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Hypereosinophilic Syndrome Presenting As Pruriginous Erythroderma

Year 2011, Volume: 28 Issue: 1, - , 15.02.2012

Abstract

ABSTRACT
Hypereosinophilic syndrome (HES) is a multi-organ disease (heart, eye, lungs or nervous tissue). The etiology and pathogenesis of HES is still unknown. It is characterized by 1500 eosinophils/µl of eosinophils in peripheral blood observed during at least six months without any evidence for other known causes of eosinophilia. The skin manifestations of the disease were pruritic, erythematous macules, papules, plaques or nodules and rarely urticaria, angioedema, livedo reticularis, eosinophilic cellulitis, cutaneous necrotizing eosinophilic vasculitis, retiform purpura. Among the skin lesions erythroderma is a rare complication of HES and has only been reported in a few cases (Launay et al., 2002, Granjo et al., 2002). We report here a 78-yrs-old man with pruriginous erythroderma leading to the diagnosis of hypereosinophilic syndrome. In dermatological examination erythrodermia and mild desquamation was noticed entire the body surface with bilateral ectropion.
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References

  • Butterfield, J.H. 2007. Treatment of hypereosinophilic syndromes with prednisone, hydroxyurea, and interfereon. Immunol. Allergy Clin. North Am. 27, 493-518.
  • Granjo, E., Lima, M. Lopes, J.M. 2002. Chronic eosinophilic leukaemia presenting with erythroderma, mild eosinophila and hyper-1gE: clinical, immunilogical and cytogenetic features and therapeutic approach. A case report. Acta. Haematol. 107, 108-112.
  • Launay D, Catteau B, Dubost-.Brama, A. 2002. A four-year history of pruriginous erythroderma leading to the diagnosis of idiopathic hyperesinophilic syndrome. Acta. Derm. Venereol. 82, 376-378.
  • Leiferman, K.M., Gleich, G.J., Peters, M.S. 2007. Dermatologic manifestations of the hypereosinophilic syndromes. Immunol. Allergy. Clin. North Am. 27, 415-441.
  • Tefferi, A. 2005. Modern diagnosis and treatment of primary eosinophilia. Acta. Haematol. 4, 52-56.
Year 2011, Volume: 28 Issue: 1, - , 15.02.2012

Abstract

References

  • Butterfield, J.H. 2007. Treatment of hypereosinophilic syndromes with prednisone, hydroxyurea, and interfereon. Immunol. Allergy Clin. North Am. 27, 493-518.
  • Granjo, E., Lima, M. Lopes, J.M. 2002. Chronic eosinophilic leukaemia presenting with erythroderma, mild eosinophila and hyper-1gE: clinical, immunilogical and cytogenetic features and therapeutic approach. A case report. Acta. Haematol. 107, 108-112.
  • Launay D, Catteau B, Dubost-.Brama, A. 2002. A four-year history of pruriginous erythroderma leading to the diagnosis of idiopathic hyperesinophilic syndrome. Acta. Derm. Venereol. 82, 376-378.
  • Leiferman, K.M., Gleich, G.J., Peters, M.S. 2007. Dermatologic manifestations of the hypereosinophilic syndromes. Immunol. Allergy. Clin. North Am. 27, 415-441.
  • Tefferi, A. 2005. Modern diagnosis and treatment of primary eosinophilia. Acta. Haematol. 4, 52-56.
There are 5 citations in total.

Details

Primary Language English
Journal Section Internal Medical Sciences
Authors

Günseli Pancar

Müge Özden This is me

Fatma Aydın This is me

Nilgün Şentürk This is me

M. Tayyar Cantürk This is me

Ahmet Yaşar Turanlı This is me

Publication Date February 15, 2012
Submission Date November 1, 2010
Published in Issue Year 2011 Volume: 28 Issue: 1

Cite

APA Pancar, G., Özden, M., Aydın, F., Şentürk, N., et al. (2012). Hypereosinophilic Syndrome Presenting As Pruriginous Erythroderma. Journal of Experimental and Clinical Medicine, 28(1). https://doi.org/10.5835/jecm.v28i1.1263
AMA Pancar G, Özden M, Aydın F, Şentürk N, Cantürk MT, Turanlı AY. Hypereosinophilic Syndrome Presenting As Pruriginous Erythroderma. J. Exp. Clin. Med. February 2012;28(1). doi:10.5835/jecm.v28i1.1263
Chicago Pancar, Günseli, Müge Özden, Fatma Aydın, Nilgün Şentürk, M. Tayyar Cantürk, and Ahmet Yaşar Turanlı. “Hypereosinophilic Syndrome Presenting As Pruriginous Erythroderma”. Journal of Experimental and Clinical Medicine 28, no. 1 (February 2012). https://doi.org/10.5835/jecm.v28i1.1263.
EndNote Pancar G, Özden M, Aydın F, Şentürk N, Cantürk MT, Turanlı AY (February 1, 2012) Hypereosinophilic Syndrome Presenting As Pruriginous Erythroderma. Journal of Experimental and Clinical Medicine 28 1
IEEE G. Pancar, M. Özden, F. Aydın, N. Şentürk, M. T. Cantürk, and A. Y. Turanlı, “Hypereosinophilic Syndrome Presenting As Pruriginous Erythroderma”, J. Exp. Clin. Med., vol. 28, no. 1, 2012, doi: 10.5835/jecm.v28i1.1263.
ISNAD Pancar, Günseli et al. “Hypereosinophilic Syndrome Presenting As Pruriginous Erythroderma”. Journal of Experimental and Clinical Medicine 28/1 (February 2012). https://doi.org/10.5835/jecm.v28i1.1263.
JAMA Pancar G, Özden M, Aydın F, Şentürk N, Cantürk MT, Turanlı AY. Hypereosinophilic Syndrome Presenting As Pruriginous Erythroderma. J. Exp. Clin. Med. 2012;28. doi:10.5835/jecm.v28i1.1263.
MLA Pancar, Günseli et al. “Hypereosinophilic Syndrome Presenting As Pruriginous Erythroderma”. Journal of Experimental and Clinical Medicine, vol. 28, no. 1, 2012, doi:10.5835/jecm.v28i1.1263.
Vancouver Pancar G, Özden M, Aydın F, Şentürk N, Cantürk MT, Turanlı AY. Hypereosinophilic Syndrome Presenting As Pruriginous Erythroderma. J. Exp. Clin. Med. 2012;28(1).