The Agreement of Iridocorneal Angle Parameters between Pentacam and Two Different Optical Coherence Tomography Devices in a Healthy Population

Year 2022, Volume: 9 Issue: 2, 153 - 157, 24.08.2022

Ahmet Kaderli , Aylin Karalezli

https://doi.org/10.47572/muskutd.888556

Abstract

To evaluate the compatibility and consistency of iridocorneal angle (ICA) measurements detected with Pentacam (Oculus, Inc., Germany), RTVue (Optovue Inc., Freemont, USA) and Spectralis (Heidelberg GmbH, Germany) devices. Twenty-two eyes of 22 healthy participants were evaluated retrospectively. In Pentacam, measurements were taken automatically in each eye at 3 and 9 o'clock (nasal and temporal), and trabecular-iris angle values were recorded. In RTVue and Spectralis anterior segment optical coherence tomographies, the parameters of anterior chamber recess angle (ACA), scleral spur angle (SSA) and angle opening distance from 500 µm distance (AOD500) were recorded. All measurements were taken under similar lighting conditions. Cases under the age of 18 years, history of previous ocular surgery orophthalmic laser, refractive errors that may alter ICA measurements, fixation abilities, insufficient anterior segment image quality or cases with intraocular pressure above 21 mmHg during examinations were excluded from the study. All devices were found to be consistent with each other in terms of ACA-SSA in both nasal and temporal quadrants (for temporal-nasal quadrants respectively ICC; 0.871, 0.837; 0.872, 0.839). According to the Bland-Altman analysis, when Pentacam is taken as the reference device, as the ACA value widens, both RTVue and Spectralis measurements show higher agreement. While ACA degrees were statistically similar in both the nasal and temporal quadrants for Pentacam and RTVue, it was found narrower in Spectralis (for nasal quadrant p=0.003, for temporal quadrant p=0.007). Although there was a good consistency between the AOD500 values between RTVue and Spectralis, (for temporal quadrant ICC: 0.825, for nasal quadrant ICC: 0.882) it was determined that Spectralis showed higher results than RTVue (p˂0.001). Although Pentacam, RTVue and Spectralis measurements are found to be consistent with each other for the evaluation of ICA, considering the differences between the devices of both ACA-SSA and AAU500 values, it may be considered that the relevant devices may not be used inter changeably in patient follow-ups.

Keywords

Anterior Chamber Angle, Anterior Opening Distance, Anterior Segment OCT, Pentacam

Project Number

Yok.

Sağlıklı Popülasyonda İridokorneal Açı Parametrelerinin Pentacam ve İki Farklı Optik Koherens Tomografi Cihazları Arasındaki Uyumluluğu

Abstract

Pentacam (Oculus, Inc., Almanya), RTVue (OptovueInc., Freemont, ABD) ve Spectralis (Heidelberg GmbH, Almanya) cihazları ile saptanan iridokorneal açı (İKA) ölçümlerinin tutarlılık ve uyumluluğunun değerlendirilmesi amaçlanmıştır. 22 sağlıklı katılımcının 22 gözü retrospektif olarak değerlendirilmiştir. Pentacam cihazında ölçümler her gözde saat 3 ve 9 kadranlarda (nazal ve temporal) otomatik olarak alınmış olup, trabeküler-iris açı değerleri kaydedilmiştir. RTVue ve Spectralis ön segment optik koherens tomografilerinde (ÖS-OKT) ise, ön kamara girintisi açısı (ÖKGA), skleral mahmuz açısı (SMA) ve 500 µm uzaklıktan açı açılış uzaklığı (AAU500) parametreleri kaydedilmiştir. Tüm ölçümler benzer aydınlatma koşulları altında gerçekleştirilmiştir. 18 yaş altı olgular, geçirilmiş oküler cerrahi veya lazer öyküsü, İKA ölçümleri üzerinde farklılık yaratabilecek refraktif kusurlar, fiksasyon bozukluğu ya da yetersiz ön segment görüntü kalitesi, muayene esnasında GİB’si 21 mmHg üzerinde olan olgular çalışma dışında bırakılmıştır. Tüm cihazlar hem nazal hem temporal kadranlarda ÖKGA-SMA yönünden birbirleriyle uyumlu bulunmuştur (sırasıyla temporal-nazal ICC; 0.871, 0.837; 0.872, 0.839). Bland-Altman analizine göre Pentacam referans cihaz olarak alındığında, ÖKGA değeri yükseldikçe hem RTVue hem de Spectralis ölçümleri daha yüksek uyumluluk göstermektedir. ÖKGA, Pentacam ve RTVue için hem nazal hem temporal kadranlarda istatistiksel benzer sonuçlar verirken, Spectralis’te daha dar sonuçlar vermiştir (nazal kadran p=0.003, temporal kadran p=0.007). RTVue ve Spectralis arasında AAU500 değerleri arasında iyi tutarlılık görülse de (temporal kadran ICC: 0.825, nazal kadran ICC: 0.882), Spectralis’in RTVue’ya göre daha yüksek sonuçlar gösterdiği belirlenmiştir (p˂0.001). IKA değerlendirilmesi için Pentacam, RTVue ve Spectralis ölçümlerinin birbirleriyle uyumlu olduğu saptansa da gerek ÖKGA-SMA, gerekse AAU500 değerlerinin cihazlar arası farklılığı göz önüne alındığında, hasta takibinde ilgili cihazların birbirleri yerine kullanılmasının uygun olmayabileceği düşünülebilir. 

Keywords

Açı Açılış Uzaklığı, Ön Kamara Açısı, Ön Segment OKT, Pentacam

Supporting Institution

Yok.

Project Number

Yok.

Thanks

Yok.

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