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Year 2015, Volume: 2 Issue: 1, 1 - 11, 27.11.2015

Abstract

References

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  • Joint National Committee on Prevention, Evaluation and Treatment of High Blood Pressure. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure (JNC 7 Report). National Institutes of Health; National Heart, Lung and Blood Institute. JAMA 2003; 289: 2560-2572
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B 12 VİTAMİN DÜZEYİ EKSİKLİĞİ OLAN HASTALARLA NORMAL OLAN HASTALARIN KARDİYOVASKÜLER RİSK FAKTÖRLERİ AÇISINDAN RETROSPEKTİF OLARAK DEĞERLENDİRMESİ

Year 2015, Volume: 2 Issue: 1, 1 - 11, 27.11.2015

Abstract

Kardiyovasküler hastalık açısından bilinen risk faktörleri olan obezite, ileri yaş, hipertansiyon,
dislipidemi, diyabet, sigara gibi faktörlerin yanı sıra yapılan çalışmalar B 12 vitamin eksikliğininde
homosistein düzeyini artırarak koroner hastalıklar için bağımsız bir risk faktörü oluşturduğu
gösterilmiştir. Bu çalışmada polikliniğimize başvurmuş ve B 12 vitamin eksikliği görülmüş hastaları, B 12
düzeyi normal olan hastalara göre diğer kardiyovasküler risk faktörleri açısından değerlendirdik ve bu
hastalarda olası koroner hastalıklar için var olan risk faktörlerini göstermeye çalıştık. Bülent Ecevit
Üniversitesi Uygulama ve Araştırma Hastanesi Aile Hekimliği Polikliniği’ne son 1 (bir) yıl içinde
başvurmuş ve B 12 vitamin eksikliği gözlemlenmiş hastaların dosyalarından sağlık bilgileri, ilaç kullanım
öyküleri, sigara, kronik hastalık, aile öykülerini kullanarak, fizik muayene bulgularından kan basıncı ve
VKI’lerıne bakarak, istenilen laboratuvar sonuçlarından B 12 düzeyi, HDL, LDL, total kolesterol, CRP,
trigliserid düzeylerine bakarak var olan kardiyovasküler riskleri belirlemeyi amaçladık. Var olan risk
faktörleri bakımından her iki cinsiyet ve B 12 vitamin eksikliği olan ve olmayan hastalar ayrı ayrı
değerlendirilmiş ve framingham risk skorlaması ile gelecek on yılda ki olası riskleri hesaplanmıştır.
Hastaların framingham skorlamasına göre beklenen on yıllık risk faktörleri açısından aralarında anlamlı
bir fark bulunmamıştır.

References

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  • Kıvanç M.M, Bozkurt G, Bayram S, Özer Y, Kardiyak yoğun bakim ünitelerinde rehabilitasyon uygulamalarının incelenmesi. İçinde: Onat A. (ed.) Türk Kardiyoloji Derneği Arşivi XVI. Ulusal Kardiyoloji Kongresi Bildiri Özetleri. İstanbul: 2000: SB 149.
  • Ulusal Kalp Sağlığı Politikası, Türk Kardiyoloji Derneği web sayfası http://www.tkd.org.tr/pages.asp.pg=276
  • Minnet C. Çocukluk Çağında B 12 Vitamini Eksikliğinin Oksidan-Antioksidan Sistem ve DNA Hasarı İle İlişkisi (tez). Şanlıurfa: Harran Üniversitesi Tıp Fakültesi; 2006.
  • Türkiye kalp ve damar hastalıklarını önleme ve kontrol etme programı 2008
  • Yesilbursa D., Serdar O.A., Gemici K.,Kaya K.,Güllüsü S.,Aydınlar A. Ve ark. Koroner arter hastalığında risk faktörlerinin ve anjiografik bulguların cinsiyetlere göre karsılaştırılması. Türkiye Tıp Dergisi.1998;5(1):17-20.
  • Coldiz G.A., Willet V.C., Stamgfer M.J. Menopause and the risk of coronary heart disease in women. N. Engl J. Med. 1987; 316: 1105-1111.
  • Djanmohammedi R.A., Sansoy V., Yigit Z., Gürmen T.,Gülbaran M., Öztürk S. Ve ark. Koroner arter hastalarında sekonder korumanın etkinliğinin değerlendirilmesi. Türk Kardiyoloji Derneği Arşivi. 2000; 28 (4): 216-223.
  • Onat A, Büyük öztürk K, Sansoy V, Surdum Avci G, Çam N, Akgün G, Tokgözoglu L, Çağlar N, San M, Nişancı Y, Oto A, Ergene O,Türk Kardiyoloji Derneği, Koroner Kalp hastalığı, Korunma ve Tedavi Kılavuzu, İstanbul. Yenilik Basımevi, 2002
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  • Türk Kardiyoloji Derneği Ulusal Hipertansiyon Tedavi ve Takip Kılavuzu. Türk Kardiyoloji Derneği Arş. 2000;28: 335-97
  • Karpuz H, Gizli Düşman Artik daha mı tehlikeli. Sanovizon, 4: 10-14, 2004
  • Expert panel on detection, evaluation and treatment high blood cholesterol in adults. Executive summary of the third report of the national cholesterol education program (NCEP). (adult tratment panel III). JAMA 2001; 285:2486
  • Diabetes Mellitus Ve Komplikasyonlarının Tanı, Tedavi Ve İzlem Kılavuzu-2011
  • The Diabetes Control and Complications Trial Research Group.The efect of intensive treatement of diabetes on the developement and progression of long term complications in insulin dependent diabetes mellitus. N Engl J Med 1993;329: 997-86
  • Wilhemsson C, Elmfeldt D et al:Smoking and myocardial infarction. Lancet 1975;1:415-
  • US Department of Health and Human Services. The Health Consequences of Smoking: Cardiovascular Disease_ A Report of the Surgeon General. Washington, DC: Office of Smoking and Health, US Gover nment Printing Office; 1983.
  • Eckel RH, Krauss RM. American Heart Association call to action: Obesity as a majör risk factors. Circulation 1998; 97: 2099
  • National Task Force on the Prevention and Treatment of Obesity. Dieting and the development of eating disorders in overweight and obese adults. Arch Int Med 2000;
  • : 2581-9.
  • Calle EE, Thun MJ, Petrilli JM, et al. Body- mass index and mortality in a prospective cohort of U.S. adults. N Eng J Med 1999; 341: 1097
  • Onat A, Şenocak M. Obesity in Turkish adults: prevalence, validity as a coronary risk factors and interrelation with other risk factors. Int J Ang 1995; 4: 94-8.
  • Joint National Committee on Prevention, Evaluation and Treatment of High Blood Pressure. The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation and Treatment of High Blood Pressure (JNC 7 Report). National Institutes of Health; National Heart, Lung and Blood Institute. JAMA 2003; 289: 2560-2572
  • Van den Hoogen PCW, Feskens EJM, Jaglekerke NJD. The relation betveen blood pressure and mortality due to coronary heart disease among men in different parts of the Word. N Eng J Med 2000; 342: 1
  • Hurt’s The Heart. Valentin Fuster, R. Wayne Alexander, Robert O’Rourke. 10. Baskısının Türkçe çevirisi. And Danışmanlık Eğitim Yayıncılık ve Organizasyon Ltd. Şti. 1. Basım. 2002 Sayfa, 1065-1109
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  • Jousilahti P, Tuomilehto J, Vartiainene E, et al. Body weight, cardiovascular risk factors, and coronary mortality. Circulation 1996; 93: 1372-9
  • Prof. Dr. Altan Onat, Prof. Dr. Vedat Sansoy, Prof. Dr. İnan Soydan, Prof. Dr. Lale Tokgözoğlu, Prof. Dr. Kamil Adalet., TEKHARF; On iki Yıllık İzleme Deneyimine Göre Türk Erişkinlerinde Kalp Sağlığı. Argos İletişim Hizmetleri Reklamcılık ve Ticaret Anonim Şirketi. Temmuz 2003, İstanbul.
  • Fuster V, Alexander RW, O’Rourke RA: Hurst’sThe Heart1.baski ;3:1131-1160,2002
  • Basic Pathology, Kumar, Cotran, Robbins Türkçesi, Nobel Tıp Kitabevleri Ltd. Şti. Temmuz 2000. Sayfa 283-289
  • İç Hastalıkları. İliçin, Biberoğlu, Süleymanlar, Ünal. Güneş Kitabevi 2. baskı, 2003. Sayfa, 449-474
  • Hopkins PN, Williams RR. Human genetics and coronary heart disease: A public heart perspective. Annu Rev Nutr 1989; 9:303
  • Hurt’s The Heart. Valentin Fuster, R. Wayne Alexander, Robert O’Rourke. 10. Baskısının Türkçe çevirisi. And Danışmanlık Eğitim Yayıncılık ve Organizasyon Ltd. Şti. 1. Basım. 2002 Sayfa, 1065-1109
  • Fletcher GF, Balady G, Blair SN, et al. Statement on exercise: Benefits and recommendations for physical activity. Circulation 1996; 94:857
  • Haskell WL. Sedentary lifestyle as a risk factors for coronary heart disease. In: Pearson TA, ed. Primer in Preventive Cardiology. Dallas: American Heart Association; 1994:173
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There are 93 citations in total.

Details

Primary Language TR, EN
Journal Section Makaleler
Authors

HAMDİ Küçük This is me

GÜNTER Dilsiz This is me

NEJAT Demircan

EROL Aktunç This is me

Ayşe Demir Akça

Fürüzan Köktürk

Publication Date November 27, 2015
Published in Issue Year 2015 Volume: 2 Issue: 1

Cite

APA Küçük, H., Dilsiz, G., Demircan, N., Aktunç, E., et al. (2015). B 12 VİTAMİN DÜZEYİ EKSİKLİĞİ OLAN HASTALARLA NORMAL OLAN HASTALARIN KARDİYOVASKÜLER RİSK FAKTÖRLERİ AÇISINDAN RETROSPEKTİF OLARAK DEĞERLENDİRMESİ. Zonguldak Karaelmas Üniversitesi Tıp Fakültesi Dergisi Medi ForuM, 2(1), 1-11.
AMA Küçük H, Dilsiz G, Demircan N, Aktunç E, Demir Akça A, Köktürk F. B 12 VİTAMİN DÜZEYİ EKSİKLİĞİ OLAN HASTALARLA NORMAL OLAN HASTALARIN KARDİYOVASKÜLER RİSK FAKTÖRLERİ AÇISINDAN RETROSPEKTİF OLARAK DEĞERLENDİRMESİ. Zonguldak Karaelmas Üniversitesi Tıp Fakültesi Dergisi Medi ForuM. November 2015;2(1):1-11.
Chicago Küçük, HAMDİ, GÜNTER Dilsiz, NEJAT Demircan, EROL Aktunç, Ayşe Demir Akça, and Fürüzan Köktürk. “B 12 VİTAMİN DÜZEYİ EKSİKLİĞİ OLAN HASTALARLA NORMAL OLAN HASTALARIN KARDİYOVASKÜLER RİSK FAKTÖRLERİ AÇISINDAN RETROSPEKTİF OLARAK DEĞERLENDİRMESİ”. Zonguldak Karaelmas Üniversitesi Tıp Fakültesi Dergisi Medi ForuM 2, no. 1 (November 2015): 1-11.
EndNote Küçük H, Dilsiz G, Demircan N, Aktunç E, Demir Akça A, Köktürk F (November 1, 2015) B 12 VİTAMİN DÜZEYİ EKSİKLİĞİ OLAN HASTALARLA NORMAL OLAN HASTALARIN KARDİYOVASKÜLER RİSK FAKTÖRLERİ AÇISINDAN RETROSPEKTİF OLARAK DEĞERLENDİRMESİ. Zonguldak Karaelmas Üniversitesi Tıp Fakültesi Dergisi Medi ForuM 2 1 1–11.
IEEE H. Küçük, G. Dilsiz, N. Demircan, E. Aktunç, A. Demir Akça, and F. Köktürk, “B 12 VİTAMİN DÜZEYİ EKSİKLİĞİ OLAN HASTALARLA NORMAL OLAN HASTALARIN KARDİYOVASKÜLER RİSK FAKTÖRLERİ AÇISINDAN RETROSPEKTİF OLARAK DEĞERLENDİRMESİ”, Zonguldak Karaelmas Üniversitesi Tıp Fakültesi Dergisi Medi ForuM, vol. 2, no. 1, pp. 1–11, 2015.
ISNAD Küçük, HAMDİ et al. “B 12 VİTAMİN DÜZEYİ EKSİKLİĞİ OLAN HASTALARLA NORMAL OLAN HASTALARIN KARDİYOVASKÜLER RİSK FAKTÖRLERİ AÇISINDAN RETROSPEKTİF OLARAK DEĞERLENDİRMESİ”. Zonguldak Karaelmas Üniversitesi Tıp Fakültesi Dergisi Medi ForuM 2/1 (November 2015), 1-11.
JAMA Küçük H, Dilsiz G, Demircan N, Aktunç E, Demir Akça A, Köktürk F. B 12 VİTAMİN DÜZEYİ EKSİKLİĞİ OLAN HASTALARLA NORMAL OLAN HASTALARIN KARDİYOVASKÜLER RİSK FAKTÖRLERİ AÇISINDAN RETROSPEKTİF OLARAK DEĞERLENDİRMESİ. Zonguldak Karaelmas Üniversitesi Tıp Fakültesi Dergisi Medi ForuM. 2015;2:1–11.
MLA Küçük, HAMDİ et al. “B 12 VİTAMİN DÜZEYİ EKSİKLİĞİ OLAN HASTALARLA NORMAL OLAN HASTALARIN KARDİYOVASKÜLER RİSK FAKTÖRLERİ AÇISINDAN RETROSPEKTİF OLARAK DEĞERLENDİRMESİ”. Zonguldak Karaelmas Üniversitesi Tıp Fakültesi Dergisi Medi ForuM, vol. 2, no. 1, 2015, pp. 1-11.
Vancouver Küçük H, Dilsiz G, Demircan N, Aktunç E, Demir Akça A, Köktürk F. B 12 VİTAMİN DÜZEYİ EKSİKLİĞİ OLAN HASTALARLA NORMAL OLAN HASTALARIN KARDİYOVASKÜLER RİSK FAKTÖRLERİ AÇISINDAN RETROSPEKTİF OLARAK DEĞERLENDİRMESİ. Zonguldak Karaelmas Üniversitesi Tıp Fakültesi Dergisi Medi ForuM. 2015;2(1):1-11.