Case Report
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Year 2024, Volume: 37 Issue: 3, 379 - 383, 30.10.2024
https://doi.org/10.5472/marumj.1572504

Abstract

References

  • Hakim FA, Tleyjeh IM. Severe adenovirus pneumonia in immunocompetent adults: a case report and review of the literature. Eur J Clin Microbiol Infect Dis 2008;27:153-8. doi: 10.1007/s10096.007.0416-z.
  • Lynch JP 3rd, Fishbein M, Echavarria M. Adenovirus. Semin Respir Crit Care Med 2011 ;32:494-511. doi: 10.1055/s- 0031.128.3287.
  • Pham TT, Burchette JL Jr, Hale LP. Fatal disseminated adenovirus infections in immunocompromised patients. Am J Clin Pathol 2003;120:575-83. doi: 10.1309/AWXD-GNC5- D70E-N7YT.
  • Hijikata N, Takayanagi N, Sato S, et al. Adenovirus pneumonia in an immunocompetent adult. J Infect Chemother 2012;18:780-5. doi: 10.1007/s10156.012.0367-x.
  • Rynans S, Dzieciątkowski T, Młynarczyk G. Zakażenia. Adenovirus infection in immunocompromised patients. Postepy Hig Med Dosw (Polish) 2013;67:964-72. doi: 10.5604/17322.693.1066199.
  • Tan D, Zhu H, Fu Y, et.al. Severe community-acquired pneumonia caused by human adenovirus in immunocompetent adults: A multicenter case series. PLoS One 2016 ;11:e0151199. doi: 10.1371/journal.pone.0151199.
  • Lion T. Adenovirus infections in immunocompetent and immunocompromised patients. Clin Microbiol Rev 2014;27:441-62. doi: 10.1128/CMR.00116-13.
  • DeCaprio JA. How the Rb tumor suppressor structure and function was revealed by the study of Adenovirus and SV40. Virology 2009;384:274-84. doi: 10.1016/j.virol.2008.12.010.
  • Chmielewicz B, Benzler J, Pauli G, Krause G, Bergmann F, Schweiger B. Respiratory disease caused by a species B2 adenovirus in a military camp in Turkey. J Med Virol 2005; 77:232-7. doi:10.1002/jmv.20441.
  • Cederwall S, Påhlman LI. Respiratory adenovirus infections in immunocompetent and immunocompromised adult patients. Epidemiol Infect 2020;147:e328. doi: 10.1017/ S095.026.8819002176.
  • Febbo J, Revels J, Ketai L. Viral pneumonias. Radiol Clin North Am 2022;60:383-97. doi: 10.1016/j.rcl.2022.01.010.
  • Zhang P, Liu M, Zhang L, et.al. Clinical and CT findings of adenovirus pneumonia in immunocompetent adults. Clin Respir J 2021;15:1343-51. doi: 10.1111/crj.13439.
  • Cillóniz C, Pericàs JM, Rojas JR, Torres A. Severe ınfections due to respiratory viruses. Semin Respir Crit Care Med 2022;43:60-74. doi: 10.1055/s-0041.174.0982.
  • Aggarwal G, Lippi G, Lavie CJ, Henry BM, Sanchis-Gomar F. Diabetes mellitus association with coronavirus disease 2019 (COVID-19) severity and mortality: A pooled analysis. J Diabetes 2020;12:851-5. doi: 10.1111/1753-0407.13091.
  • Robertson RP. Antagonist: diabetes and insulin resistance— philosophy, science, and the multiplier hypothesis. J Lab Clin Med 1995;125:560-4.
  • Davies MJ, Aroda VR, Collins BS, et al. Management of hyperglycaemia in type 2 diabetes, 2022. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetologia 2022;65:1925-66. doi: 10.1007/s00125.022.05787-2.
  • Petrelli F, Grappasonni I, Nguyen CTT, et al. Metformin and COVID-19: a systematic review of systematic reviews with meta-analysis. Acta Biomed 2023;94:e2023138. doi: 10.23750/ abm.v94iS3.14405.
  • Raina MacIntyre C, Chughtai AA, Zhang Y, et al. Viral and bacterial upper respiratory tract infection in hospital health care workers over time and association with symptoms. BMC Infect Dis 2017;17:553. doi: 10.1186/s12879.017.2649-5.
  • Yoon BW, Song YG, Lee SH. Severe community-acquired adenovirus pneumonia treated with oral ribavirin: a case report. BMC Res Notes 2017 ;10:47. doi: 10.1186/ s13104.016.2370-2.
  • Zhao J, Yap A, Wu E, Low CY, Yap J. Severe community acquired adenovirus pneumonia in an immunocompetent host successfully treated with IV Cidofovir. Respir Med Case Rep 2020;30:101037. doi: 10.1016/j.rmcr.2020.101037.

Adenovirus pneumonia in an immunocompetent patient : A case report

Year 2024, Volume: 37 Issue: 3, 379 - 383, 30.10.2024
https://doi.org/10.5472/marumj.1572504

Abstract

Adenoviruses are viruses that typically cause mild infections involving the upper or lower respiratory tract, gastrointestinal tract, or
conjunctiva in children and immunocompromised patients. Severe pneumonia progressing to respiratory failure is very rare in healthy
adults without underlying immunodeficiency.
In this article, a case of fulminant pneumonia caused by adenovirus in a 26-year-old immunocompetent male patient is presented. The
patient, a pediatric resident, applied to our emergency department with cough, pharyngitis, myalgia and fever. He was hospitalized
due to the development of tachypnea, dyspnea and somnolence during follow up. Adenovirus was isolated from the nasopharyngeal
swab and stool of the patient who developed hypoxemia and had infiltrates on the chest radiograph. The case, that got well and was
discharged after an 11-day hospitalization, has been discussed in line with previous studies.

References

  • Hakim FA, Tleyjeh IM. Severe adenovirus pneumonia in immunocompetent adults: a case report and review of the literature. Eur J Clin Microbiol Infect Dis 2008;27:153-8. doi: 10.1007/s10096.007.0416-z.
  • Lynch JP 3rd, Fishbein M, Echavarria M. Adenovirus. Semin Respir Crit Care Med 2011 ;32:494-511. doi: 10.1055/s- 0031.128.3287.
  • Pham TT, Burchette JL Jr, Hale LP. Fatal disseminated adenovirus infections in immunocompromised patients. Am J Clin Pathol 2003;120:575-83. doi: 10.1309/AWXD-GNC5- D70E-N7YT.
  • Hijikata N, Takayanagi N, Sato S, et al. Adenovirus pneumonia in an immunocompetent adult. J Infect Chemother 2012;18:780-5. doi: 10.1007/s10156.012.0367-x.
  • Rynans S, Dzieciątkowski T, Młynarczyk G. Zakażenia. Adenovirus infection in immunocompromised patients. Postepy Hig Med Dosw (Polish) 2013;67:964-72. doi: 10.5604/17322.693.1066199.
  • Tan D, Zhu H, Fu Y, et.al. Severe community-acquired pneumonia caused by human adenovirus in immunocompetent adults: A multicenter case series. PLoS One 2016 ;11:e0151199. doi: 10.1371/journal.pone.0151199.
  • Lion T. Adenovirus infections in immunocompetent and immunocompromised patients. Clin Microbiol Rev 2014;27:441-62. doi: 10.1128/CMR.00116-13.
  • DeCaprio JA. How the Rb tumor suppressor structure and function was revealed by the study of Adenovirus and SV40. Virology 2009;384:274-84. doi: 10.1016/j.virol.2008.12.010.
  • Chmielewicz B, Benzler J, Pauli G, Krause G, Bergmann F, Schweiger B. Respiratory disease caused by a species B2 adenovirus in a military camp in Turkey. J Med Virol 2005; 77:232-7. doi:10.1002/jmv.20441.
  • Cederwall S, Påhlman LI. Respiratory adenovirus infections in immunocompetent and immunocompromised adult patients. Epidemiol Infect 2020;147:e328. doi: 10.1017/ S095.026.8819002176.
  • Febbo J, Revels J, Ketai L. Viral pneumonias. Radiol Clin North Am 2022;60:383-97. doi: 10.1016/j.rcl.2022.01.010.
  • Zhang P, Liu M, Zhang L, et.al. Clinical and CT findings of adenovirus pneumonia in immunocompetent adults. Clin Respir J 2021;15:1343-51. doi: 10.1111/crj.13439.
  • Cillóniz C, Pericàs JM, Rojas JR, Torres A. Severe ınfections due to respiratory viruses. Semin Respir Crit Care Med 2022;43:60-74. doi: 10.1055/s-0041.174.0982.
  • Aggarwal G, Lippi G, Lavie CJ, Henry BM, Sanchis-Gomar F. Diabetes mellitus association with coronavirus disease 2019 (COVID-19) severity and mortality: A pooled analysis. J Diabetes 2020;12:851-5. doi: 10.1111/1753-0407.13091.
  • Robertson RP. Antagonist: diabetes and insulin resistance— philosophy, science, and the multiplier hypothesis. J Lab Clin Med 1995;125:560-4.
  • Davies MJ, Aroda VR, Collins BS, et al. Management of hyperglycaemia in type 2 diabetes, 2022. A consensus report by the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD). Diabetologia 2022;65:1925-66. doi: 10.1007/s00125.022.05787-2.
  • Petrelli F, Grappasonni I, Nguyen CTT, et al. Metformin and COVID-19: a systematic review of systematic reviews with meta-analysis. Acta Biomed 2023;94:e2023138. doi: 10.23750/ abm.v94iS3.14405.
  • Raina MacIntyre C, Chughtai AA, Zhang Y, et al. Viral and bacterial upper respiratory tract infection in hospital health care workers over time and association with symptoms. BMC Infect Dis 2017;17:553. doi: 10.1186/s12879.017.2649-5.
  • Yoon BW, Song YG, Lee SH. Severe community-acquired adenovirus pneumonia treated with oral ribavirin: a case report. BMC Res Notes 2017 ;10:47. doi: 10.1186/ s13104.016.2370-2.
  • Zhao J, Yap A, Wu E, Low CY, Yap J. Severe community acquired adenovirus pneumonia in an immunocompetent host successfully treated with IV Cidofovir. Respir Med Case Rep 2020;30:101037. doi: 10.1016/j.rmcr.2020.101037.
There are 20 citations in total.

Details

Primary Language English
Subjects Surgery (Other)
Journal Section Case Reports
Authors

Duygu Vezir 0000-0001-6146-2610

Özlem Alkan This is me 0009-0009-2519-0764

Nihal Merve Çankaya This is me 0000-0003-1675-6710

Zekaver Odabaşı This is me 0000-0001-8091-6999

Emel Eryüksel 0000-0002-2194-8066

Publication Date October 30, 2024
Published in Issue Year 2024 Volume: 37 Issue: 3

Cite

APA Vezir, D., Alkan, Ö., Çankaya, N. M., Odabaşı, Z., et al. (2024). Adenovirus pneumonia in an immunocompetent patient : A case report. Marmara Medical Journal, 37(3), 379-383. https://doi.org/10.5472/marumj.1572504
AMA Vezir D, Alkan Ö, Çankaya NM, Odabaşı Z, Eryüksel E. Adenovirus pneumonia in an immunocompetent patient : A case report. Marmara Med J. October 2024;37(3):379-383. doi:10.5472/marumj.1572504
Chicago Vezir, Duygu, Özlem Alkan, Nihal Merve Çankaya, Zekaver Odabaşı, and Emel Eryüksel. “Adenovirus Pneumonia in an Immunocompetent Patient : A Case Report”. Marmara Medical Journal 37, no. 3 (October 2024): 379-83. https://doi.org/10.5472/marumj.1572504.
EndNote Vezir D, Alkan Ö, Çankaya NM, Odabaşı Z, Eryüksel E (October 1, 2024) Adenovirus pneumonia in an immunocompetent patient : A case report. Marmara Medical Journal 37 3 379–383.
IEEE D. Vezir, Ö. Alkan, N. M. Çankaya, Z. Odabaşı, and E. Eryüksel, “Adenovirus pneumonia in an immunocompetent patient : A case report”, Marmara Med J, vol. 37, no. 3, pp. 379–383, 2024, doi: 10.5472/marumj.1572504.
ISNAD Vezir, Duygu et al. “Adenovirus Pneumonia in an Immunocompetent Patient : A Case Report”. Marmara Medical Journal 37/3 (October 2024), 379-383. https://doi.org/10.5472/marumj.1572504.
JAMA Vezir D, Alkan Ö, Çankaya NM, Odabaşı Z, Eryüksel E. Adenovirus pneumonia in an immunocompetent patient : A case report. Marmara Med J. 2024;37:379–383.
MLA Vezir, Duygu et al. “Adenovirus Pneumonia in an Immunocompetent Patient : A Case Report”. Marmara Medical Journal, vol. 37, no. 3, 2024, pp. 379-83, doi:10.5472/marumj.1572504.
Vancouver Vezir D, Alkan Ö, Çankaya NM, Odabaşı Z, Eryüksel E. Adenovirus pneumonia in an immunocompetent patient : A case report. Marmara Med J. 2024;37(3):379-83.