The Impact of Prolotherapy and Steroid Injection on De Quervain's Tenosynovitis: A Retrospective Outcome Study

Year 2024, Volume: 8 Issue: 1, 68 - 76, 30.04.2024

Hakan Zora , Gökhan Bayrak

https://doi.org/10.30565/medalanya.1456072

Cited By: 1

Abstract

Aim: Patients with De Quervain's stenosing tenosynovitis (DQT) experience problems in daily living activities due to the chronic inflammatory process and tenderness around the wrist. This study aimed to compare the effects of prolotherapy and steroid injection on short-term functional outcomes in DQT patients.

Methods: In this retrospective study between January 2022 and 2023, a cohort of 34 patients with complete demographic data and elbow pain and functional scores, which were recorded at pre-treatment, two weeks, and six weeks post-treatment, was divided into the steroid injection (n=17) and prolotherapy (n=17) groups. Demographic and clinical data of all patients were recorded. The outcomes of the Visual Analogue Scale (VAS) score for wrist pain, Quick Disability Assessment of Arm, Shoulder, and Hand Problems (QuickDASH), and the Health Assessment Questionnaire (HAQ) for wrist functions were examined.

Results: Initial assessments did not reveal any differences between groups in terms of VAS (p=0.756), QuickDASH (p=0.168), and HAQ (p=0.615). In the second week post-treatment, there was a significant reduction in VAS, QuickDASH, and HAQ in steroid injection compared to the prolotherapy (p=0.001). This difference continued at sixth-week post-treatment; VAS (p=0.007), QuickDASH (p=0.003), and HAQ (p=0.011) were found to be significantly lower in steroid injection than in the prolotherapy.

Conclusion:Our findings underscore the superior effectiveness of steroid injection compared to prolotherapy in reducing wrist pain and improving functional outcomes in patients with DQT. These findings benefit orthopedic settings in choosing treatment options logically, though further research is needed to understand long-term effects and mechanisms.

Keywords

De Quervain stenosing tenosynovitis, injections, steroids, prolotherapy

Ethical Statement

Muş Alparslan University Scientific Research and Publication Ethics Committee approved the study (Date: 07.03.2024, Number:134645-5/53).

Supporting Institution

None.

Thanks

None.

Proloterapi ve Steroid Enjeksiyonunun De Quervain Tenosinoviti Üzerindeki Etkisi: Retrospektif Sonuç Araştırması

Abstract

Amaç: De Quervain stenozan tenosinovitli (DQT) hastalar, kronik inflamatuar süreç ve el bileği çevresindeki hassasiyet nedeniyle günlük yaşam aktivitelerinde problemler yaşamaktadır. Bu çalışmanın amacı DQT hastalarında proloterapi ve steroid enjeksiyonunun kısa dönem fonksiyonel sonuçlar üzerindeki etkilerini karşılaştırmaktır.

Yöntem: Ocak 2022-2023 tarihleri arasında yapılan bu retrospektif çalışmada demografik verileri eksiksiz olan ve tedavi öncesi, tedavi sonrası iki hafta ve altı hafta dirsek ağrısı ve fonksiyonel skorları kaydedilen 34 hastadan oluşan bir kohort steroid enjeksiyonu (n=17) ve proloterapi (n=17) gruplarına ayrıldı. Tüm hastaların demografik ve klinik verileri kaydedildi. El bileği ağrısı için Görsel Analog Skalası (GAS) skoru, el bileği fonksiyonları için Kol, Omuz ve El Problemlerinin Hızlı Engellilik Değerlendirmesi (QuickDASH) ve Sağlık Değerlendirme Anketi (SDA) sonuçları incelendi.

Bulgular: İlk değerlendirmelerde GAS (p=0,756), QuickDASH (p=0,168) ve SDA (p=0,615) açısından gruplar arasında fark yoktu. Tedavi sonrası ikinci haftada, steroid enjeksiyonunda proloterapiye kıyasla GAS, QuickDASH ve SDA'da anlamlı bir azalma görüldü (p=0,001). Bu fark tedavi sonrası altıncı haftada da devam etti; GAS (p=0,007), QuickDASH (p=0,003) ve SDA (p=0,011) steroid enjeksiyonunda proloterapiye göre anlamlı şekilde düşük bulundu.

Sonuç: Elde edilen bulgular DQT'li hastalarda steroid enjeksiyonunun proloterapiye kıyasla el bileği ağrısını azaltmada ve fonksiyonel sonuçları iyileştirmedeki üstün etkinliğinin altını çizmektedir. Bu bulgular, tedavi seçeneklerinin mantıklı bir şekilde seçilmesinde ortopedik çerçeveye fayda sağlamaktadır, ancak uzun vadeli etkileri ve mekanizmaları anlamak için daha fazla araştırmaya ihtiyaç vardır.

Keywords

De Quervain stenozan tenosinoviti, enjeksiyonlar, steroidler, proloterapi

Ethical Statement

Muş Alparslan Üniversitesi Bilimsel Araştırma ve Yayın Etiği Kurulu çalışmayı onaylamıştır (Tarih: 07.03.2024, Sayı:134645-5/53).

Supporting Institution

Yoktur.

Thanks

Yoktur.

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