Sorafenib-induced pancreatitis

Year 2015, Volume: 32 Issue: 3, 133 - 135, 17.11.2015

Talat Ayyıldız , Taner Aydın Ahmet Tarık Eminler , Çınar Yıldırım Kader Irak Murat Kıyıcı Selim Gürel Selim Giray Nak Macit Gülten Enver Dolar

Abstract

Sorafenib is an inhibitor of multikinase proteins which is used for metastatic renal cell carcinoma and advanced stage hepatocellular carcinoma. Its side effects include serum amylase and lipase elevations anticipated to occur within first weeks of treatment but clinically and radiologically evident acute pancreatitis develops rarely. Five cases of acute pancreatitis have been reported in literature until date. The case we described here is the sixth case of clinically diagnosed acute pancreatitis.

Keywords

Hepatocellular carcinoma, Pancreatitis, Sorafenib, Tyrosine kinase inhibitor

References

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