A Chronic Myeloid Leukemia Case Diagnosed Following Acute Kidney İnjury Event

Year 2022, Volume: 14 Issue: 2, 43 - 46, 31.08.2022

Ayşe Nur Küçükali Kenan , Fatih Öner Kaya , Figen Atalay , Itır Yeğenağa

https://doi.org/10.35514/mtd.2022.69

Abstract

A chronic myeloid leukemia (CML) case following acute kidney injury (AKI) was reported here.
80 year old man, admitted to the clinic with oliguria and increasing in serum urea and creatinine levels. He was diagnosed as acute kidney injury (AKI) and treated supportively, but recovered partly; no renal replacement therapy was required. Four months later he was referred to the clinic again because of significant, persistent leukocytosis; after peripheral blood smear, bone marrow biopsy and BCR-ABL gene scanning examination, he was diagnosed as chronic myeloid leukemia.

Keywords

Acute Kidney Injury, Chronic Myeloid Leukemia, BCR-ABL Gene, KDIGO Criteria

Akut Böbrek Hasarını Takiben Tanı Konan Kronik Miyeloid Lösemi Olgusu

Abstract

Bu yazıda akut böbrek hasarını (AKI) takiben tanı alan bir kronik myeloid lösemi (KML) vakası bildirilmiştir.
80 yaşında erkek hasta, oligüri ve serum kreatinin düzeylerinde yükselme ile kliniğe başvurdu. Akut böbrek hasarı (AKI) teşhisi kondu ve destekleyici tedavi verildi,kısmen iyileşme sağlandı,renal replasman tedavisi gerekmedi. Dört ay sonra persistan lökositoz nedeniyle tekrar kliniğe başvurdu; periferik yayma,kemik iliği biyopsisi ve BCR-ABL gen tarama incelemesi sonrasında kronik myeloid lösemi tanısı kondu.

Keywords

Akut Böbrek Hasarı, Kronik Myeloid Lösemi, BCR-ABL Geni, KDIGO Kriterleri

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