Case Report
Year 2018,
Volume: 3 Issue: 1, 71 - 78, 30.06.2018
Abstract
Bu vaka raporunda 10 yaşlı, dişi, Setter ırkı, bir köpekte uterusta nadir
gözlenen osteoklast-benzeri dev hücreli tümör bildirilmiştir. Makroskobik
olarak 27x24x11 cm ölçülen tümöral kitle serviks tabanında yer alıyordu.
Histopatolojik olarak atipik iğ-küresel şekilli yüksek mitotik aktiviteye sahip
hücreler ile dağınık halde osteoklast benzeri çok çekirdekli dev hücreler
gözlendi. Tümör hücreleri vimentin, CD 117, LCA antikorları ile pozitif
boyandı. Bunun tersine, aynı hücreler sitokeratin, CD 34, S100 ve SMA
antikorları ile boyanmadı Bu bir köpeğin uterusunda ilk defa bildirilen malign
osteoklast-benzeri dev hücreli tümördür.
Keywords
References
- 1.Bennett JA, Sanada S, Selig MK, Hariri LP, Nielsen GP, Oliva E. Giant Cell Tumor of the Uterus. A Report of 3 Cases with a spectrum of morphologic features. Int J Gynecol Pathol. 2015; 34: 340-350.
- 2.Borg-Grech A, Morris JA, Eyden BP. Malignant osteoclastoma-like giant cell tumor of renal pelvis. Histopathology. 1987; 11: 415–425.
- 3.Chand CK, Bhardwaj LCRK, Rappai MTJ. Study of 7 cases of giant cell tumour of soft tissue. MJAFI. 2006; 62: 138-140.
- 4.Ford GH, Empson RN, Plopper CG, Brown PH. Giant cell tumour of soft part: a report of an equine and a feline case. Vet Pathol, 1975; 12: 428-433.
- 5.Hamir AN. Equine giant cell tumour of soft tissues. Cornell Vet, 1989; 79: 173-177.
- 6.Hazıroglu R, Kul O, Tunca R, Guvenc T. Osteoclast-like giant cell tumour arising from the kidney in a dog. Acta. Vet. Hung., 2005, 53, 225-230.
- 7.Manglik N, Sawicki J, Saad A, Fadare O, Soslow R, Liang SX. Giant cell tumor of uterus resembling osseous giant cell tumor. NTJ Surg Pathol. 2012; 6: 618-622.
- 8.Mannan R, Khanna M, Bhasin TS, Misra V, Singh PA. Undifferentiated carcinoma with osteoclast-like giant cell tumor of the pancreas: a discussion of rare entity in comparison with pleomorphic giant cell tumor of the pancreas. Indian. J Pathol. Microbiol. 2010; 53: 867-868.
- 9.Moll R, Lowe A, Laufer J, Franke WW: Cytokeratin 20 in human carcinomas. A new histodiagnostic marker detected by monoclonal antibodies. Am J Pathol. 1992; 140: 427-447.
- 10.O'connell JX, Wehrlı BM, Nielsen GP, Rosenberg AE. Giant cell tumors of soft tissue: a clinicopathologic study of 18 benign and malignant tumors. Am J Surg Pathol. 2000; 24: 386-395.
- 11.Oliveira AM, DeiiTos AP, Fletcher CDM, Nascimento AG. Primary giant cell tumor of soft tissues. A study of 22 cases. Am J Surg Pathol. 2000; 24: 248-256.
- 12.Sieinski W. Malignant giant-cell tumor associated with leiomyosarcoma of the uterus. Cancer. 1990; 65: 1838-1842.
- 13.Temesgen WM, Wachtel M, Dissanaike S. Osteoclastic giant cell tumor of the pancreas. Int J Surg, 2014; 5: 175-179.
- 14.Thomsen BW, Myers RK. Extraskeletal osteosarcoma of the mandibular salivary gland in a dog. Vet Pathol, 1999; 36: 71-73.
Year 2018,
Volume: 3 Issue: 1, 71 - 78, 30.06.2018
Abstract
References
- 1.Bennett JA, Sanada S, Selig MK, Hariri LP, Nielsen GP, Oliva E. Giant Cell Tumor of the Uterus. A Report of 3 Cases with a spectrum of morphologic features. Int J Gynecol Pathol. 2015; 34: 340-350.
- 2.Borg-Grech A, Morris JA, Eyden BP. Malignant osteoclastoma-like giant cell tumor of renal pelvis. Histopathology. 1987; 11: 415–425.
- 3.Chand CK, Bhardwaj LCRK, Rappai MTJ. Study of 7 cases of giant cell tumour of soft tissue. MJAFI. 2006; 62: 138-140.
- 4.Ford GH, Empson RN, Plopper CG, Brown PH. Giant cell tumour of soft part: a report of an equine and a feline case. Vet Pathol, 1975; 12: 428-433.
- 5.Hamir AN. Equine giant cell tumour of soft tissues. Cornell Vet, 1989; 79: 173-177.
- 6.Hazıroglu R, Kul O, Tunca R, Guvenc T. Osteoclast-like giant cell tumour arising from the kidney in a dog. Acta. Vet. Hung., 2005, 53, 225-230.
- 7.Manglik N, Sawicki J, Saad A, Fadare O, Soslow R, Liang SX. Giant cell tumor of uterus resembling osseous giant cell tumor. NTJ Surg Pathol. 2012; 6: 618-622.
- 8.Mannan R, Khanna M, Bhasin TS, Misra V, Singh PA. Undifferentiated carcinoma with osteoclast-like giant cell tumor of the pancreas: a discussion of rare entity in comparison with pleomorphic giant cell tumor of the pancreas. Indian. J Pathol. Microbiol. 2010; 53: 867-868.
- 9.Moll R, Lowe A, Laufer J, Franke WW: Cytokeratin 20 in human carcinomas. A new histodiagnostic marker detected by monoclonal antibodies. Am J Pathol. 1992; 140: 427-447.
- 10.O'connell JX, Wehrlı BM, Nielsen GP, Rosenberg AE. Giant cell tumors of soft tissue: a clinicopathologic study of 18 benign and malignant tumors. Am J Surg Pathol. 2000; 24: 386-395.
- 11.Oliveira AM, DeiiTos AP, Fletcher CDM, Nascimento AG. Primary giant cell tumor of soft tissues. A study of 22 cases. Am J Surg Pathol. 2000; 24: 248-256.
- 12.Sieinski W. Malignant giant-cell tumor associated with leiomyosarcoma of the uterus. Cancer. 1990; 65: 1838-1842.
- 13.Temesgen WM, Wachtel M, Dissanaike S. Osteoclastic giant cell tumor of the pancreas. Int J Surg, 2014; 5: 175-179.
- 14.Thomsen BW, Myers RK. Extraskeletal osteosarcoma of the mandibular salivary gland in a dog. Vet Pathol, 1999; 36: 71-73.
There are 14 citations in total.
Details
| Primary Language | English |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Case Reports |
| Authors | |
| Publication Date | June 30, 2018 |
| Submission Date | April 6, 2018 |
| Published in Issue | Year 2018 Volume: 3 Issue: 1 |
