Two multiple sclerosis cases developed herpes zoster during use of fingolimod

Year 2018, Volume: 35 Issue: 1, 27 - 30, 25.10.2019

Murat Terzi , Taşkın Duman Sedat Şen Murat Güntel Nalan Örtücü Şen

Abstract

Multiple sclerosis (MS) is an inflammatory, demyelinating disease of the central
nervous system. Immunosuppressive and immunomodulating drugs are used
during disease monitoring. Fingolimod is one of the immunomodulatory treat-
ments used in MS patients. It is a therapeutic agent acting on lymphocytes. La-
tent varicella-zoster virus infections may occur in MS patients receiving fingo-
limod therapy. In this article, the information of two cases with varicella-zoster
virus reactivation during fingolimod use were presented.

Keywords

Fingolimod, Multiple sclerosis, Varicella-zoster virus reactivation, Zoster

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