Kombine Acellular Kollajen Matrisi ve Yüksek Tibial Osteotomi Tedavisi Osteokondral Kusurlarda Etkili Midir? Ön çalışma

Year 2017, , 2 - 6, 23.04.2017

Mehmet Nuri Konya , Erdal Horata , Gökhan Maralcan , Abdullah Recep Erten , Ozan Turamanlar

https://doi.org/10.30565/medalanya.270371

Cited By: 1

Abstract

Amaç: Bu çalışmada,
aselüler kollajen matriks (AKM) ve Yüksek Tibial osteotomi-hücresel kollajen
matriks (AKM-YTO) kombinasyonu ile tedavi edilen 12 hastanın klinik ve
radyolojik sonuçlarını karşılaştırmak istedik.

 Yöntem: Bu çalışmada,
2014-2016 yılları arasında etik onayları alındıktan sonra kondral lezyonu olan
12 hasta prospektif olarak değerlendirildi. Manyetik rezonans görüntüleme(MRG)
ile kıkırdak hasarı tespit edildi ve kıkırdak dejenerasyonun hacmi Mimics
medikal görüntü işleme yazılım sistemi ile hesaplandı ve eksen sapması ise
X-ray ile teşhis edildi. Hastalar sadece AKM(Grup 1) ve kombine AKM-YTO(Grup 2)
olmak üzere iki gruba ayrıldı.

 Bulgular: Sadece AKM grubu 5
hastadan oluşmaktadır. Bu grupta ameliyat öncesi ortalama kıkırdak lezyon hacmi
77.11 ± 137.5 (0.27- 321.61) idi. Operasyon sonrası ortalama diz(HSS) skoru
175.20 ± 24.4 (150-203) ve kıkırdak lezyon hacmi 0.3 ± 0.03 (0-0.8) idi.
AKM-YTO grubu 7 hastadan oluşmaktadır. Bu grupta ise ameliyat öncesi ortalama
kıkırdak lezyon hacmi 112.72 ± 239 (0.27-653) idi. Ameliyat sonrası ortalama
diz(HSS) skoru 155 ± 20.4 (135-183) ve kıkırdak lezyon hacmi 0.26 ± 0.09
(0-0.69) idi.

 Sonuç: Bu sonuçlara göre,
tüm hastaların HSS skorları ve kıkırdak hacmi artmıştır ancak iki grup arasında
anlamlı bir farklılık bulunmamaktadır.

Keywords

Kıkırdak, Yüksek Tibial Osteotomi, Asellüler Kollajen Matris

İs Combined Acellular Collagen Matrix and High Tibial Osteotomy Treatment Effective In Osteochondral Defects? Preliminary Study

Abstract

Aim:  In this study, we want to compare clinical and
radiological results of 12 patient treated with acellular collagen matrix (ACM)
and High Tibial osteotomy-cellular collagen matrix(ACM-HTO) combination.

Method: In this study, we
evaluated 12 patients with chondral lesion prospectively the years of between
2014- 2016 after ethical approval. Cartilage damage was diagnosed with MRI and
cartilage degeneration volume was calculated with Mimics medical image
processing software and axis deviation was diagnosed with ortho X-ray. Patients
were divided into two groups. ACM only (Group 1) and ACM- HTO (Group 2).

 

Results:
 ACM only group consists of 5 patients.
Preoperative mean of chondral lesion volume was 77.11±137.5 (0.27-321.61).
Post-operative mean Knee  score was
175.20±24.4(150-203) and chondral lesion volume was 0.3±0.03(0-0.8). ACM-HTO
group consists of 7 patients. Preoperative mean of chondral lesion volume was
112.72±239(0.27- 653). Post-operative mean of HSS score was 155±20.4(135-183)
and chondral lesion volume was 0.26±0.09(0-0.69).

Conclusion: According to these
results, all patients’ HSS scores and Cartilage volume are increased, but there
were no significant differences were found between two groups.

Keywords

Keywords: cartilage, high tibial osteotomy, acellular collagen matrix

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