Review
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Year 2021, Volume: 7 Issue: 1, 154 - 162, 30.04.2021
https://doi.org/10.19127/mbsjohs.824473

Abstract

References

  • 1. Tural S, Koca I. Physico-chemical and antioxidant properties of Cornelian cherry fruits (Cornus mas L.) grown in Turkey. Sci Hortic (Amsterdam). 2008;116(4):362–366. https://doi.org/10.1016/j.scienta.2008.02.003.
  • 2. Benzie IFF. Evolution of dietary antioxidants. Comp Biochem Physiol Part A Mol Integr Physiol. 2003;136(1):113–126. https://doi.org/10.1016/S1095-6433(02)00368-9.
  • 3. Pisoschi AM, Pop A, Iordache F, Stanca L, Predoi G, Serban AI. Oxidative stress mitigation by antioxidants - An overview on their chemistry and influences on health status. Eur J Med Chem. 2021;209:112891. https://doi.org/10.1016/j.ejmech.2020.112891.
  • 4. Seeram NP, Schutzki R, Chandra A, Nair MG. Characterization, Quantification, and Bioactivities of Anthocyanins in Cornus Species. J Agric Food Chem. 2002;50(9):2519–2523. https://doi.org/10.1021/jf0115903.
  • 5. Ercişli S. Cornelian cherry Germplasm Resources of Turkey. J Fruit Ornam Plant Res. 2004;12:87–92.
  • 6. Klimenko S. The Cornelian cherry (Cornus mas L.): collection, preservation, and utilization of genetic resources. J Fruit Ornam Plant Res. 2004;12:93–98. 7. Wyndham R. Cranberry juice and urinary tract infections. Med Today. 2006;7(5):72–73.
  • 8. Badalica-Petrescu M, Dragan S, Ranga F, Fetea F, Socaciu C. Comparative HPLC-DAD-ESI(+)MS Fingerprint and Quantification of Phenolic and Flavonoid Composition of Aqueous Leaf Extracts of Cornus mas and Crataegus monogyna, in Relation to Their Cardiotonic Potential. Not Bot Horti Agrobot Cluj-Napoca. 2014;42(1):9–18. https://doi.org/10.15835/nbha4219270.
  • 9. Drkenda P, Spahić A, Begić-Akagić A, vd. Pomological characteristics of some autochthonous genotypes of Cornelian cherry (Cornus mas L.) in Bosnia and Herzegovina. Erwerbs-obstbau. 2014;56(2):59–66.
  • 10. Milenković-Anđelković AS, Anđelković MZ, Radovanović AN, Radovanović BC, Nikolić V. Phenol composition, DPPH radical scavenging and antimicrobial activity of Cornelian cherry (Cornus mas) fruit and leaf extracts. Hem Ind. 2015;69(4):331–337.
  • 11. Pawlowska AM, Camangi F, Braca A. Quali-quantitative analysis of flavonoids of Cornus mas L.(Cornaceae) fruits. Food Chem. 2010;119(3):1257–1261.
  • 12. Rudrapaul P, Kyriakopoulos AM, De UC, Zoumpourlis V, Dinda B. New flavonoids from the fruits of Cornus mas, Cornaceae. Phytochem Lett. 2015;11:292–295. https://doi.org/10.1016/j.phytol.2015.01.011.
  • 13. Sozański T, Kucharska AZ, Szumny A, vd. The protective effect of the Cornus mas fruits (cornelian cherry) on hypertriglyceridemia and atherosclerosis through PPARα activation in hypercholesterolemic rabbits. Phytomedicine. 2014;21(13):1774–1784. https://doi.org/10.1016/j.phymed.2014.09.005.
  • 14. Behrangi N, Ghafoori H, Farahmand Z, Khani EM, Sanati MH. Comparison among Cornelian cherry and <i>Prunus cerasus</i> According to Phenolic Content and Antioxidant Capacity by Three Various Methods of Extraction. Food Nutr Sci. 2015;06(12):1166–1173. https://doi.org/10.4236/fns.2015.612122.
  • 15. Krivoruchko E V. Carboxylic Acids from Cornus mas. Chem Nat Compd. 2014;50(1):112–113. https://doi.org/10.1007/s10600-014-0879-y.
  • 16. Szumny D, Sozański T, Kucharska AZ, vd. Application of Cornelian cherry iridoid-polyphenolic fraction and loganic acid to reduce intraocular pressure. Evidence-Based Complement Altern Med. 2015;2015. 17. Horváth G, Turcsi E, Molnár P, Szabó LG, Deli J. Isolation and identification of carotenoids in the fruit of Cornelian cherry (Cornus mas L.). Planta Med. 2007;73(09):P_286.
  • 18. Zargari A. Iranian medicinal plants. Tehran Tehran Univ Publ. 1997.
  • 19. PANTELIDIS G, VASILAKAKIS M, MANGANARIS G, DIAMANTIDIS G. Antioxidant capacity, phenol, anthocyanin and ascorbic acid contents in raspberries, blackberries, red currants, gooseberries and Cornelian cherries. Food Chem. 2007;102(3):777–783. https://doi.org/10.1016/j.foodchem.2006.06.021.
  • 20. Popović BM, Štajner D, Slavko K, Sandra B. Antioxidant capacity of Cornelian cherry (Cornus mas L.) – Comparison between permanganate reducing antioxidant capacity and other antioxidant methods. Food Chem. 2012;134(2):734–741. https://doi.org/10.1016/j.foodchem.2012.02.170.
  • 21. Stankovic MS, Zia-Ul-Haq M, Bojovic BM, Topuzovic MD. Total phenolics, flavonoid content and antioxidant power of leaf, flower and fruits from Cornelian cherry (Cornus mas L.). Bulg J Agric Sci. 2014;20(2014):358–363.
  • 22. Demir F, Hakki Kalyoncu İ. Some nutritional, pomological and physical properties of Cornelian cherry (Cornus mas L.). J Food Eng. 2003;60(3):335–341. https://doi.org/https://doi.org/10.1016/S0260-8774(03)00056-6.
  • 23. Dinda B, Kyriakopoulos AM, Dinda S, vd. Cornus mas L. (cornelian cherry), an important European and Asian traditional food and medicine: Ethnomedicine, phytochemistry and pharmacology for its commercial utilization in drug industry. J Ethnopharmacol. 2016;193:670–690. https://doi.org/10.1016/j.jep.2016.09.042.
  • 24. Lewis WH, Elvin-Lewis MPF. Medical botany: plants affecting human health. John Wiley & Sons; 2003.
  • 25. Polatoğlu B, Beşe AV. Sun Drying of Cornelian cherry Fruits (Cornus mas L.). Erzincan Univ J Sci Technol. 2017;10(1):68–77. https://doi.org/10.18185/erzifbed.289008.
  • 26. Zlatković BK, Bogosavljević SS, Radivojević AR, Pavlović MA. Traditional use of the native medicinal plant resource of Mt. Rtanj (Eastern Serbia): Ethnobotanical evaluation and comparison. J Ethnopharmacol. 2014;151(1):704–713.
  • 27. Celik S, Bakırcı I, Şat IG. Physicochemical and organoleptic properties of yogurt with Cornelian cherry paste. Int J Food Prop. 2006;9(3):401–408.
  • 28. Egea T, Signorini MA, Bruschi P, vd. Spirits and liqueurs in European traditional medicine: Their history and ethnobotany in Tuscany and Bologna (Italy). J Ethnopharmacol. 2015;175:241–255.
  • 29. Hsu P-C, Tsai Y-T, Lai J-N, Wu C-T, Lin S-K, Huang C-Y. Integrating traditional Chinese medicine healthcare into diabetes care by reducing the risk of developing kidney failure among type 2 diabetic patients: a population-based case control study. J Ethnopharmacol. 2014;156:358–364.
  • 30. Reich L. Cornelian cherry from the shores of Ancient Greece. Mag Arnold Arbor. 1996;56:2–7.
  • 31. Martinović A, Cavoski I. The exploitation of Cornelian cherry (Cornus mas L.) cultivars and genotypes from Montenegro as a source of natural bioactive compounds. Food Chem. 2020;318:126549. https://doi.org/https://doi.org/10.1016/j.foodchem.2020.126549.
  • 32. Kyriakopoulos AM, Dinda B. Cornus mas (Linnaeus) Novel Devised Medicinal Preparations: Bactericidal Effect against Staphylococcus aureus and Pseudomonas aeruginosa. Molecules. 2015;20(6):11202–11218. https://doi.org/10.3390/molecules200611202.
  • 33. Yigit D. Antimicrobial and Antioxidant Evaluation of Fruit Extract from Cornus mas L. Aksaray Univ J Sci Eng. 2018;2(1):41–51. https://doi.org/10.29002/asujse.329856.
  • 34. Asgary S, Rafieian-Kopaei M, Shamsi F, Najafi S, Sahebkar A. Biochemical and histopathological study of the anti-hyperglycemic and anti-hyperlipidemic effects of Cornelian cherry (Cornus mas L.) in alloxan-induced diabetic rats. J Complement Integr Med. 2014;11(2):63–69. https://doi.org/https://doi.org/10.1515/jcim-2013-0022.
  • 35. Soltani R, Gorji A, Asgary S, Sarrafzadegan N, Siavash M. Evaluation of the Effects of Cornus mas L. Fruit Extract on Glycemic Control and Insulin Level in Type 2 Diabetic Adult Patients: A Randomized Double-Blind Placebo-Controlled Clinical Trial. Eddouks M, editör. Evidence-Based Complement Altern Med. 2015;2015:740954. https://doi.org/10.1155/2015/740954.
  • 36. Capcarova M, Kalafova A, Schwarzova M, vd. Cornelian cherry fruit improves glycaemia and manifestations of diabetes in obese Zucker diabetic fatty rats. Res Vet Sci. 2019;126:118–123. https://doi.org/https://doi.org/10.1016/j.rvsc.2019.08.024.
  • 37. Forman V, Haladová M, Grančai D, Ficková M. Antiproliferative Activities of Water Infusions from Leaves of Five Cornus L. Species. Molecules. 2015;20(12):22546–22552. https://doi.org/10.3390/molecules201219786.
  • 38. Yousefi B, Abasi M, Abbasi MM, Jahanban-Esfahlan R. Anti-Proliferative Properties of Cornus mass Fruit in Different Human Cancer Cells. Asian Pac J Cancer Prev. 2015;16(14):5727–5731. https://doi.org/10.7314/apjcp.2015.16.14.5727.
  • 39. Rezaei F, Shokrzadeh M, Majd A, Nezhadsattari T. Cytotoxic effect of hydroalcoholic extract of Cornus Mas L. fruit on MCF7, HepG2 and CHO cell lineby MTT Assay. J Maz Univ Med Sci. 2014;24(113):130–138.
  • 40. Radbeh Z, Asefi N, Hamishehkar H, Roufegarinejad L, Pezeshki A. Novel carriers ensuring enhanced anti-cancer activity of Cornus mas (cornelian cherry) bioactive compounds. Biomed Pharmacother. 2020;125:109906. https://doi.org/https://doi.org/10.1016/j.biopha.2020.109906.
  • 41. Eshaghi M, Zare S, Banihabib N, Nejati V, Farokhi F, Mikaili P. Cardioprotective effect of Cornus mas fruit extract against carbon tetrachloride induced-cardiotoxicity in albino rats. J Basic Appl Sci Res. 2012;2(11):11106–11114.
  • 42. Leskovac A, Joksic G, Jankovic T, Savikin K, Menkovic N. Radioprotective properties of the phytochemically characterized extracts of Crataegus monogyna, Cornus mas and Gentianella austriaca on human lymphocytes in vitro. Planta Med. 2007;73(11):1169–1175. https://doi.org/10.1055/s-2007-981586.
  • 43. Zarei L, Sadrkhanlou R, Shahrooz R, Malekinejad H, Eilkhanizadeh B, Ahmadi A. Protective effects of vitamin E and Cornus mas fruit extract on methotrexate-induced cytotoxicity in sperms of adult mice. Vet Res forum an Int Q J. 2014;5(1):21–27.
  • 44. Francik R, Kryczyk J, Kros̈niak M, Berköz M, Sanocka I, Francik S. The neuroprotective effect of Cornus mas on brain tissue of wistar rats. Sci World J. 2014;2014. https://doi.org/10.1155/2014/847368.
  • 45. Es Haghi M, Dehghan G, Banihabib N, Zare S, Mikaili P, Panahi F. Protective effects of Cornus mas fruit extract on carbon tetrachloride induced nephrotoxicity in rats. Indian J Nephrol. 2014;24(5):291–296. https://doi.org/10.4103/0971-4065.133000. 46. Somi MH, Banihabib N, Dehghan G, Es. Haghi M, Panahi F. Hepatoprotective Effect of Cornus mas Fruits Extract Against Carbon Tetrachloride-Induced Hepatic Damage in Male Albino Rats. Thrita. 2014;3(2):1–5. https://doi.org/10.5812/thrita.17624.
  • 47. Saei H, Hatami H, Azarmi M, Dehghan G. Hepatoprotective effect of cornus mas fruits extract on serum biomarkers in methotrexate-induced liver injury in male rats. 2016;2016:91–98.
  • 48. Darbandi N, Hashemi A, Noori M, Momeni HR. Effect of Cornus mas fruit flavonoids on memory retention, level of plasma glucose and lipids in an intracerebroventricular streptozotocin-induced experimental Alzheimer’s disease model in Wistar rats. Environ Exp Biol. 2016;14(3):113–120. https://doi.org/10.22364/eeb.14.16.
  • 49. Süntar I, Cevik CK, Çeribaşı AO, Gökbulut A. Healing effects of Cornus mas L. in experimentally induced ulcerative colitis in rats: From ethnobotany to pharmacology. J Ethnopharmacol. 2020;248:112322. https://doi.org/10.1016/j.jep.2019.112322.
  • 50. Świerczewska A, Buchholz T, Melzig MF, Czerwińska ME. In vitro α-amylase and pancreatic lipase inhibitory activity of Cornus mas L. and Cornus alba L. fruit extracts. J Food Drug Anal. 2019;27(1):249–258. https://doi.org/10.1016/j.jfda.2018.06.005.

Health Benefits of Cornelian Cherry (Cornus mas L.)

Year 2021, Volume: 7 Issue: 1, 154 - 162, 30.04.2021
https://doi.org/10.19127/mbsjohs.824473

Abstract

Medicinal plants have been used for medical objectives since ancient times due to their beneficial properties, and their uses continue to this day. The Cornelian cherry fruit (Cornus mas L.) is considered to be one of those medicinal plants with important nutritional and therapeutic properties. It has been also used for different medical purposes in many countries in Europe and Asia for centuries due to its various important components in terms of health. Cornelian cherry is known to have antimicrobial, antioxidant, anticancer and anti-inflammatory effects due to its composition of phenolic compounds and ursolic acid. It is reported in the literature that This fruit is used in different countries for different purposes; for the treatment of intestinal and kidney diseases, strengthening immunity, and preventing some types of cancer and others. It is also used in traditional medicine to cure fever, cholera, kidney stones, malaria, urinary tract infections, heat stroke and bleeding. Many studies have reported the positive effect of Cornelian cherry in regulating blood sugar and preventing fat accumulation in the liver. Similar to many countries, it is grown in Turkey in many regions and it is consumed processed or fresh into several crops such as compote, jam, marmalade and fruit leather. This paper has reviewed the investigative studies of the health effect of cornelian cherry.

References

  • 1. Tural S, Koca I. Physico-chemical and antioxidant properties of Cornelian cherry fruits (Cornus mas L.) grown in Turkey. Sci Hortic (Amsterdam). 2008;116(4):362–366. https://doi.org/10.1016/j.scienta.2008.02.003.
  • 2. Benzie IFF. Evolution of dietary antioxidants. Comp Biochem Physiol Part A Mol Integr Physiol. 2003;136(1):113–126. https://doi.org/10.1016/S1095-6433(02)00368-9.
  • 3. Pisoschi AM, Pop A, Iordache F, Stanca L, Predoi G, Serban AI. Oxidative stress mitigation by antioxidants - An overview on their chemistry and influences on health status. Eur J Med Chem. 2021;209:112891. https://doi.org/10.1016/j.ejmech.2020.112891.
  • 4. Seeram NP, Schutzki R, Chandra A, Nair MG. Characterization, Quantification, and Bioactivities of Anthocyanins in Cornus Species. J Agric Food Chem. 2002;50(9):2519–2523. https://doi.org/10.1021/jf0115903.
  • 5. Ercişli S. Cornelian cherry Germplasm Resources of Turkey. J Fruit Ornam Plant Res. 2004;12:87–92.
  • 6. Klimenko S. The Cornelian cherry (Cornus mas L.): collection, preservation, and utilization of genetic resources. J Fruit Ornam Plant Res. 2004;12:93–98. 7. Wyndham R. Cranberry juice and urinary tract infections. Med Today. 2006;7(5):72–73.
  • 8. Badalica-Petrescu M, Dragan S, Ranga F, Fetea F, Socaciu C. Comparative HPLC-DAD-ESI(+)MS Fingerprint and Quantification of Phenolic and Flavonoid Composition of Aqueous Leaf Extracts of Cornus mas and Crataegus monogyna, in Relation to Their Cardiotonic Potential. Not Bot Horti Agrobot Cluj-Napoca. 2014;42(1):9–18. https://doi.org/10.15835/nbha4219270.
  • 9. Drkenda P, Spahić A, Begić-Akagić A, vd. Pomological characteristics of some autochthonous genotypes of Cornelian cherry (Cornus mas L.) in Bosnia and Herzegovina. Erwerbs-obstbau. 2014;56(2):59–66.
  • 10. Milenković-Anđelković AS, Anđelković MZ, Radovanović AN, Radovanović BC, Nikolić V. Phenol composition, DPPH radical scavenging and antimicrobial activity of Cornelian cherry (Cornus mas) fruit and leaf extracts. Hem Ind. 2015;69(4):331–337.
  • 11. Pawlowska AM, Camangi F, Braca A. Quali-quantitative analysis of flavonoids of Cornus mas L.(Cornaceae) fruits. Food Chem. 2010;119(3):1257–1261.
  • 12. Rudrapaul P, Kyriakopoulos AM, De UC, Zoumpourlis V, Dinda B. New flavonoids from the fruits of Cornus mas, Cornaceae. Phytochem Lett. 2015;11:292–295. https://doi.org/10.1016/j.phytol.2015.01.011.
  • 13. Sozański T, Kucharska AZ, Szumny A, vd. The protective effect of the Cornus mas fruits (cornelian cherry) on hypertriglyceridemia and atherosclerosis through PPARα activation in hypercholesterolemic rabbits. Phytomedicine. 2014;21(13):1774–1784. https://doi.org/10.1016/j.phymed.2014.09.005.
  • 14. Behrangi N, Ghafoori H, Farahmand Z, Khani EM, Sanati MH. Comparison among Cornelian cherry and <i>Prunus cerasus</i> According to Phenolic Content and Antioxidant Capacity by Three Various Methods of Extraction. Food Nutr Sci. 2015;06(12):1166–1173. https://doi.org/10.4236/fns.2015.612122.
  • 15. Krivoruchko E V. Carboxylic Acids from Cornus mas. Chem Nat Compd. 2014;50(1):112–113. https://doi.org/10.1007/s10600-014-0879-y.
  • 16. Szumny D, Sozański T, Kucharska AZ, vd. Application of Cornelian cherry iridoid-polyphenolic fraction and loganic acid to reduce intraocular pressure. Evidence-Based Complement Altern Med. 2015;2015. 17. Horváth G, Turcsi E, Molnár P, Szabó LG, Deli J. Isolation and identification of carotenoids in the fruit of Cornelian cherry (Cornus mas L.). Planta Med. 2007;73(09):P_286.
  • 18. Zargari A. Iranian medicinal plants. Tehran Tehran Univ Publ. 1997.
  • 19. PANTELIDIS G, VASILAKAKIS M, MANGANARIS G, DIAMANTIDIS G. Antioxidant capacity, phenol, anthocyanin and ascorbic acid contents in raspberries, blackberries, red currants, gooseberries and Cornelian cherries. Food Chem. 2007;102(3):777–783. https://doi.org/10.1016/j.foodchem.2006.06.021.
  • 20. Popović BM, Štajner D, Slavko K, Sandra B. Antioxidant capacity of Cornelian cherry (Cornus mas L.) – Comparison between permanganate reducing antioxidant capacity and other antioxidant methods. Food Chem. 2012;134(2):734–741. https://doi.org/10.1016/j.foodchem.2012.02.170.
  • 21. Stankovic MS, Zia-Ul-Haq M, Bojovic BM, Topuzovic MD. Total phenolics, flavonoid content and antioxidant power of leaf, flower and fruits from Cornelian cherry (Cornus mas L.). Bulg J Agric Sci. 2014;20(2014):358–363.
  • 22. Demir F, Hakki Kalyoncu İ. Some nutritional, pomological and physical properties of Cornelian cherry (Cornus mas L.). J Food Eng. 2003;60(3):335–341. https://doi.org/https://doi.org/10.1016/S0260-8774(03)00056-6.
  • 23. Dinda B, Kyriakopoulos AM, Dinda S, vd. Cornus mas L. (cornelian cherry), an important European and Asian traditional food and medicine: Ethnomedicine, phytochemistry and pharmacology for its commercial utilization in drug industry. J Ethnopharmacol. 2016;193:670–690. https://doi.org/10.1016/j.jep.2016.09.042.
  • 24. Lewis WH, Elvin-Lewis MPF. Medical botany: plants affecting human health. John Wiley & Sons; 2003.
  • 25. Polatoğlu B, Beşe AV. Sun Drying of Cornelian cherry Fruits (Cornus mas L.). Erzincan Univ J Sci Technol. 2017;10(1):68–77. https://doi.org/10.18185/erzifbed.289008.
  • 26. Zlatković BK, Bogosavljević SS, Radivojević AR, Pavlović MA. Traditional use of the native medicinal plant resource of Mt. Rtanj (Eastern Serbia): Ethnobotanical evaluation and comparison. J Ethnopharmacol. 2014;151(1):704–713.
  • 27. Celik S, Bakırcı I, Şat IG. Physicochemical and organoleptic properties of yogurt with Cornelian cherry paste. Int J Food Prop. 2006;9(3):401–408.
  • 28. Egea T, Signorini MA, Bruschi P, vd. Spirits and liqueurs in European traditional medicine: Their history and ethnobotany in Tuscany and Bologna (Italy). J Ethnopharmacol. 2015;175:241–255.
  • 29. Hsu P-C, Tsai Y-T, Lai J-N, Wu C-T, Lin S-K, Huang C-Y. Integrating traditional Chinese medicine healthcare into diabetes care by reducing the risk of developing kidney failure among type 2 diabetic patients: a population-based case control study. J Ethnopharmacol. 2014;156:358–364.
  • 30. Reich L. Cornelian cherry from the shores of Ancient Greece. Mag Arnold Arbor. 1996;56:2–7.
  • 31. Martinović A, Cavoski I. The exploitation of Cornelian cherry (Cornus mas L.) cultivars and genotypes from Montenegro as a source of natural bioactive compounds. Food Chem. 2020;318:126549. https://doi.org/https://doi.org/10.1016/j.foodchem.2020.126549.
  • 32. Kyriakopoulos AM, Dinda B. Cornus mas (Linnaeus) Novel Devised Medicinal Preparations: Bactericidal Effect against Staphylococcus aureus and Pseudomonas aeruginosa. Molecules. 2015;20(6):11202–11218. https://doi.org/10.3390/molecules200611202.
  • 33. Yigit D. Antimicrobial and Antioxidant Evaluation of Fruit Extract from Cornus mas L. Aksaray Univ J Sci Eng. 2018;2(1):41–51. https://doi.org/10.29002/asujse.329856.
  • 34. Asgary S, Rafieian-Kopaei M, Shamsi F, Najafi S, Sahebkar A. Biochemical and histopathological study of the anti-hyperglycemic and anti-hyperlipidemic effects of Cornelian cherry (Cornus mas L.) in alloxan-induced diabetic rats. J Complement Integr Med. 2014;11(2):63–69. https://doi.org/https://doi.org/10.1515/jcim-2013-0022.
  • 35. Soltani R, Gorji A, Asgary S, Sarrafzadegan N, Siavash M. Evaluation of the Effects of Cornus mas L. Fruit Extract on Glycemic Control and Insulin Level in Type 2 Diabetic Adult Patients: A Randomized Double-Blind Placebo-Controlled Clinical Trial. Eddouks M, editör. Evidence-Based Complement Altern Med. 2015;2015:740954. https://doi.org/10.1155/2015/740954.
  • 36. Capcarova M, Kalafova A, Schwarzova M, vd. Cornelian cherry fruit improves glycaemia and manifestations of diabetes in obese Zucker diabetic fatty rats. Res Vet Sci. 2019;126:118–123. https://doi.org/https://doi.org/10.1016/j.rvsc.2019.08.024.
  • 37. Forman V, Haladová M, Grančai D, Ficková M. Antiproliferative Activities of Water Infusions from Leaves of Five Cornus L. Species. Molecules. 2015;20(12):22546–22552. https://doi.org/10.3390/molecules201219786.
  • 38. Yousefi B, Abasi M, Abbasi MM, Jahanban-Esfahlan R. Anti-Proliferative Properties of Cornus mass Fruit in Different Human Cancer Cells. Asian Pac J Cancer Prev. 2015;16(14):5727–5731. https://doi.org/10.7314/apjcp.2015.16.14.5727.
  • 39. Rezaei F, Shokrzadeh M, Majd A, Nezhadsattari T. Cytotoxic effect of hydroalcoholic extract of Cornus Mas L. fruit on MCF7, HepG2 and CHO cell lineby MTT Assay. J Maz Univ Med Sci. 2014;24(113):130–138.
  • 40. Radbeh Z, Asefi N, Hamishehkar H, Roufegarinejad L, Pezeshki A. Novel carriers ensuring enhanced anti-cancer activity of Cornus mas (cornelian cherry) bioactive compounds. Biomed Pharmacother. 2020;125:109906. https://doi.org/https://doi.org/10.1016/j.biopha.2020.109906.
  • 41. Eshaghi M, Zare S, Banihabib N, Nejati V, Farokhi F, Mikaili P. Cardioprotective effect of Cornus mas fruit extract against carbon tetrachloride induced-cardiotoxicity in albino rats. J Basic Appl Sci Res. 2012;2(11):11106–11114.
  • 42. Leskovac A, Joksic G, Jankovic T, Savikin K, Menkovic N. Radioprotective properties of the phytochemically characterized extracts of Crataegus monogyna, Cornus mas and Gentianella austriaca on human lymphocytes in vitro. Planta Med. 2007;73(11):1169–1175. https://doi.org/10.1055/s-2007-981586.
  • 43. Zarei L, Sadrkhanlou R, Shahrooz R, Malekinejad H, Eilkhanizadeh B, Ahmadi A. Protective effects of vitamin E and Cornus mas fruit extract on methotrexate-induced cytotoxicity in sperms of adult mice. Vet Res forum an Int Q J. 2014;5(1):21–27.
  • 44. Francik R, Kryczyk J, Kros̈niak M, Berköz M, Sanocka I, Francik S. The neuroprotective effect of Cornus mas on brain tissue of wistar rats. Sci World J. 2014;2014. https://doi.org/10.1155/2014/847368.
  • 45. Es Haghi M, Dehghan G, Banihabib N, Zare S, Mikaili P, Panahi F. Protective effects of Cornus mas fruit extract on carbon tetrachloride induced nephrotoxicity in rats. Indian J Nephrol. 2014;24(5):291–296. https://doi.org/10.4103/0971-4065.133000. 46. Somi MH, Banihabib N, Dehghan G, Es. Haghi M, Panahi F. Hepatoprotective Effect of Cornus mas Fruits Extract Against Carbon Tetrachloride-Induced Hepatic Damage in Male Albino Rats. Thrita. 2014;3(2):1–5. https://doi.org/10.5812/thrita.17624.
  • 47. Saei H, Hatami H, Azarmi M, Dehghan G. Hepatoprotective effect of cornus mas fruits extract on serum biomarkers in methotrexate-induced liver injury in male rats. 2016;2016:91–98.
  • 48. Darbandi N, Hashemi A, Noori M, Momeni HR. Effect of Cornus mas fruit flavonoids on memory retention, level of plasma glucose and lipids in an intracerebroventricular streptozotocin-induced experimental Alzheimer’s disease model in Wistar rats. Environ Exp Biol. 2016;14(3):113–120. https://doi.org/10.22364/eeb.14.16.
  • 49. Süntar I, Cevik CK, Çeribaşı AO, Gökbulut A. Healing effects of Cornus mas L. in experimentally induced ulcerative colitis in rats: From ethnobotany to pharmacology. J Ethnopharmacol. 2020;248:112322. https://doi.org/10.1016/j.jep.2019.112322.
  • 50. Świerczewska A, Buchholz T, Melzig MF, Czerwińska ME. In vitro α-amylase and pancreatic lipase inhibitory activity of Cornus mas L. and Cornus alba L. fruit extracts. J Food Drug Anal. 2019;27(1):249–258. https://doi.org/10.1016/j.jfda.2018.06.005.
There are 47 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Review
Authors

Zeliha Kaya 0000-0002-3285-9659

İlkay Koca 0000-0001-6089-8586

Publication Date April 30, 2021
Published in Issue Year 2021 Volume: 7 Issue: 1

Cite

Vancouver Kaya Z, Koca İ. Health Benefits of Cornelian Cherry (Cornus mas L.). Mid Blac Sea J Health Sci. 2021;7(1):154-62.

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