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Clinicopathological Profile of Thyroid Carcinomas: A 10-Year Experience in a Tertiary Care Institute

Year 2020, Volume: 6 Issue: 1, 24 - 27, 30.04.2020
https://doi.org/10.19127/mbsjohs.646535

Abstract

Objective: Thyroid gland is an important endocrine gland and thyroid cancers (TC) are the most noteworthy disease of the thyroid gland. Although thyroid surgery is performed for most particularly for malignancy, thyroidectomies still maintain a large part of surgical operations. We aimed to investigate the incidence and subtypes of the thyroid cancers in present study, with our 10 years experience of thyroid surgery.
Methods: Data of patients who underwent thyroidectomy were retrospectively analyzed. The patients who underwent bilateral total thyroidectomy were included to the study. Patients’ age, gender and histopathological results were recorded. According to the histopathological reports we divided the patients into two groups either as benign or malignant.
Results: A total of 3632 patients were included in the study. 2999 (82.6%) patients were in benign group and 633(17.4%) patients were in malignant group. The subtypes of malignant tumors were papillary carcinoma in 591 (93.4%), medullary carcinoma in 16 (2.5%), follicular carcinoma in 14 (2.2%), oncocytic (hurtle cell) carcinoma in 7 (1.1%) and undifferentiated (anaplastic) in 5(0.8%) of the cases.
Conclusion: Incidental thyroid cancers are not a rare entity after pathological examination of thyroid specimen after surgery. Therefore, we suggest careful evaluation and bilateral leb lobectomy ectomy in surgical treatment of thyroid conditions

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References

  • Akgun Y, Ongoren A, Kuru S, Acar E, Cengiz A, & Gulhan D. Tetany after thyroid surgery. Turkish Medical Journal, 2007;1, 80-85.
  • Are C, & Shaha A.R. Anaplastic thyroid carcinoma: biology, pathogenesis, prognostic factors, and treatment approaches. Annals of surgical oncology, 2006;13(4), 453-464.
  • Benek S, Kocakusak A, Ozer B, Kizilkaya M.C, Erozgen, F, Ciftci F, Tatar C. The Ever-Changing Configuration of the Completion Thyroidectomy in the Last Decade. Haseki Tip Bulteni, 2015;53(3).
  • Davies L, & Welch H.G. Current thyroid cancer trends in the United States. JAMA Otolaryngology–Head & Neck Surgery, 2014;140(4), 317-322.
  • Efremidou E.I, Papageorgiou M.S, Liratzopoulos N, & Manolas K.J. The efficacy and safety of total thyroidectomy in the management of benign thyroid disease: a review of 932 cases. Canadian Journal of Surgery, 2009;52(1), 39.
  • Erbil Y, Barbaros U, Salmaslıoglu A, Yanık B.T, Bozbora A., & Ozarmagan, S. The advantage of near-total thyroidectomy to avoid postoperative hypoparathyroidism in benign multinodular goiter. Langenbeck's archives of surgery, 2006;391(6), 567-573.
  • Grigsby P.W, Gal‐or A, Michalski J.M, & Doherty G.M. Childhood and adolescent thyroid carcinoma. Cancer: Interdisciplinary International Journal of the American Cancer Society, 2002;95(4), 724-729.
  • Hu D, Zhou J, He W, Peng J, Cao Y, Ren H, Xiao Q. Risk factors of lateral lymph node metastasis in cN0 papillary thyroid carcinoma. World journal of surgical oncology, 2018;16(1), 30.
  • Jemal A., Siegel R, Xu J, & Ward E. Cancer statistics, 2010. CA: a cancer journal for clinicians, 2010;60(5), 277-300.
  • Lee J.-H, & Shin S.W. Overdiagnosis and screening for thyroid cancer in Korea. The Lancet, 2014;384(9957), 1848.
  • Lefevre J.H., Tresallet C, Leenhardt L., Jublanc C., Chigot J.P., & Menegaux F. Reoperative surgery for thyroid disease. Langenbeck's archives of surgery, 2007;392(6), 685-691.
  • Magreni A, Bann D.V, Schubart J.R., & Goldenberg D. The effects of race and ethnicity on thyroid cancer incidence. JAMA Otolaryngology–Head & Neck Surgery, 2015;141(4), 319-323.
  • Nickel B, Tan T., Cvejic E, Baade P, McLeod D.S., Pandeya, N., Jordan, S. Health-Related Quality of Life After Diagnosis and Treatment of Differentiated Thyroid Cancer and Association With Type of Surgical Treatment. JAMA Otolaryngology–Head & Neck Surgery, 2019;145(3), 231-238. Ohtsuru A, Midorikawa S, Ohira T., Suzuki S., Takahashi H., Murakami M., Suzuki S. Incidence of thyroid cancer among children and young adults in Fukushima, Japan, screened with 2 rounds of ultrasonography within 5 years of the 2011 Fukushima Daiichi Nuclear Power Station accident. JAMA Otolaryngology–Head & Neck Surgery, 2019;145(1), 4-11.
  • Prades J.M., Dumollard J.M., Timoshenko A, Chelikh L, Michel F, Estour B, & Martin C. Multinodular goiter: surgical management and histopathological findings. European archives of oto-rhino-laryngology, 2002;259(4), 217-221.
Year 2020, Volume: 6 Issue: 1, 24 - 27, 30.04.2020
https://doi.org/10.19127/mbsjohs.646535

Abstract

References

  • Akgun Y, Ongoren A, Kuru S, Acar E, Cengiz A, & Gulhan D. Tetany after thyroid surgery. Turkish Medical Journal, 2007;1, 80-85.
  • Are C, & Shaha A.R. Anaplastic thyroid carcinoma: biology, pathogenesis, prognostic factors, and treatment approaches. Annals of surgical oncology, 2006;13(4), 453-464.
  • Benek S, Kocakusak A, Ozer B, Kizilkaya M.C, Erozgen, F, Ciftci F, Tatar C. The Ever-Changing Configuration of the Completion Thyroidectomy in the Last Decade. Haseki Tip Bulteni, 2015;53(3).
  • Davies L, & Welch H.G. Current thyroid cancer trends in the United States. JAMA Otolaryngology–Head & Neck Surgery, 2014;140(4), 317-322.
  • Efremidou E.I, Papageorgiou M.S, Liratzopoulos N, & Manolas K.J. The efficacy and safety of total thyroidectomy in the management of benign thyroid disease: a review of 932 cases. Canadian Journal of Surgery, 2009;52(1), 39.
  • Erbil Y, Barbaros U, Salmaslıoglu A, Yanık B.T, Bozbora A., & Ozarmagan, S. The advantage of near-total thyroidectomy to avoid postoperative hypoparathyroidism in benign multinodular goiter. Langenbeck's archives of surgery, 2006;391(6), 567-573.
  • Grigsby P.W, Gal‐or A, Michalski J.M, & Doherty G.M. Childhood and adolescent thyroid carcinoma. Cancer: Interdisciplinary International Journal of the American Cancer Society, 2002;95(4), 724-729.
  • Hu D, Zhou J, He W, Peng J, Cao Y, Ren H, Xiao Q. Risk factors of lateral lymph node metastasis in cN0 papillary thyroid carcinoma. World journal of surgical oncology, 2018;16(1), 30.
  • Jemal A., Siegel R, Xu J, & Ward E. Cancer statistics, 2010. CA: a cancer journal for clinicians, 2010;60(5), 277-300.
  • Lee J.-H, & Shin S.W. Overdiagnosis and screening for thyroid cancer in Korea. The Lancet, 2014;384(9957), 1848.
  • Lefevre J.H., Tresallet C, Leenhardt L., Jublanc C., Chigot J.P., & Menegaux F. Reoperative surgery for thyroid disease. Langenbeck's archives of surgery, 2007;392(6), 685-691.
  • Magreni A, Bann D.V, Schubart J.R., & Goldenberg D. The effects of race and ethnicity on thyroid cancer incidence. JAMA Otolaryngology–Head & Neck Surgery, 2015;141(4), 319-323.
  • Nickel B, Tan T., Cvejic E, Baade P, McLeod D.S., Pandeya, N., Jordan, S. Health-Related Quality of Life After Diagnosis and Treatment of Differentiated Thyroid Cancer and Association With Type of Surgical Treatment. JAMA Otolaryngology–Head & Neck Surgery, 2019;145(3), 231-238. Ohtsuru A, Midorikawa S, Ohira T., Suzuki S., Takahashi H., Murakami M., Suzuki S. Incidence of thyroid cancer among children and young adults in Fukushima, Japan, screened with 2 rounds of ultrasonography within 5 years of the 2011 Fukushima Daiichi Nuclear Power Station accident. JAMA Otolaryngology–Head & Neck Surgery, 2019;145(1), 4-11.
  • Prades J.M., Dumollard J.M., Timoshenko A, Chelikh L, Michel F, Estour B, & Martin C. Multinodular goiter: surgical management and histopathological findings. European archives of oto-rhino-laryngology, 2002;259(4), 217-221.
There are 14 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Research articles
Authors

Bahri Ozer 0000-0002-4326-2102

Oğuz Catal This is me 0000-0002-4067-251X

Songül Peltek Ozer This is me 0000-0001-7334-219X

Mustafa Sit This is me 0000-0002-7475-7298

Hayri Erkol This is me 0000-0002-1426-0247

Publication Date April 30, 2020
Published in Issue Year 2020 Volume: 6 Issue: 1

Cite

Vancouver Ozer B, Catal O, Peltek Ozer S, Sit M, Erkol H. Clinicopathological Profile of Thyroid Carcinomas: A 10-Year Experience in a Tertiary Care Institute. Mid Blac Sea J Health Sci. 2020;6(1):24-7.

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