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Is vulvar purpura a component of plasma cell vulvitis or mucosal porosis?

Year 2022, Volume: 5 Issue: 1, 20 - 26, 31.05.2022
https://doi.org/10.33204/mucosa.1047554

Abstract

Here, we presented six women with isolated vulvar purpura. No associated lesions such as sclerosis, atrophy, or hypopigmentation were observed. All patients were in postmenopausal period. In this case series, we discussed if a non-blanching purpura could be a component of plasma cell vulvitis or “mucosal porosis”. The possibility of vulvar purpura was questioned as a mucosal equivalent of dermatoporosis which is an age-related degenerative process in the skin. While senile purpura is one of the morphological findings of dermatoporosis, vulvar purpura might be a part of “mucosal porosis”. Rapid response to topical estrogen was remarkable in all patients.

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Project Number

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Thanks

NAzila barahmani

References

  • Virgili A, Levratti A, Marzola A, Corazza M. Retrospective histopathologic reevaluation of 18 cases of plasma cell vulvitis. J Reprod Med 2005;50:3-7.
  • Virgili A, Corazza M, Minghetti S, Borghi A. Symptoms in plasma cell vulvitis: first observational cohort study on type, frequency and severity. Dermatology 2015;230:113-8.
  • Li Q, Leopold K, Carlson JA. Chronic vulvar purpura: persistent pigmented purpuric dermatitis (lichen aureus) of the vulva or plasma cell (Zoon’s) vulvitis? J Cutan Pathol 2003;30:572-6.
  • Kato T, Kuramoto Y, Tadaki T, Hashimoto K, Tagami H. Chronic vulvar purpura. Dermatologica 1990;180:174-6.
  • Kaya G, Saurat JH. Dermatoporosis: a chronic cutaneous insufficiency/fragility syndrome. Dermatology 2007;215:284-94.
  • Weyers W, Ende Y, Schalla W, Diaz-Cascajo C. Balanitis of Zoon: a clinicopathologic study of 45 cases. Am J Dermatopathol 2002;24:459-67.
  • Virgili A, Borghi A, Minghetti S, Corazza M. Comparative study on topical immunomodulatory and anti-inflammatory treatments for plasma cell vulvitis: long-term efficacy and safety. J Eur Acad Dermatol Venereol 2015;29:507-14.
  • Kim HK, Kang SY, Chung YJ, Kim JH, Kim MR. The recent review of the genitourinary syndrome of menopause. J Menopausal Med 2015;21:65-71.
  • Phillips NA, Bachmann GA. The genitourinary syndrome of menopause. Menopause 2021;28:579-88.

Vulvar purpura plazma hücreli vulvit ya da mukozal porozun bir komponenti olabilir mi?

Year 2022, Volume: 5 Issue: 1, 20 - 26, 31.05.2022
https://doi.org/10.33204/mucosa.1047554

Abstract

Bu yazıda, izole vulvar purpurası olan altı hastayı sunduk. Hiçbir hastada eşlik eden skleroz, atrofi ya da hipopigmentasyon gibi bulgular gözlenmedi. Hastaların tümü postmenopozal dönemde idi. Bu vaka serisinde, vulvada görülen purpurik lezyonların plazma hücreli vulvitin bir komponenti ya da yeni bir antite “mukozal poroz” olma olasılığını tartıştık. Vulvada görülen purpuranın, yaşlanmaya bağlı olarak deride tanımlanan dermatoporozun “mukozal” eşdeğeri olabileceği fikri ilginç olabilir. Senil purpura, dermatoporozun morfolojik bir bulgusu ise, belki de vulvar purpura mukozal porozun bir göstergesidir. Tüm hastalarda topikal östrojenle hızlı bir düzelme gözlenmesi bu teoriyi destekler niteliktedir.

Project Number

NA

References

  • Virgili A, Levratti A, Marzola A, Corazza M. Retrospective histopathologic reevaluation of 18 cases of plasma cell vulvitis. J Reprod Med 2005;50:3-7.
  • Virgili A, Corazza M, Minghetti S, Borghi A. Symptoms in plasma cell vulvitis: first observational cohort study on type, frequency and severity. Dermatology 2015;230:113-8.
  • Li Q, Leopold K, Carlson JA. Chronic vulvar purpura: persistent pigmented purpuric dermatitis (lichen aureus) of the vulva or plasma cell (Zoon’s) vulvitis? J Cutan Pathol 2003;30:572-6.
  • Kato T, Kuramoto Y, Tadaki T, Hashimoto K, Tagami H. Chronic vulvar purpura. Dermatologica 1990;180:174-6.
  • Kaya G, Saurat JH. Dermatoporosis: a chronic cutaneous insufficiency/fragility syndrome. Dermatology 2007;215:284-94.
  • Weyers W, Ende Y, Schalla W, Diaz-Cascajo C. Balanitis of Zoon: a clinicopathologic study of 45 cases. Am J Dermatopathol 2002;24:459-67.
  • Virgili A, Borghi A, Minghetti S, Corazza M. Comparative study on topical immunomodulatory and anti-inflammatory treatments for plasma cell vulvitis: long-term efficacy and safety. J Eur Acad Dermatol Venereol 2015;29:507-14.
  • Kim HK, Kang SY, Chung YJ, Kim JH, Kim MR. The recent review of the genitourinary syndrome of menopause. J Menopausal Med 2015;21:65-71.
  • Phillips NA, Bachmann GA. The genitourinary syndrome of menopause. Menopause 2021;28:579-88.
There are 9 citations in total.

Details

Primary Language English
Subjects Clinical Sciences
Journal Section Case Reports
Authors

Ayşe Kavak 0000-0002-4679-1181

Damlanur Sakız 0000-0002-2051-1049

Murat Yılmaz This is me 0000-0002-0034-9259

Nimet Yeşim Günay This is me 0000-0001-5537-8914

Levent Yaşar This is me 0000-0002-8679-2699

Project Number NA
Publication Date May 31, 2022
Published in Issue Year 2022 Volume: 5 Issue: 1

Cite

Vancouver Kavak A, Sakız D, Yılmaz M, Günay NY, Yaşar L. Is vulvar purpura a component of plasma cell vulvitis or mucosal porosis?. Mucosa. 2022;5(1):20-6.