Evaluation of Prognostic Factors In Nasopharyngeal Cancers

Year 2017, , 72 - 76, 15.07.2017

Rüstem Hasanov Hüseyin Günizi , Kenan Güney

https://doi.org/10.30565/medalanya.314531

Abstract

Aim: We aimed to examine
prognostic factors that affect the survival of patients with nasopharyngeal
cancer (NPC) who were diagnosed and treated in our clinic.

Methods: Patients with
nasopharyngeal cancer, who were diagnosed and treated in our clinic between 2009-2013,
were examined retrospectively.

Results: In our study, 33
patients were male (%73.3), 12 patients were female (%26.6), and  male/female ratio was 2.75. Mean age was
50,8; the youngest patient was 14 and the oldest one was 84 years old.  The most common presenting cause was cervical
lymph node metastasis (%66,7). %66,6 of our patients had advanced stage tumor
(Stage 3-4). Longer survival was detected in low T-stage patients, whereas no
relation was determined between N-stage and survival. No statistical relation
was determined between histopathological types and 2-year survival. Longer
survival was observed in young age group and male patients; however, this was
not statistically significant.

Conclusion: Younger age are good
prognostic factors, however, the advanced T and N stages at diagnosis are poor
prognostic factors. Therefore, early diagnosis is important in terms of
treatment and survival.

Keywords

Nasopharynx, Prognostic factors, Retrospective

Nazofaringeal Kanserlerde Prognostik Faktörlerin Değerlendirilmesi

Abstract

 Amaç: Kliniğimizde teşhis
ve tedavi edilen nazofaringeal kanserli (NPC) hastaların hayatta kalmasını
etkileyen prognostik faktörleri incelemektir.

Yöntemler: Kliniğimizde
2009-2013 yılları arasında teşhis ve tedavi edilen nazofaringeal kanserli
hastalar geriye dönük olarak incelendi.

Bulgular: Çalışmamızda 33
hasta erkek (% 73.3), 12 hasta kadın (% 26.6), erkek / kadın oranı 2.75 idi.
Ortalama yaş 50,8; En genç hasta 14 ve en yaşlısı 84 yaşında idi. En sık
görülen neden servikal lenf nodu metastazı (% 66,7) idi. Hastalarımızın%
66,6'sında ileri evre tümör vardı (Evre 3-4). Düşük T evresi hastalarında daha
uzun sağkalım süresi saptanırken, N-evresi ile sağkalım arasında ilişki
saptanmadı. Histopatolojik tiplerle 2 yıllık sağkalım arasında istatistiksel
olarak bir ilişki saptanmadı. Genç yaş grubu ve erkek hastalarda daha uzun
sağkalım süresi gözlemlendi fakat bu istatistiksel olarak anlamlı değildi.

Sonuç: Genç yaş iyi
prognostik faktörlerdir, ancak tanıdaki ilerlemiş T ve N evreleri kötü
prognostik faktörlerdir. Bu nedenle erken teşhis, tedavi ve sağkalım açısından
önemlidir.

Keywords

nazofarenks, prognostik faktörler, retrospektif

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