circulation. 2007;115:534–45.
  • 21. Parmley W.W. Factors causing arrhythmias in chronic congestive heart failure. Am Heart J. 1987;114:1267–1272. doi: 10.1016/0002-8703(87)90215-8.
  • 22. Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus–infected pneumonia in Wuhan, China. JAMA. 2020;323:1061–9.
  • 23. Bhatla A, Mayer MM, Adusumalli S, Hyman MC, Oh E, Tierney A, et al. COVID-19 and cardiac arrhythmias. Heart Rhythm. 2020;17:1439–44.
  • 24. Lakkireddy DR, Chung MK, Gopinathannair R, Patton KK, Gluckman TJ, Turagam M, et al. Guidance for cardiac electrophysiology during the COVID-19 pandemic from the Heart Rhythm Society COVID-19 Task Force; Electrophysiology Section of the American College of Cardiology; and the Electrocardiography and Arrhythmias Committee of the Council on Clinical Cardiology, American Heart Association. Circulation. 2020;141:e823–e831.
  • 25. Goyal P, Choi JJ, Pinheiro LC, Schenck EJ, Chen R, Jabri A, et al. Clinical characteristics of Covid-19 in New York city. N Engl J Med. 2020;382:2372–4.
  • 26. Chen Q, Xu L, Dai Y, Ling Y, Mao J, Qian J, et al. Cardiovascular manifestations in severe and critical patients with COVID-19. Clin Cardiol. 2020;43:796–802.
  • 27. Gopinathannair R, Merchant FM, Lakkireddy DR, Etheridge SP, Feigofsky S, Han JK, et al. COVID-19 and cardiac arrhythmias: a global perspective on arrhythmia characteristics and management strategies. J Interv Card Electrophysiol. 2020;59:329–36. 28. Gatto MC, Persi A, Tung M, Masi R, Canitano S, Kol A. Bradyarrhythmias in patients with SARS-CoV-2 infection: A narrative review and a clinical report. Pacing Clin Electrophysiol. 2021;44(9):1607-15.

COVİD-19 hastalarında ritim ve ileti anormallikleri ve bunların aile hekimliği pratiğindeki önemi

Year 2024, , 205 - 209, 30.06.2024
https://doi.org/10.18521/ktd.1487828

Abstract

SARS-Cov-2 (Şiddetli akut solunum sendromu koronavirüsü 2) ribonükleik asit içeren virüsler grubuna aittir. (RNA). En yaygın klinik belirtiler arasında, farklı derecede ateş, üst ve/veya alt solunum yolu etkisi vardır. Hastalığın görülme oranı arttıkça ve bu hastalığın ilerlemesi hakkında bilgi biriktirdiğinde, kardiyovasküler komplikasyonlar, aritmi sonuçları da dahil olmak üzere ölüm oranının arttığı biliniyor. Bunların meydana geldiği ana mekanizmalar, angiotensin dönüştüren enzim reseptör 2'nin ifadesi yoluyla kalp hücresine virüsün girmesidir, bu da angiotensin 2 seviyelerinin artmasına ve çok yönlü olumsuz etkileri, sistemik iltihaplı aşırı tepki (sitokin fırtınası), doğrudan kalp hasarı, hipoksi, elektrolit bozuklukları, su dengesizliği gelişmesine yol açar. Kayıtlı hastalıklar taşiaritmi ve bradiaritmi'dir. Gelişen COVID-19 (Koronavirüs hastalığı 2019) salgını koşullarında, Bulgaristan'daki genel tıp uzmanları bu hastalığın teşhisinde ve tedavisinde önemli bir rol oynadı. Özellikle kardiyovasküler sistemle ilgili olası komplikasyonların tespiti konusunda yetkinlikleri önemlidir. En yaygın ritm ve iletkenlik bozukluklarının yanı sıra bunların ortaya çıkış mekanizmalarının bilinmesi doğru yönetimi ve potansiyel sonuçları için çok önemlidir.

References

  • 1. Coronavirus: From bats to pangolins, how do viruses reach us?. // Deutsche Welle, 7 February 2020.
  • 2. Hessami A, Shamshiriand A, Heydari KD, et al. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource center is hosted on Elsevier Connect, the company’s public news and information. 2020;(January).
  • 3. Shoar S, Hosseini DM F, D M. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource center is hosted on Elsevier Connect, the company’s public news and information. 2020;(January).
  • 4. Zeng L, Wang S, Cai J, Sun S, Wang S, Li J et al. Clinical characteristics of COVID-19 with cardiac injury: a systematic review and meta-analysis. Epidemiol Infect. 2020;148. Published online.
  • 5. Teng S, Tang Q. ACE2 enhance viral infection or viral infection aggravate the underlying diseases. Comput Struct Biotechnol J. 2020;18:2100–6.
  • 6. Alwaqfi NR, Ibrahim KS. COVID-19: an update and cardiac involvement. J Cardiothorac Surg. 2020;15:239.
  • 7. Lindner D, Fitzek A, Bräuninger H, Aleshcheva G, Edler C, Meissner K, et al. Association of Cardiac Infection With SARS-CoV-2 in Confirmed COVID-19 Autopsy Cases. JAMA Cardiol. 2020;5(11):1281-5
  • 8. Guo T, Fan Y, Chen M, Wu X, Zhang L, He T, et al. Cardiovascular implications of fatal outcomes of patients with coronavirus disease 2019 (COVID-19) JAMA Cardiol. 2020;5(7):811–8.
  • 9. Shi S, Qin M, Shen B, Cai Y, Liu T, Yang , et al. Association of cardiac injury with mortality in hospitalized patients With COVID-19 in Wuhan, China. JAMA Cardiol. 2020;5(7):802–10.
  • 10. Nabeh OA, Helaly MM, Menshawey R, Menshawey E, Nasser MMM, Diaa El-Deen AM. Contemporary approach to understand and manage COVID-19-related arrhythmia. Egypt Heart J. 2021;73:76.
  • 11. Furqan MM, Verma BR, Cremer PC, Imazio M, Klein AL. Pericardial Diseases in COVID19: a Contemporary Review. Curr Cardiol Rep. 2021;23(7):90.
  • 12. Angeli F, Spanevello A, De Ponti R, Visca D, Marazzato J, Palmiotto G, et al. Electrocardiographic features of patients with COVID-19 pneumonia. Eur J Intern Med. 2020;78:101–6.
  • 13. Yang LC, Zhang RT, Guo LJ, Xiao H, Zu LY, Zhang YY, et al. Hypoxia and inflammation are risk factors for acute myocardial injury in patients with coronavirus disease 2019. Beijing Da Xue Xue Bao Yi Xue Ban. 2020;53(1):159-66. Chinese. 14. Dherange P, Lang J. Qian P, Oberfeld B. Sauer WH, Koplan B, et al. Arrhythmias and COVID-19: a review. J Am Coll Cardiol EP. 2020;6:1193–204.
  • 15. Wanamaker B, Cascino T, McLaughlin V, Oral H, Latchamsetty R, Siontis KC. Atrial arrhythmias in pulmonary hypertension: pathogenesis, prognosis and management. Arrhythm Electrophysiol Rev. 2018;7:43–8.
  • 16. Oliver MF. Control of free fatty acids during acute myocardial ischaemia. Heart. 2010;96:1883–84.
  • 17. Gettes L.S. Electrolyte abnormalities underlying lethal and ventricular arrhythmias. Circulation. 1992;85(1 Suppl):I70–6.
  • 18. Darpo B. Spectrum of drugs prolonging QT interval and the incidence of torsades de pointes. Eur Heart J Supplements. 2001;3(suppl K):S70–S80.
  • 19. Wu CI, Postema PG, Arbelo E, Behr ER, Bezzina CR, Napolitano C, et al. SARS-CoV-2, COVID-19, and inherited arrhythmia syndromes. Heart Rhythm. 2020;17:1456–62.
  • 20. Walsh EP, Cecchin F. Arrhythmias in adult patients with congenital heart disease. Circulation. 2007;115:534–45.
  • 21. Parmley W.W. Factors causing arrhythmias in chronic congestive heart failure. Am Heart J. 1987;114:1267–1272. doi: 10.1016/0002-8703(87)90215-8.
  • 22. Wang D, Hu B, Hu C, Zhu F, Liu X, Zhang J, et al. Clinical characteristics of 138 hospitalized patients with 2019 novel coronavirus–infected pneumonia in Wuhan, China. JAMA. 2020;323:1061–9.
  • 23. Bhatla A, Mayer MM, Adusumalli S, Hyman MC, Oh E, Tierney A, et al. COVID-19 and cardiac arrhythmias. Heart Rhythm. 2020;17:1439–44.
  • 24. Lakkireddy DR, Chung MK, Gopinathannair R, Patton KK, Gluckman TJ, Turagam M, et al. Guidance for cardiac electrophysiology during the COVID-19 pandemic from the Heart Rhythm Society COVID-19 Task Force; Electrophysiology Section of the American College of Cardiology; and the Electrocardiography and Arrhythmias Committee of the Council on Clinical Cardiology, American Heart Association. Circulation. 2020;141:e823–e831.
  • 25. Goyal P, Choi JJ, Pinheiro LC, Schenck EJ, Chen R, Jabri A, et al. Clinical characteristics of Covid-19 in New York city. N Engl J Med. 2020;382:2372–4.
  • 26. Chen Q, Xu L, Dai Y, Ling Y, Mao J, Qian J, et al. Cardiovascular manifestations in severe and critical patients with COVID-19. Clin Cardiol. 2020;43:796–802.
  • 27. Gopinathannair R, Merchant FM, Lakkireddy DR, Etheridge SP, Feigofsky S, Han JK, et al. COVID-19 and cardiac arrhythmias: a global perspective on arrhythmia characteristics and management strategies. J Interv Card Electrophysiol. 2020;59:329–36. 28. Gatto MC, Persi A, Tung M, Masi R, Canitano S, Kol A. Bradyarrhythmias in patients with SARS-CoV-2 infection: A narrative review and a clinical report. Pacing Clin Electrophysiol. 2021;44(9):1607-15.
There are 26 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Reviews
Authors

Nevena Ivanova 0000-0002-4213-8142

Publication Date June 30, 2024
Submission Date May 21, 2024
Acceptance Date June 22, 2024
Published in Issue Year 2024

Cite

APA Ivanova, N. (2024). Rhythm and Conduction disturbances in patients with COVID-19 and their significance in family medicine practice. Konuralp Medical Journal, 16(2), 205-209. https://doi.org/10.18521/ktd.1487828
AMA Ivanova N. Rhythm and Conduction disturbances in patients with COVID-19 and their significance in family medicine practice. Konuralp Medical Journal. June 2024;16(2):205-209. doi:10.18521/ktd.1487828
Chicago Ivanova, Nevena. “Rhythm and Conduction Disturbances in Patients With COVID-19 and Their Significance in Family Medicine Practice”. Konuralp Medical Journal 16, no. 2 (June 2024): 205-9. https://doi.org/10.18521/ktd.1487828.
EndNote Ivanova N (June 1, 2024) Rhythm and Conduction disturbances in patients with COVID-19 and their significance in family medicine practice. Konuralp Medical Journal 16 2 205–209.
IEEE N. Ivanova, “Rhythm and Conduction disturbances in patients with COVID-19 and their significance in family medicine practice”, Konuralp Medical Journal, vol. 16, no. 2, pp. 205–209, 2024, doi: 10.18521/ktd.1487828.
ISNAD Ivanova, Nevena. “Rhythm and Conduction Disturbances in Patients With COVID-19 and Their Significance in Family Medicine Practice”. Konuralp Medical Journal 16/2 (June 2024), 205-209. https://doi.org/10.18521/ktd.1487828.
JAMA Ivanova N. Rhythm and Conduction disturbances in patients with COVID-19 and their significance in family medicine practice. Konuralp Medical Journal. 2024;16:205–209.
MLA Ivanova, Nevena. “Rhythm and Conduction Disturbances in Patients With COVID-19 and Their Significance in Family Medicine Practice”. Konuralp Medical Journal, vol. 16, no. 2, 2024, pp. 205-9, doi:10.18521/ktd.1487828.
Vancouver Ivanova N. Rhythm and Conduction disturbances in patients with COVID-19 and their significance in family medicine practice. Konuralp Medical Journal. 2024;16(2):205-9.