Gebelik ve Posterior Reversible Ensefalopati Sendromu: Olgu Sunumu ve Literatürün Gözden Geçirilmesi
Year 2021,
Volume: 8 Issue: 3, 232 - 235, 28.12.2021
Gülsüm Saruhan Durmaz
,
Bergen Laleli
,
Ali Onur Arzık
,
Güray Koç
Abstract
Posterior revesible ensefalopati sendromu (PRES), nörolojik semptomlarla karakterize klinik ve radyolojik olarak geri dönüşümlü bir hastalıktır. Eklampsi, PRES’in nadir görülen nedenleri arasında yer almaktadır. Özellikle hipertansiyon ve proteinürisi olan gebelerde nöbetler görüldüğü zaman PRES ön tanıda düşünülmektedir. Hastanemize gebelik döneminde 3.trimesterde nöbet ile başvuran status epileptikus tanısı alan iki olguya sezaryen ile doğum yaptırılmış, antihipertansif ve antiepileptik tedavi verilmiştir. Bu dönemde yapılan nörolojik muayenelerinde bilinç bulanıklığı tespit edilmiş ve beyin MRG’leri PRES ile uyumlu saptanmıştır. Takiplerinde MRG lezyonları azalmış ve nöbet kontrolü sağlanmıştır. Bu yazıda eklampsi ve PRES birlikteliği olan iki olgunun sunulması ile, klinik ve radyolojik olarak PRES hastalığının literatür eşliğinde gözden geçirilmesi amaçlanmıştır.
References
- 1. Fischer M, Schmutzhard E. Posterior reversible encephalopathy syndrome. J Neurol. 2017;264(8):1608-16.
- 2. Hinchey J, Chaves C, Appignani B, et al. A reversible posterior leukoencephalopathy syndrome. N Engl J Med. 1996;334(8):494-500.
- 3. Masai K, Ueda Y, Naito H, et al. Atypical case of posterior reversible encephalopathy syndrome related to late onset postpartum eclampsia: A case report. Medicine (Baltimore). 2019;98(16):e15187.
- 4. Fugate JE, Rabinstein AA. Posterior reversible encephalopathy syndrome: clinical and radiological manifestations, pathophysiology, and outstanding questions. Lancet Neurol. 2015;14(9):914-25.
- 5. Pop A, Carbonnel M, Wang A, et al. Posterior reversible encephalopathy syndrome associated with reversible cerebral vasoconstriction syndrome in a patient presenting with postpartum eclampsia: A case report. J Gynecol Obstet Hum Reprod. 2019;48(6):431-4.
- 6. Shankar J, Banfield J. Posterior Reversible Encephalopathy Syndrome: A Review. Can Assoc Radiol J. 2017;68(2):147-53.
- 7. Marra A, Vargas M, Striano P, et al. Posterior reversible encephalopathy syndrome: the endothelial hypotheses. Med Hypotheses. 2014;82(5):619-22.
- 8. Janjua TK, Hassan M, Afridi HK, et al. Oxaliplatin-induced posterior reversible encephalopathy syndrome (PRES). BMJ Case Rep. 2017;2017: bcr2017221571.
- 9. Davi CB, Moraes BP, Lichtenfels BF, et al. Posterior reversible leukoencephalopathy syndrome (PRES) after kidney transplantation: a case report. J Bras Nefrol. 2018;40(1):91-4.
- 10. Verhaegen J, Peeters F, Debois P, et al. Posterior reversible encephalopathy syndrome as a complication of pre-eclampsia in the early postpartum period. BMJ Case Rep. 2019;12(7): e228954.
- 11. Shen T, Chen H, Jing J, et al. A study on clinical characteristics and the causes of missed diagnosis of reversible posterior leukoencephalopathy syndrome in eclampsia. Neurol Sci. 2019;40(9):1873-6.
- 12. Kastrup O, Gerwig M, Frings M, et al. Posterior reversible encephalopathy syndrome (PRES): electroencephalographic findings and seizure patterns. J Neurol. 2012;259(7):1383-9.
- 13. Fitzgerald RT, Santoro J, Hinduja A, et al. PRES and Epilepsy: A Potential Long-Term Consequence of a "Reversible" Syndrome. Neurologist. 2017;22(2):41-3.
- 14. Murray K, Amin U, Maciver S, et al. EEG Findings in Posterior Reversible Encephalopathy Syndrome. Clin EEG Neurosci. 2019;50(5):366-9.
- 15. Fang X, Wang H, Liu Z, et al. Posterior reversible encephalopathy syndrome in preeclampsia and eclampsia: The role of hypomagnesemia. Seizure. 2020;76:12-6.
- 16. Kisabay A OB, Sarı S, ve ark. Eklampsi ve PRES birlikteliği olan bir olgu nedeniyle antiepileptik tedavinin gözden geçirilmesi. Epilepsi. 2015;21(1):37-42.
- 17. Parikh NS, Schweitzer AD, Young RJ, et al. Corticosteroid therapy and severity of vasogenic edema in posterior reversible encephalopathy syndrome. J Neurol Sci. 2017;380:11-5.
Posterior Reversible Encephalopathy Syndrome and Pregnancy: A Case Report and Review of the Literature
Year 2021,
Volume: 8 Issue: 3, 232 - 235, 28.12.2021
Gülsüm Saruhan Durmaz
,
Bergen Laleli
,
Ali Onur Arzık
,
Güray Koç
Abstract
Posterior reversible encephalopathy syndrome (PRES) characterized by neurological symptoms, is a clinically and radiologically reversible disease. Eclampsia is one of the rare causes of PRES. PRES is especially considered when seizures are seen in pregnant women with hypertension and proteinuria. Two patients, admitted to our hospital with seizures in the third trimester of pregnancy, were diagnosed with status epilepticus, antihypertensive and antiepileptic treatment were administered and delivered with cesarean section. Encephalopathy was detected in patients during this period, brain MRIs revealed PRES. After treatment, MRI lesions regressed and the seizures were taken under control. In this article, it is aimed to present two cases with eclampsia and PRES coexistence and review PRES disease clinically and radiologically.
References
- 1. Fischer M, Schmutzhard E. Posterior reversible encephalopathy syndrome. J Neurol. 2017;264(8):1608-16.
- 2. Hinchey J, Chaves C, Appignani B, et al. A reversible posterior leukoencephalopathy syndrome. N Engl J Med. 1996;334(8):494-500.
- 3. Masai K, Ueda Y, Naito H, et al. Atypical case of posterior reversible encephalopathy syndrome related to late onset postpartum eclampsia: A case report. Medicine (Baltimore). 2019;98(16):e15187.
- 4. Fugate JE, Rabinstein AA. Posterior reversible encephalopathy syndrome: clinical and radiological manifestations, pathophysiology, and outstanding questions. Lancet Neurol. 2015;14(9):914-25.
- 5. Pop A, Carbonnel M, Wang A, et al. Posterior reversible encephalopathy syndrome associated with reversible cerebral vasoconstriction syndrome in a patient presenting with postpartum eclampsia: A case report. J Gynecol Obstet Hum Reprod. 2019;48(6):431-4.
- 6. Shankar J, Banfield J. Posterior Reversible Encephalopathy Syndrome: A Review. Can Assoc Radiol J. 2017;68(2):147-53.
- 7. Marra A, Vargas M, Striano P, et al. Posterior reversible encephalopathy syndrome: the endothelial hypotheses. Med Hypotheses. 2014;82(5):619-22.
- 8. Janjua TK, Hassan M, Afridi HK, et al. Oxaliplatin-induced posterior reversible encephalopathy syndrome (PRES). BMJ Case Rep. 2017;2017: bcr2017221571.
- 9. Davi CB, Moraes BP, Lichtenfels BF, et al. Posterior reversible leukoencephalopathy syndrome (PRES) after kidney transplantation: a case report. J Bras Nefrol. 2018;40(1):91-4.
- 10. Verhaegen J, Peeters F, Debois P, et al. Posterior reversible encephalopathy syndrome as a complication of pre-eclampsia in the early postpartum period. BMJ Case Rep. 2019;12(7): e228954.
- 11. Shen T, Chen H, Jing J, et al. A study on clinical characteristics and the causes of missed diagnosis of reversible posterior leukoencephalopathy syndrome in eclampsia. Neurol Sci. 2019;40(9):1873-6.
- 12. Kastrup O, Gerwig M, Frings M, et al. Posterior reversible encephalopathy syndrome (PRES): electroencephalographic findings and seizure patterns. J Neurol. 2012;259(7):1383-9.
- 13. Fitzgerald RT, Santoro J, Hinduja A, et al. PRES and Epilepsy: A Potential Long-Term Consequence of a "Reversible" Syndrome. Neurologist. 2017;22(2):41-3.
- 14. Murray K, Amin U, Maciver S, et al. EEG Findings in Posterior Reversible Encephalopathy Syndrome. Clin EEG Neurosci. 2019;50(5):366-9.
- 15. Fang X, Wang H, Liu Z, et al. Posterior reversible encephalopathy syndrome in preeclampsia and eclampsia: The role of hypomagnesemia. Seizure. 2020;76:12-6.
- 16. Kisabay A OB, Sarı S, ve ark. Eklampsi ve PRES birlikteliği olan bir olgu nedeniyle antiepileptik tedavinin gözden geçirilmesi. Epilepsi. 2015;21(1):37-42.
- 17. Parikh NS, Schweitzer AD, Young RJ, et al. Corticosteroid therapy and severity of vasogenic edema in posterior reversible encephalopathy syndrome. J Neurol Sci. 2017;380:11-5.