Review
Year 2016,
Volume: 8 Issue: 3, 5 - 10, 05.05.2016
Abstract
Abstract
Probiotics have effects on both innate (the initial immune system to pathogens)and to adaptive (immune system recognizes) immune systems. In non-specific immunity, they increase mucin production, inhibit growth of potential pathogens, decrease intestine permeability and increase activity of natural killers and macrophages, and increase phagocytosis. In adaptive immunity, they increase the number of cellssecreting IgA, G and M; increase specific secretory IgA in serum and intestine andregulate intestinal immune response.
Keywords
References
- Kaynaklar 1.MacDonald TT, Spencer J. Ontogeny of the gut-associatedlymphoid system in man. Acta Paediatr Suppl 1994; 83: 3-5. 2.Pickard KM, Bremner AR, Gordon JN, MacDonald TT. Mic-robial-gut interactions in health and disease. Immune respon-ses. Best Pract Res Clin Gastroenterol 2004; 18: 271-85. 3.Cebra JJ. Influences of microbiota on intestinal immune systemdevelopment. Am J Clin Nutr 1999; 69: 1046S-1051S. 4.Delcenserie V, Martel D, Lamoureux M, Amiot J, Boutin Y,Roy D. Immunomodulatory effects of probiotics in the intes-tinal tract. Curr Issues Mol Biol 2009; 10: 37-54. 5.Cummings JH, Antoine JM, Azpiroz F, et al. PASSCLAIM--gut health and immunity. Eur J Nutr 2004; 43: Suppl II118-II173. 6.Harmsen HJ, Wildeboer-Veloo AC, Raangs GC, et al. Analy-sis of intestinal flora development in breast-fed and formula-fed infants by using molecular identification and detection met-hods. J Pediatr Gastroenterol Nutr 2000; 30: 61-67. 7.Yoshioka H, Iseki K, Fujita K. Development and differencesof intestinal flora in the neonatal period in breast-fed and bott-le-fed infants. Pediatrics 1983; 72: 317-21. 8.MacDonald TT, Gordon JN. Bacterial regulation of intesti-nal immune responses. Gastroenterol Clin North Am 2005;34: 401, vii. 9.Servin AL. Antagonistic activities of lactobacilli and bifido-bacteria against microbial pathogens. FEMS Microbial Rev2004; 28: 405-40. 10.Mack DR, Michail S, Wei S, McDougall L, Hollingsworth MA.Probiotics inhibit enteropathogenic E. coli adherence in vit-ro by inducing intestinal mucin gene expression. Am J Physi-ol 1999; 276: G941-950. 11.Pessi T, Sütas Y, Hurme M, Isolauri E. Interleukin-10 gene-ration in atopic children following oral Lactobacillus rham-nosus GG. Clin Exp Allergy 2000; 30: 1804-808. 12.Fukushima Y, Kawata Y, Hara H, Terada A, Mitsuoka T. Effectof a probiotic formula on intestinal immunoglobulin A produc-tion in healthy children. Int J Food Microbiol 1998; 42: 39-44. 13.Bakker-Zierikzee AM, Tol EA, Kroes H, Kok FJ, Bindels JG.Faecal SIgA secretion in infants fed on pre- or probiotic in-fant formula. Pediatr Allergy Immunol 2006; 17: 134-40. 14.Köhler H, Donarski S, Stocks B, Parret A, Edwards C, Schro-ten H. Antibacterial characteristics in the feces of breast-fedand formula-fed infants during the first year of life. J Pedi-atr Gastroenterol Nutr 2002; 34: 188-93. 15.Kalliomäki M, Salminen S, Arvilommi H, Kero P, KoskinenP, Isolauri E. Probiotics in primary prevention of atopic di-sease: a randomised placebo-controlled trial. Lancet 2001;357: 1076-79. 16.Björkstén B. Allergy prevention. Interventions during preg-nancy and early infancy. Clin Rev Allergy Immunol 2004; 26:129-38. 17.Millar M, Wilks M, Costeloe K. Probiotics for preterm infants?Arch Dis Child Fetal Neonatal Ed 2003; 88: F354-358.18.Linskens RK, Huijsdens XW, Savelkoul PH, Vandenbroucke-Grauls CM, Meuwissen SG. The bacterial flora in inflamma-tory bowel disease: current insights in pathogenesis and theinfluence of antibiotics and probiotics. Scand J Gastroente-rol 2001; (Suppl): 29-40. 19.Rautava S, Ruuskanen O, Ouwehand A, Salminen S, Isolau-ri E. The hygiene hypothesis of atopic disease-an extended ver-sion. J Pediatr Gastroenterol Nutr 2004; 38: 378-88. 20.Kirjavainen PV, Arvola T, Salminen SJ, Isolauri E. Aberrantcomposition of gut microbiota of allergic infants: a target ofbifidobacterial therapy at weaning? Gut 2002; 51: 51-55. 21.Mohan R, Koebnick C, Schildt J, et al. Effects of Bifidobac-terium lactis Bb12 supplementation on intestinal microbiotaof preterm infants: a double-blind, placebo-controlled, ran-domized study. J Clin Microbiol 2006; 44: 4015-31. 22.Gill HS, Rutherfurd KJ, Cross ML. Dietary probiotic supp-lementation enhances natural killer cell activity in the elderly:an investigation of age-related immunological changes. J ClinImmunol 2001; 21: 264-71. 23.Ogawa T, Asai Y, Tamai R, et al. Natural killer cell activiti-es of synbiotic Lactobacillus casei ssp. casei in conjunctionwith dextran. Clin Exp Immunol 2006; 143: 103-109. 24.Rinne M, Kalliomaki M, Arvilommi H, Salminen S, IsolauriE. Effect of probiotics and breastfeeding on the bifidobacte-rium and lactobacillus/enterococcus microbiota and humo-ral immune responses. J Pediatr 2005; 147: 186-91. 25.Lin HC, Su BH, Chen AC, et al. Oral probiotics reduce theincidence and severity of necrotizing enterocolitis in very lowbirth weight infants. Pediatrics 2005; 115: 1-4. 26.Galdeano CM, Pergidon C. Role of viability of probiotic stra-ins in their persistence in the gut and in mucosal immune sti-mulation. J Appl Microbiol 2004; 97: 673-81.
Year 2016,
Volume: 8 Issue: 3, 5 - 10, 05.05.2016
Abstract
Öz
Probiyotiklerin ilk (patojenlerle ilk karşılaşma sonucu ortaya çıkan yanıt) ve adaptif (hatırlananlara karşı gelişen immün yanıt) immünite üzerine etkileri vardır. İlk nonspesifik immünitede müsin üretimini arttırırlar, olası patojenlerin büyümesini inhibe ederler, bağırsak geçirgenliğini azaltırlar ve doğal öldürücü hücre aktivitesini, makrofaj aktivasyonunu ve fagositozu arttırırlar. Adaptif immünitede ise IgA, IgG ve IgMsalgılayan hücreleri arttırırlar, serum ve bağırsak lümenindeki total ve spesifik sekretuvar IgA’yı arttırırlar, inflamatuvar bağırsak immün yanıtını düzenlerler.
Keywords
References
- Kaynaklar 1.MacDonald TT, Spencer J. Ontogeny of the gut-associatedlymphoid system in man. Acta Paediatr Suppl 1994; 83: 3-5. 2.Pickard KM, Bremner AR, Gordon JN, MacDonald TT. Mic-robial-gut interactions in health and disease. Immune respon-ses. Best Pract Res Clin Gastroenterol 2004; 18: 271-85. 3.Cebra JJ. Influences of microbiota on intestinal immune systemdevelopment. Am J Clin Nutr 1999; 69: 1046S-1051S. 4.Delcenserie V, Martel D, Lamoureux M, Amiot J, Boutin Y,Roy D. Immunomodulatory effects of probiotics in the intes-tinal tract. Curr Issues Mol Biol 2009; 10: 37-54. 5.Cummings JH, Antoine JM, Azpiroz F, et al. PASSCLAIM--gut health and immunity. Eur J Nutr 2004; 43: Suppl II118-II173. 6.Harmsen HJ, Wildeboer-Veloo AC, Raangs GC, et al. Analy-sis of intestinal flora development in breast-fed and formula-fed infants by using molecular identification and detection met-hods. J Pediatr Gastroenterol Nutr 2000; 30: 61-67. 7.Yoshioka H, Iseki K, Fujita K. Development and differencesof intestinal flora in the neonatal period in breast-fed and bott-le-fed infants. Pediatrics 1983; 72: 317-21. 8.MacDonald TT, Gordon JN. Bacterial regulation of intesti-nal immune responses. Gastroenterol Clin North Am 2005;34: 401, vii. 9.Servin AL. Antagonistic activities of lactobacilli and bifido-bacteria against microbial pathogens. FEMS Microbial Rev2004; 28: 405-40. 10.Mack DR, Michail S, Wei S, McDougall L, Hollingsworth MA.Probiotics inhibit enteropathogenic E. coli adherence in vit-ro by inducing intestinal mucin gene expression. Am J Physi-ol 1999; 276: G941-950. 11.Pessi T, Sütas Y, Hurme M, Isolauri E. Interleukin-10 gene-ration in atopic children following oral Lactobacillus rham-nosus GG. Clin Exp Allergy 2000; 30: 1804-808. 12.Fukushima Y, Kawata Y, Hara H, Terada A, Mitsuoka T. Effectof a probiotic formula on intestinal immunoglobulin A produc-tion in healthy children. Int J Food Microbiol 1998; 42: 39-44. 13.Bakker-Zierikzee AM, Tol EA, Kroes H, Kok FJ, Bindels JG.Faecal SIgA secretion in infants fed on pre- or probiotic in-fant formula. Pediatr Allergy Immunol 2006; 17: 134-40. 14.Köhler H, Donarski S, Stocks B, Parret A, Edwards C, Schro-ten H. Antibacterial characteristics in the feces of breast-fedand formula-fed infants during the first year of life. J Pedi-atr Gastroenterol Nutr 2002; 34: 188-93. 15.Kalliomäki M, Salminen S, Arvilommi H, Kero P, KoskinenP, Isolauri E. Probiotics in primary prevention of atopic di-sease: a randomised placebo-controlled trial. Lancet 2001;357: 1076-79. 16.Björkstén B. Allergy prevention. Interventions during preg-nancy and early infancy. Clin Rev Allergy Immunol 2004; 26:129-38. 17.Millar M, Wilks M, Costeloe K. Probiotics for preterm infants?Arch Dis Child Fetal Neonatal Ed 2003; 88: F354-358.18.Linskens RK, Huijsdens XW, Savelkoul PH, Vandenbroucke-Grauls CM, Meuwissen SG. The bacterial flora in inflamma-tory bowel disease: current insights in pathogenesis and theinfluence of antibiotics and probiotics. Scand J Gastroente-rol 2001; (Suppl): 29-40. 19.Rautava S, Ruuskanen O, Ouwehand A, Salminen S, Isolau-ri E. The hygiene hypothesis of atopic disease-an extended ver-sion. J Pediatr Gastroenterol Nutr 2004; 38: 378-88. 20.Kirjavainen PV, Arvola T, Salminen SJ, Isolauri E. Aberrantcomposition of gut microbiota of allergic infants: a target ofbifidobacterial therapy at weaning? Gut 2002; 51: 51-55. 21.Mohan R, Koebnick C, Schildt J, et al. Effects of Bifidobac-terium lactis Bb12 supplementation on intestinal microbiotaof preterm infants: a double-blind, placebo-controlled, ran-domized study. J Clin Microbiol 2006; 44: 4015-31. 22.Gill HS, Rutherfurd KJ, Cross ML. Dietary probiotic supp-lementation enhances natural killer cell activity in the elderly:an investigation of age-related immunological changes. J ClinImmunol 2001; 21: 264-71. 23.Ogawa T, Asai Y, Tamai R, et al. Natural killer cell activiti-es of synbiotic Lactobacillus casei ssp. casei in conjunctionwith dextran. Clin Exp Immunol 2006; 143: 103-109. 24.Rinne M, Kalliomaki M, Arvilommi H, Salminen S, IsolauriE. Effect of probiotics and breastfeeding on the bifidobacte-rium and lactobacillus/enterococcus microbiota and humo-ral immune responses. J Pediatr 2005; 147: 186-91. 25.Lin HC, Su BH, Chen AC, et al. Oral probiotics reduce theincidence and severity of necrotizing enterocolitis in very lowbirth weight infants. Pediatrics 2005; 115: 1-4. 26.Galdeano CM, Pergidon C. Role of viability of probiotic stra-ins in their persistence in the gut and in mucosal immune sti-mulation. J Appl Microbiol 2004; 97: 673-81.
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Details
| Primary Language | Turkish |
|---|---|
| Journal Section | makale |
| Authors | |
| Publication Date | May 5, 2016 |
| Published in Issue | Year 2016 Volume: 8 Issue: 3 |
