Investigation of plasma pepsinogen level in calves with abomasal distention

Year 2022, Volume: 7 Issue: 3, 155 - 160, 31.12.2022

Nuri Mamak , Ramazan Yıldız , Halil İbrahim Gökçe , Türker Atcalı

https://doi.org/10.24880/maeuvfd.1110471

Abstract

The aims of the present study was to determine whether or not abomasal damages occurs in calves with abdominal distention using by plasma pepsinogen levels and the positivity of the fecal occult blood test (FOBT). In the study, 30 calves with abdominal distention (distention group) and 15 clinically healthy calves (control group), aged between 1-90 days, were used. Collected plasma samples of all the calves were used to determine plasma pepsinogen levels, using bovine specific ELISA. Fresh stool samples were also taken from the rectum of all the calves and used to determine occult blood in the samples. In the study, melena and occult blood were detected in 11 and 19 of the stool samples, respectively. The plasma pepsinogen levels of calves with abdominal distention (18.06±7.78 ng/ml) were significatly high compared to those of control group (6.70±2.08 ng/ml), (p<0.001). In addition, plasma pepsinogen levels were higher in melena (+) animals than both FOBT (+) and control animals (p<0.001). It is suggestive that plasma pepsinogen levels can be used to determine abomasal damage in calves with gastrointestinal problems, especially with abdominal distention. It can be also useful biomarker to determine the severity of abomasal bleeding and therefore the severity of abomasal damage in calves.

Keywords

Abomasal distention, abomasum ulceration, pepsinogen, calf

Project Number

Proje No: 0524-MP-18

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