Synthesis and antiviral activity evaluation of some new cyclohexylidenehydrazide derivatives of 1,3-thiazole core

Year 2016, Volume: 20 Issue: 2, 207 - 215, 18.03.2016

Nuray Ulusoy , Erkan Pehlivan Zeynep Halamoğlu Ayşe Kocabalkanlı

Abstract

ABSTRACT

Some novel cyclohexylidenehydrazide derivatives carrying five membered heterocyclic ring, 1,3-thiazole were synthesized to investigate their antiviral (including anti-HIV) activity against diverse DNA and RNA viruses in CRFK, HeLa, HEL, MDCK, Vero and MT4 cell cultures. None of the compounds was active against any of the DNA or RNA viruses at 100 μM.

Keywords

1, 3-Thiazole, cyclohexylidenehydrazide, antiviral activity

Synthesis and antiviral activity evaluation of some new cyclohexylidenehydrazide derivatives of 1,3-thiazole core

Abstract

Nuray Ulusoy Güzeldemirci, Erkan Pehlivan, Zeynep Halamoğlu, Ayşe Kocabalkanlı Istanbul University, Faculty of Pharmacy, Department of Pharmaceutical Chemistry, 34116 Istanbul, Turkey

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