Damakta ve gingivada malin melanom: Nadir bir lokalizasyon

Year 2020, Volume: 3 Issue: 2, 52 - 56, 30.06.2020

Dua Cebeci , Şirin Yaşar , Yeşim Doğan Sabuncuoğlu Pembegul Güneş

https://doi.org/10.33204/mucosa.723907

Abstract

Primer malin melanom, melanositlerin çoğalmasından kaynaklanan nadir ve agresif bir neoplazmdır. Oral mukozal melanom, dokuları ağız boşluğunun diğer malin tümörlerinden daha kolay metastaz yapma ve istila etme eğiliminde olan nadir bir malinitedir. Bu tümörler ağız boşluğunun herhangi bir yerinde bulunmakta; bununla birlikte sert damak ve maksiller alveoler mukozayı daha sık etkilemektedir. Mukozal melanomların çoğu, bukalemun gibidir ve birçok melanositik lezyonla karışabilir. Genellikle erken evrelerde asemptomatiktirler ve pigmentli bir yama veya şişlik, ülserasyon, kanama veya dişlerin kaybı gibi belirtilerle, tanıyı geciktiren bir kitle olarak ortaya çıkarlar. Bu makalede 79 yaşında kadın hastada maksiller ön gingivada yerleşim gösteren oral malin melanom olgusunu sunuyoruz. Histopatolojik olarak tanıyı doğrulamak için imünohistokimya ve özel boyalar yapıldı.

Keywords

mukozal melanom, pigmentli lezyonlar, ağız boşluğu

Supporting Institution

destekleyen kurum yoktur

Malignant melanoma at the hard palate and gingiva: a rare localization

Abstract

Primary malignant melanoma is a rare and aggressive neoplasm that originates from the proliferation of melanocytes. Oral mucosal melanoma is a rare malignancy that tends to metastasize and to invade tissues more easily than other malignant tumors of the oral cavity. These tumors can be found anywhere in the oral cavity; however, they affect the hard palate and maxillary alveolar mucosa more frequently. Most mucosal melanomas are like chameleons and may be confused with many melanocytic lesions. In general, they are asymptomatic in the early stages and are presented as a mass that delays diagnosis until signs of a pigmented patch or swelling, ulceration, bleeding, or loosening of the teeth. In this article, we present a case of malignant melanoma of the maxillary anterior gingiva in a 79-year-old female patient. Immunohistochemistry and special staining were performed to

confirm the diagnosis histopathologicaly.

Keywords

mucosal melanoma, pigmented lesions, oral cavity

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