Clinicopathological Findings on Naturally Occurring Aspergillosis in Pigeons

Year 2013, Volume: 1 Issue: 1, 1 - 10, 30.04.2013

Özlem Özmen

Abstract

Aspergillosis is a serious fungal diseases and it affected all of the animals including birds. The aim of this study is to present clinicopathological findings of severe aspergillosis and treatment of the diseases in a pigeon flock. In this study, 1-1.5 month’s old 17 pigeons from a flock of 85 presented with symptoms of respiratory distress, inappetence, torticollis, incoordination and 20% mortality were examined macroscopically and microscopically. At necropsy granulomatous lesions were observed mainly in air sacs and lungs. Microscopic examination of the squeeze preparation of the air sacs and lungs revealed the presence of typical conidiophores of an Aspergillus sp. Histopathologically, necrosis with heterophil leukocyte, lymphocyte, macrophage and giant cells were observed in the granulomatous lesions. Although severe nervous symptoms were observed there were no macroscopical lesions seen in brains and cerebellums, slight gliosis was diagnosed at histopathological examinations. Immunohistochemical examination of central nervous system for Newcastle Disease was negative. Fungal agents were demonstrated in lesions in lungs and air sacs with periodic acid Schiff (PAS) methods. After diagnosis the tiny house were ventilated remained pigeons without neurological but with general symptoms were treated with 10.3 mg/kg itraconazole and multivitamin complexes. 

Keywords

Aspergillosis, airsacculitis, nervous symptoms, pigeon, treatment

Güvercinlerde Doğal Olarak Şekillenmiş Aspergilloziste Klinikopatolojik Bulgular

Abstract

Aspergillosis kuşlar dâhil bütün hayvanları etkileyen bir mantar hastalığıdır. Bu çalışmanın amacı bir güvercin sürüsünde karşılaşılan şiddetli bir aspergillozis hastalığında klinik ve patolojik bulguların incelenmesidir. Bu çalışmada, solunum yolu problemleri, iştahsızlık, tortikollis, inkoordinasyon ve %20 mortalitenin olduğu, 85 hayvanlık bir sürüden 1-1.5aylık, 17 güvercin
makroskobik ve mikroskobik olarak incelendi. Nekropside, hava keseleri ve akciğerlerde granülomatöz lezyonlar gözlendi. Akciğer ve hava keselerinden yapılan sürme preparatlarda tipik Aspergillus sp. konidioforları saptandı. Histopatolojik olarak granülomatöz lezyonlarda heterofil lökositler, lenfositler, makrofajlar ve dev hücreler gözlendi. Şiddetli sinirsel semptomlara rağmen beyin ve beyincikte makroskobik lezyon gözlenmedi, histopatolojik yoklamada hafif gliozis dikkati çekti. Merkezi sinir sisteminin Newcatle hastalığı yönünden yapılan immunhistokimyasal incelemesi negatifti. Fungal etken akciğer ve hava keselerinde periodic acid Schiff (PAS) method ile gösterildi. Teşhisten sonra kümes havalandırıldı ve sinirsel semptomu olmayan ancak genel semptomu bulunan güvercinler 10.3 mg/kg itraconazole ve multivitamin kompleksleriyle tedavi edildi.

Keywords

Aspergillosis, airsakkülitis, sinirsel semptomlar, güvercin, tedavi

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