Year 2022,
Volume: 39 Issue: 1, 283 - 286, 01.01.2022
Nergis Ekmen
,
Nirgül Bilger
Derya Kirman
,
Hadi Sasani
References
- 1. Lichtenberger P, Rosa-Cunha I, Morris M, Nishida S, Akpinar E, Gaitan J, Tzakis A, Doblecki-Lewis S. Hyperinfection strongyloidiasis in a liver transplant recipient treated with parenteral ivermectin. Transpl Infect Dis. 2009; 11(2): 137-142.
- 2. Vilela EG, Clemente WT, Mira RR, Torres HO, Veloso LF, Fonseca LP, de Carvalho E Fonseca LR, Franca Md, Lima AS. Strongyloides stercoralis hyperinfection syndrome after liver transplantation: case report and literature review. Transpl Infect Dis. 2009; 11(2): 132-136.
- 3. Ofosu A, Higgins J, Frye JS, Kumari R, Barakat MT. Strongyloides Superinfection After Liver Transplantion. Dig Dis. Sci 2020. doi: 10.1007/s10620-020-06696-3.
- 4. Arkell P, Pan D, Riley P, Cooper P, MacPhee I, Cosgrove C, Brincat S. Should prospective renal transplant recipients be screened for Strongyloides stercoralis? Clin Kidney J. 2020; 14(2): 725-727.
- 5. Karanam L SK, Basavraj GK, Papireddy CKR. Strongyloides stercoralis Hyper infection Syndrome. Indian J Surg. 2020: 1-5.
- 6. Morgan JS, Scha¡nerW, StoneWJ. Opportunistic strongyloidiasis in renal transplant recipients. Transplantation. 1986; 42(5): 518-524.
- 7. Lim S, Katz K, Krajden S, et al. Complicated and fatal Strongyloides infection in Canadians: risk factors, diagnosis and management. CMAJ. 2004; 171(5): 479–484.
- 8. Montes M, Sawhney C, Barros N. Strongyloides stercoralis: there but not seen. Curr Opin Infect Dis. 2010; 23(5): 500–504.
- 9. Nutman TB. Human infection with Strongyloides stercoralis and other related Strongyloides species. Parasitology. 2017; 144(3): 263–273
- 10. Buonfrate D, Requena-Mendez A, Angheben A et al. Severe strongyloidiasis: a systematic review of case reports. BMC Infect Dis. 2013; 13: 78.
- 11. Archibald LK, Beeching NJ, Gill GV, Bailey JW, Bell DR. Albendazole is e¡ective treatment for chronic strongyloidiasis. Q J Med. 1993; 86(3): 191-195.
- 12. Liepman M. Disseminated Strongyloides stercoralis. A complication of immunosuppression. JAMA. 1975; 231(4): 387-388.
- 13. Chaudhuri B, Nanos S, Soco JN, McGrew EA. Disseminated Strongyloides stercoralis infestation detected by sputum cytology. Acta Cytol. 1980; 24(4): 360-362.
- 14. Schaeffer MW, Buell JF, Gupta M, Conway GD, Akhter SA,Wagoner LE. Strongyloides hyperinfection syndrome after heart transplantation: case report and review of the literature. J Heart Lung Transplant. 2004; 23(7): 905-911.
- 15. Rodriguez-Hernandez MJ, Ruiz-Perez-Pipaon M, Cañas E, Bernal C, Gavilan F. Strongyloides stercoralis hyperinfection transmitted by liver allograft in a transplant recipient. Am J Transplant. 2009; 9(11): 2637-2640.
- 16. Hamilton KW, Abt PL, Rosenbach MA, Bleicher MB, Levine MS, Mehta J, Montgomery SP, Hasz RD, Bono BR, Tetzlaff MT, Mildiner-Early S, Introcaso CE, Blumberg EA. Donor-derived Strongyloides stercoralis infections in renal transplant recipients. Transplantation. 2011; 91(9): 1019-1024.
- 17. Brügemann J, Kampinga GA, Riezebos-Brilman A, Stek CJ, Edel JP, van der Bij W, Sprenger HG, Zijlstra F. Two donor-related infections in a heart transplant recipient: one common, the other a tropical surprise. J Heart Lung Transplant. 2010; 29(12): 1433-1437.
- 18. Abanyie FA, Gray EB, Delli Carpini KW, Yanofsky A, McAuliffe I, Rana M, Chin-Hong PV, Barone CN, Davis JL, Montgomery SP, Huprikar S. Donor-derived Strongyloides stercoralis infection in solid organ transplant recipients in the United States, 2009-2013. Am J Transplant. 2015; 15(5): 1369-1375.
- 19. Elzein F, Albahili H, Bahloul A, Alonazi T, Alghamdi A, Alsufyani E, Musa A, Alsaeed M. Transplant-related strongyloidiasis in solid organ transplant recipients in Saudi Arabia and the Gulf Cooperation Council countries. Int J Infect Dis. 2020; 93: 133-138.
- 20. Alibrahim F, AlAlwan A, Al Thiab K, Alawaji A, Alwan B, Taher L, Bosaeed M. Strongyloides and hookworms co-infection in a liver transplant patient. IDCases. 2021; 24:e01060.
- 21. Camargo JF, Simkins J, Anjan S, Guerra G, Vianna R, Salama S, Albright C, Shipman E, Montoya J, Morris MI, Abbo LM. Implementation of a Strongyloides screening strategy in solid organ transplant donors and recipients. Clin Transplant. 2019; 33(4): e13497.
- 22. Gómez-Junyent J, Paredes-Zapata D, de las Parras ER, González-Costello J, Ruiz-Arranz Á, Cañizares R, Saugar JM, Muñoz J. Real-Time Polymerase Chain Reaction in Stool Detects Transmission of Strongyloides stercoralis from an Infected Donor to Solid Organ Transplant Recipients. Am J Trop Med Hyg. 2016; 94(4): 897-899.
Multiorgan failure due to strongyloides infection in liver transplant recipient: A case report and literature review
Year 2022,
Volume: 39 Issue: 1, 283 - 286, 01.01.2022
Nergis Ekmen
,
Nirgül Bilger
Derya Kirman
,
Hadi Sasani
Abstract
Strongyloidasis is caused by an intestinal nematode Strongyloides stercoralis which is widely distributed in tropical and subtropical countries. In immunocompetent individuals, Strongloides stercoralis infection usually does not produce any symptoms or causes gastrointestinal, cardiopulmonary, or skin symptoms. However, in some patients especially immunsupressive (e.g post-transplant, taking exogenous corticosteroids), its infection associated with severe and life-threatening disease like hyperinfection syndrome and disseminated tissue infestation. The limitation of diagnostic test make it challenging to diagnose strongyloidasis. Therefore, it is important to suspect infection of Strongyloides stercoralis. We describe a case of Strongiloides infection with a fatal outcome in liver transplant recipient.
References
- 1. Lichtenberger P, Rosa-Cunha I, Morris M, Nishida S, Akpinar E, Gaitan J, Tzakis A, Doblecki-Lewis S. Hyperinfection strongyloidiasis in a liver transplant recipient treated with parenteral ivermectin. Transpl Infect Dis. 2009; 11(2): 137-142.
- 2. Vilela EG, Clemente WT, Mira RR, Torres HO, Veloso LF, Fonseca LP, de Carvalho E Fonseca LR, Franca Md, Lima AS. Strongyloides stercoralis hyperinfection syndrome after liver transplantation: case report and literature review. Transpl Infect Dis. 2009; 11(2): 132-136.
- 3. Ofosu A, Higgins J, Frye JS, Kumari R, Barakat MT. Strongyloides Superinfection After Liver Transplantion. Dig Dis. Sci 2020. doi: 10.1007/s10620-020-06696-3.
- 4. Arkell P, Pan D, Riley P, Cooper P, MacPhee I, Cosgrove C, Brincat S. Should prospective renal transplant recipients be screened for Strongyloides stercoralis? Clin Kidney J. 2020; 14(2): 725-727.
- 5. Karanam L SK, Basavraj GK, Papireddy CKR. Strongyloides stercoralis Hyper infection Syndrome. Indian J Surg. 2020: 1-5.
- 6. Morgan JS, Scha¡nerW, StoneWJ. Opportunistic strongyloidiasis in renal transplant recipients. Transplantation. 1986; 42(5): 518-524.
- 7. Lim S, Katz K, Krajden S, et al. Complicated and fatal Strongyloides infection in Canadians: risk factors, diagnosis and management. CMAJ. 2004; 171(5): 479–484.
- 8. Montes M, Sawhney C, Barros N. Strongyloides stercoralis: there but not seen. Curr Opin Infect Dis. 2010; 23(5): 500–504.
- 9. Nutman TB. Human infection with Strongyloides stercoralis and other related Strongyloides species. Parasitology. 2017; 144(3): 263–273
- 10. Buonfrate D, Requena-Mendez A, Angheben A et al. Severe strongyloidiasis: a systematic review of case reports. BMC Infect Dis. 2013; 13: 78.
- 11. Archibald LK, Beeching NJ, Gill GV, Bailey JW, Bell DR. Albendazole is e¡ective treatment for chronic strongyloidiasis. Q J Med. 1993; 86(3): 191-195.
- 12. Liepman M. Disseminated Strongyloides stercoralis. A complication of immunosuppression. JAMA. 1975; 231(4): 387-388.
- 13. Chaudhuri B, Nanos S, Soco JN, McGrew EA. Disseminated Strongyloides stercoralis infestation detected by sputum cytology. Acta Cytol. 1980; 24(4): 360-362.
- 14. Schaeffer MW, Buell JF, Gupta M, Conway GD, Akhter SA,Wagoner LE. Strongyloides hyperinfection syndrome after heart transplantation: case report and review of the literature. J Heart Lung Transplant. 2004; 23(7): 905-911.
- 15. Rodriguez-Hernandez MJ, Ruiz-Perez-Pipaon M, Cañas E, Bernal C, Gavilan F. Strongyloides stercoralis hyperinfection transmitted by liver allograft in a transplant recipient. Am J Transplant. 2009; 9(11): 2637-2640.
- 16. Hamilton KW, Abt PL, Rosenbach MA, Bleicher MB, Levine MS, Mehta J, Montgomery SP, Hasz RD, Bono BR, Tetzlaff MT, Mildiner-Early S, Introcaso CE, Blumberg EA. Donor-derived Strongyloides stercoralis infections in renal transplant recipients. Transplantation. 2011; 91(9): 1019-1024.
- 17. Brügemann J, Kampinga GA, Riezebos-Brilman A, Stek CJ, Edel JP, van der Bij W, Sprenger HG, Zijlstra F. Two donor-related infections in a heart transplant recipient: one common, the other a tropical surprise. J Heart Lung Transplant. 2010; 29(12): 1433-1437.
- 18. Abanyie FA, Gray EB, Delli Carpini KW, Yanofsky A, McAuliffe I, Rana M, Chin-Hong PV, Barone CN, Davis JL, Montgomery SP, Huprikar S. Donor-derived Strongyloides stercoralis infection in solid organ transplant recipients in the United States, 2009-2013. Am J Transplant. 2015; 15(5): 1369-1375.
- 19. Elzein F, Albahili H, Bahloul A, Alonazi T, Alghamdi A, Alsufyani E, Musa A, Alsaeed M. Transplant-related strongyloidiasis in solid organ transplant recipients in Saudi Arabia and the Gulf Cooperation Council countries. Int J Infect Dis. 2020; 93: 133-138.
- 20. Alibrahim F, AlAlwan A, Al Thiab K, Alawaji A, Alwan B, Taher L, Bosaeed M. Strongyloides and hookworms co-infection in a liver transplant patient. IDCases. 2021; 24:e01060.
- 21. Camargo JF, Simkins J, Anjan S, Guerra G, Vianna R, Salama S, Albright C, Shipman E, Montoya J, Morris MI, Abbo LM. Implementation of a Strongyloides screening strategy in solid organ transplant donors and recipients. Clin Transplant. 2019; 33(4): e13497.
- 22. Gómez-Junyent J, Paredes-Zapata D, de las Parras ER, González-Costello J, Ruiz-Arranz Á, Cañizares R, Saugar JM, Muñoz J. Real-Time Polymerase Chain Reaction in Stool Detects Transmission of Strongyloides stercoralis from an Infected Donor to Solid Organ Transplant Recipients. Am J Trop Med Hyg. 2016; 94(4): 897-899.