The Relationship between Helicobacter Pylori and Intestinal Parasites in Patients with Peptic Ulcer

Year 2023, Volume: 5 Issue: 1, 132 - 9, 15.01.2023

Yasemin Kaya , Ülkü Karaman , Cemil Çolak , Hamza Çınar , Ahmet Karataş , Neval Berrin Arserim , Gamze Yolalan , Şermin Top

https://doi.org/10.37990/medr.1183913

Cited By: 1

Abstract

Aim: This study aimed to evaluate the frequency of Helicobacter pylori (H. pylori), risk factors, and co-infection with intestinal parasites in adult patients presenting gastrointestinal complaints.
Materials and Methods: The working group of the study consisted of 385 patients with gastrointestinal complaints. A questionnaire including questions aiming to canvass the socio-demographic features, lifestyles, and complaints of the patients was administered to the study population. Cellophane slide method, native-lugol, sedimentation and Modified kinyoun acid-fast methods were used for the diagnosis of parasites in stool, under microscope. The H. pylori antigen was studied in the stool sample taken for the diagnosis of H. pylori.
Results: H. pylori positivity was found to be 27.79% in the patients included in the study. 76.6% of those who are positive for H. pylori are women, and the positivity rate was found to be higher at the age of 40 and over (75.7%). The majority of patients with H. pylori positivity expressed being married (73.8%), having middle / low-income (89.7%), having a low educational background (82.2%), living in a village (55.1%), and in a nuclear family (72.2%) (p<0.001). H. pylori positivity was higher in those who used tap water (40.2%) and those who had a vegetable-based diet (75.7%) (p<0.001). The study found a statistically significant correlation between Entamoeba histoloytica and Enterobius vermicularis positivity and H. pylori positivity (p<0.05 p<0.001, respectively). The calculated odds ratio showed that H. pylori positivity was 1.19 times higher in Entamoeba histoloytica positivity and 11.27 times higher in Enterobius vermicularis positivity.
Conclusion: Larger and more comprehensive studies should be performed to understand better the epidemiology, clinical effects, treatment, and control of H. pylori co-infection. 

Keywords

Peptic Ulcer, Helicobacter pylori, Intestinal Parasites

Supporting Institution

This research was financially supported by the Scientific Project Office of Ordu University (AR-1663).

Project Number

AR-1663

Thanks

We would like to thank Ordu University Scientific Research Projects Coordination Unit for its support for the AR-1663 project.

Peptik Ülser Hastalarında Helicobacter pylori ile Barsak Parazitleri Arasındaki İlişki

Abstract

Amaç: Bu çalışmanın amacı, gastrointestinal şikayetlerle başvuran erişkin hastalarda H. pylori sıklığı, risk faktörleri ve intestinal parazitlerle ko-enfeksiyonunu değerlendirmektir.
Materyal ve Metod: Gastrointestinal şikayetleri olan 385 hasta çalışmaya alınmıştır. Hastaların sosyo-demografik özelliklerine, yaşam tarzlarına ve şikayetlerine yönelik sorular içeren anket uygulanmıştır. Dışkıda parazit tanısı için Selofanlı bant yöntemi, nativ-lügol, sedimantasyon ve Modifiye kinyoun asit-fast, yöntemleri kullanılmıştır. Dışkı örnekleri mikroskopta incelenmiştir. H. pylori tanısı içinde alınan dışkı örneğinde H. pylori antijeni çalışılmıştır.
Bulgular: H.pylori pozitifliği %27.79 idi. H.pylori pozitif olanların 76.6%sı kadındı. H.pylori pozitif oranı 40 yaş ve üzerinde daha yüksekti (75.7%). H. pylori pozitifliği görülen hastaların büyük çoğunluğu evli (73.8), orta/düşük gelir düzeyine sahip (89.7%), düşük eğitim düzeyi olan (82.2%), köyde yaşayan (55.1%) ve çekirdek ailesiyle birlikte yaşamını sürdüren (72.2%) bireylerdi (p<0.001). H.pylori pozitifliği şehir şebeke suyu kullananlarda (40.2%) ve sebze ağırlıklı beslenenlerde daha yüksekti (75.7%) (p<0.001). Entamoeba histoloytica ve Enterobius vermicularis pozitifliği ile H.pylori pozitifliği arasında istatistiksel olarak önemli bir ilişki olduğu görüldü (sırasıyla p<0.05 p<0.001). Hesaplanan Odds ratio, Entamoeba histoloytica pozitifliğinde H.pylori pozitifliğinin 1,19 kat, Enterobius vermicularis pozitifliğinde H.pylori pozitifliğinin 11.27 kat daha fazla olduğunu gösterdi.
Sonuç: H pilori ile co-enfeksiyonun epidemiyolojisinin, klinik etkilerinin, tedavisinin ve kontrolünün iyi anlaşılması için daha geniş ve kapsamlı çalışmalara ihtiyaç vardır.

Keywords

Peptik Ülser, Helicobacter pylori, Barsak Parazitleri

Project Number

AR-1663

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