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Celiac disease in an obese child with down syndrome

Year 2017, Volume: 34 Issue: 2, 133 - 135, 08.09.2017

Abstract

Patients with Down syndrome are predisposed to autoimmune disease and have

a higher risk for type 1 diabetes, autoimmune thyroid disorders, alopecia, vitiligo,

hypoparathyroidism and celiac disease. Diarrhea and malabsorption represent

the typical presentation of celiac disease, while obesity or weight gain are

uncommon in young children. We report an 8-year-old obese girl with Down

syndrome who was diagnosed as celiac disease in the absence of signs and

symptoms. We would suggest that even in absence of signs and symptoms, the

children with Down syndrome should be screened annually for celiac disease









even owing to obesity.







References

  • Kinik, S.T., Ozcay, F., Varan, B., 2006. Type I diabetes mellitus, Hashimoto’s thyroiditis and celiac disease in an adolescent with Down syndrome. Pediatr. Int. 48, 433-435. Book, L., Hart, A., Black., J., Feolo, M., Zone, J.J., Neuhausen, S.L., 2001. Prevalence and clinical characteristics of celiac disease in Down syndrome in a US study. Am. J. Med. Genet. 98, 70-74. Cogulu, O., Ozkinay, F., Gunduz, C., Cankaya, T., Aydogdu, S., Ozgenc, F., Kutukculer, N., Ozkinay, C., 2003. Celiac disease in children with Down syndrome: importance of following up and serological screening. Pediatr. Int. 45, 395-359. George, E.K., Mearin, M.L., Bouquet, J., von Blomberg, B.M., Stapel, S.O., van Elburg, R.M., de Graaf, E.A., 1996. High frequency of celiac disease in Down syndrome. J. Pediatr. 128, 555-557. Jansson, U., Johansson, C., 1995. Down syndrome and celiae disease. J. Pediatr. Gastroenterol. Nutr. 21, 443-445. Arslan, N., Esen, I., Demircioglu, F., Yilmaz, S., Unuvar, T., Bober, E., 2009. The changing face of celiac disease: A girl with obesity and celiac disease. J. Paediatr. Child Health. 45, 317-318. doi: 10.1111/j.1440-1754.2009.01512.x. Balamtekin, N., Demir, H., Baysoy, G., Uslu, N., Yüce, A., 2011. Obesity in adolescents with celiac disease: Two adolescents and two different presentations. Turk J. Pediatr. 53, 314-316. Conti, Nibali, S., Magazzù, G., De Luca, F., 1987. Obesity in a child with untreated coeliac disease. Helv. Paediatr. Acta. 42, 45-48. Venkatasubramani, N., Telega, G., Werlin, S.L., 2010. Obesity in pediatric celiac disease. J. Pediatr. Gastroenterol. Nutr. 51, 295- 297. doi: 10.1097/MPG.0b013e3181d1365a. Semeraro, L.A., Barwick, K.W., Gryboski, J.D. 1986. Obesity in celiac sprue. J. Clin. Gastroenterol. 8, 177-180.
Year 2017, Volume: 34 Issue: 2, 133 - 135, 08.09.2017

Abstract

References

  • Kinik, S.T., Ozcay, F., Varan, B., 2006. Type I diabetes mellitus, Hashimoto’s thyroiditis and celiac disease in an adolescent with Down syndrome. Pediatr. Int. 48, 433-435. Book, L., Hart, A., Black., J., Feolo, M., Zone, J.J., Neuhausen, S.L., 2001. Prevalence and clinical characteristics of celiac disease in Down syndrome in a US study. Am. J. Med. Genet. 98, 70-74. Cogulu, O., Ozkinay, F., Gunduz, C., Cankaya, T., Aydogdu, S., Ozgenc, F., Kutukculer, N., Ozkinay, C., 2003. Celiac disease in children with Down syndrome: importance of following up and serological screening. Pediatr. Int. 45, 395-359. George, E.K., Mearin, M.L., Bouquet, J., von Blomberg, B.M., Stapel, S.O., van Elburg, R.M., de Graaf, E.A., 1996. High frequency of celiac disease in Down syndrome. J. Pediatr. 128, 555-557. Jansson, U., Johansson, C., 1995. Down syndrome and celiae disease. J. Pediatr. Gastroenterol. Nutr. 21, 443-445. Arslan, N., Esen, I., Demircioglu, F., Yilmaz, S., Unuvar, T., Bober, E., 2009. The changing face of celiac disease: A girl with obesity and celiac disease. J. Paediatr. Child Health. 45, 317-318. doi: 10.1111/j.1440-1754.2009.01512.x. Balamtekin, N., Demir, H., Baysoy, G., Uslu, N., Yüce, A., 2011. Obesity in adolescents with celiac disease: Two adolescents and two different presentations. Turk J. Pediatr. 53, 314-316. Conti, Nibali, S., Magazzù, G., De Luca, F., 1987. Obesity in a child with untreated coeliac disease. Helv. Paediatr. Acta. 42, 45-48. Venkatasubramani, N., Telega, G., Werlin, S.L., 2010. Obesity in pediatric celiac disease. J. Pediatr. Gastroenterol. Nutr. 51, 295- 297. doi: 10.1097/MPG.0b013e3181d1365a. Semeraro, L.A., Barwick, K.W., Gryboski, J.D. 1986. Obesity in celiac sprue. J. Clin. Gastroenterol. 8, 177-180.
There are 1 citations in total.

Details

Journal Section Basic Medical Sciences
Authors

Selim Dereci

Ozgur Pirgon This is me

Tugba Gursoy Koca This is me

Mustafa Akcam This is me

Publication Date September 8, 2017
Submission Date September 7, 2017
Acceptance Date May 10, 2015
Published in Issue Year 2017 Volume: 34 Issue: 2

Cite

APA Dereci, S., Pirgon, O., Gursoy Koca, T., Akcam, M. (2017). Celiac disease in an obese child with down syndrome. Journal of Experimental and Clinical Medicine, 34(2), 133-135.
AMA Dereci S, Pirgon O, Gursoy Koca T, Akcam M. Celiac disease in an obese child with down syndrome. J. Exp. Clin. Med. September 2017;34(2):133-135.
Chicago Dereci, Selim, Ozgur Pirgon, Tugba Gursoy Koca, and Mustafa Akcam. “Celiac Disease in an Obese Child With down Syndrome”. Journal of Experimental and Clinical Medicine 34, no. 2 (September 2017): 133-35.
EndNote Dereci S, Pirgon O, Gursoy Koca T, Akcam M (September 1, 2017) Celiac disease in an obese child with down syndrome. Journal of Experimental and Clinical Medicine 34 2 133–135.
IEEE S. Dereci, O. Pirgon, T. Gursoy Koca, and M. Akcam, “Celiac disease in an obese child with down syndrome”, J. Exp. Clin. Med., vol. 34, no. 2, pp. 133–135, 2017.
ISNAD Dereci, Selim et al. “Celiac Disease in an Obese Child With down Syndrome”. Journal of Experimental and Clinical Medicine 34/2 (September 2017), 133-135.
JAMA Dereci S, Pirgon O, Gursoy Koca T, Akcam M. Celiac disease in an obese child with down syndrome. J. Exp. Clin. Med. 2017;34:133–135.
MLA Dereci, Selim et al. “Celiac Disease in an Obese Child With down Syndrome”. Journal of Experimental and Clinical Medicine, vol. 34, no. 2, 2017, pp. 133-5.
Vancouver Dereci S, Pirgon O, Gursoy Koca T, Akcam M. Celiac disease in an obese child with down syndrome. J. Exp. Clin. Med. 2017;34(2):133-5.