Predictive Role of Large Unstained Cells (LUC) and Hematological Data in the Differential Diagnosis of Orchitis and Testicular Torsion

Year 2021, Volume: 7 Issue: 1, 97 - 103, 30.04.2021

Buğra Bilge Keseroğlu , Bülent Güngörer

https://doi.org/10.19127/mbsjohs.882264

Abstract

Objective: The main aim of this retrospective evaluation of patients presenting with the complaint of acute scrotal pain was to investigate whether large unstained cells (LUC) in the hematological data, percentage of LUC, and the other haematological parameters would be of benefit in differential diagnosis. The secondary aim was to investigate the utility of LUC and LUC% as a new biochemical marker in the differential diagnosis of TT and EO.
Methods: In this study, a retrospective evaluation was made of patients who presented with the complaint of acute scrotal pain at the emergency polyclinic. The patients were evaluated in three groups; testicular torsion, orchitis, and the control group. Primarily the large unstained cell and other hematological data of the patients were evaluated.
Results: Statistical differences were evaluated in LUC, LUC%, platelet, neutrophil, leucocyte, mean platelet volume, neutrophil / lymphocyte, platelet / lymphocyte values among the groups (p values respectively 0.001, ˂0.001, 0.491, ˂0.001, ˂0.001, 0.031, ˂0.001, 0.001). The cutoff values for the differentiation of epididimo-orchitis (EO) were determined in the differential diagnosis of EO and TT. The highest area under curve values were found for LUC, LUC% and neutrophils, respectively, 0.752 (0.660-0.843), 0.698 (0.605-0.790), 0.383 (0.284-0.482).
Conclusion: The results of this study showed that the LUC and LUC% values obtained from complete blood count (CBC) can be reliably used in the differential diagnosis of EO and TT

Keywords

orchitis, large unstained cell(LUC), testicular torsion, predictive role, nlr

Supporting Institution

YOK

Project Number

Etik Kurul No:E1-20*1126

Thanks

*

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