Pain catastrophizing, depression, and anxiety in fibromyalgia patients

Year 2023, Volume: 40 Issue: 3, 466 - 471, 30.09.2023

Habibe İnci , Fatih İnci

Abstract

Psychiatric findings may be seen in Fibromyalgia (FM) patients. We aimed to evaluate the relationship between anxiety, depression, and pain catastrophizing in FM patients and normal individuals. The study group consisted of FM patients and a healthy control group. Socio-demographic data form, Beck Depression Inventory (BDI), Beck Anxiety Inventory (BAI), Visual Analogue Scale (VAS), Fibromyalgia Impact Questionnaire (FIQ), and Pain Catastrophizing Scale (PCS) were administered to the participants. It was evaluated whether there was a statistical difference between the groups in terms of BDI, BAI, PCS, VAS, and FIQ. Of the 178 patients in our study, 85 were FM patients and 93 were control groups. The BDI, BAI, PCS, PCSH (PCS Helplessness), PCSM (PCS Magnification), and PCSR (PCS Rumination) were found to be higher in FM patients compared to the control group. The FM patients were found to have moderate depression according to the BDI score (18.7±10.6) and moderate anxiety according to the BAI score (16.5±9.9). There was a positive correlation between BDI and BAI, FIQ and VAS, PCS and BDI, BAI and FIQ, and BAI and FIQ. It was found that the FM patients had “moderate” depression and anxiety, and their level of pain catastrophizing increased with the increase in depression and anxiety severity.

Keywords

Fibromyalgia, Depression, Anxiety, Pain Catastrophizing

Project Number

yok

References

• 1. Mist SD, Jones KD. Randomized Controlled Trial of Acupuncture for Women with Fibromyalgia: Group Acupuncture with Traditional Chinese Medicine Diagnosis-Based Point Selection. Pain Med. 2018 Sep 1;19(9):1862-1871.
• 2. Galvez-Sánchez CM, Reyes Del Paso GA. Diagnostic Criteria for Fibromyalgia: Critical Review and Future Perspectives. J Clin Med. 2020 Apr 23;9(4):1219.
• 3. Ribeiro VGC, Mendonça VA, Souza ALC, Fonseca SF, Camargos ACR, Lage VKS, et al. Inflammatory biomarkers responses after acute whole body vibration in fibromyalgia. Braz J Med Biol Res. 2018 Mar 1;51(4):e6775.
• 4. Karatay S, Okur SC, Uzkeser H, Yildirim K, Akcay F. Effects of Acupuncture Treatment on Fibromyalgia Symptoms, Serotonin, and Substance P Levels: A Randomized Sham and Placebo-Controlled Clinical Trial. Pain Med. 2018 Mar 1;19(3):615-628.
• 5. Croft PR, Papageorgiou AC, Ferry S, Thomas E, Jayson MI, Silman AJ. Psychologic distress and low back pain. Evidence from a prospective study in the general population. Spine (Phila Pa 1976). 1995 Dec 15;20(24):2731-7.
• 6. Demyttenaere K, Bonnewyn A, Bruffaerts R, Brugha T, De Graaf R, Alonso J. Comorbid painful physical symptoms and depression: prevalence, work loss, and help seeking. J Affect Disord. 2006 Jun;92(2-3):185-93.
• 7. Buenaver LF, Edwards RR, Smith MT, Gramling SE, Haythornthwaite JA. Catastrophizing and pain-coping in young adults: associations with depressive symptoms and headache pain. J Pain. 2008 Apr;9(4):311-9.
• 8. Sullivan MJ, Bishop SR, Pivik J. The pain catastrophizing scale: development and validation. Psychological assessment. 1995;7(4):524.
• 9. de Boer MJ, Struys MM, Versteegen GJ. Pain-related catastrophizing in pain patients and people with pain in the general population. Eur J Pain. 2012 Aug;16(7):1044-52.
• 10. Gracely RH, Geisser ME, Giesecke T, Grant MA, Petzke F, Williams DA, et al. Pain catastrophizing and neural responses to pain among persons with fibromyalgia. Brain. 2004 Apr;127(Pt 4):835-43.
• 11. Alev A, Mihriban A, Bilge E, Ayça E, Merve K, Şeyma C, et al. Effects of whole body vibration therapy in pain, function and depression of the patients with fibromyalgia. Complement Ther Clin Pract. 2017 Aug;28:200-203.
• 12. Beck AT, Ward CH, Mendelson M, Mock J, Erbaugh J. An inventory for measuring depression. Arch Gen Psychiatry. 1961 Jun;4:561-71.
• 13. Hisli NJJP. Beck depresyon envanterinin universite ogrencileri icin gecerliligi, guvenilirligi. (A reliability and validity study of Beck Depression Inventory in a university student sample). J Psychol, 1989;7:3-13.
• 14. Yavuz KF, Yavuz N, Ulusoy S, Alniak I, Günes HNG. Gerilim ve Migren Tipi Bas Agrilarina Eslik Eden Islevsel Olmayan Bilissel Içerikler ve Tutumlar/Maladaptive cognitive content and attitudes accompanying tension type headache and migraine. Dusunen Adam. 2013;26(1):12.
• 15. Szkutnik-Fiedler D, Grzeskowiak E. Coexistence of chronic pain and depression: A short review with a focus on the anti-depressant effect of tramadol and buprenorphine. Neuropsychiatry. 2018;8(1):80-8.
• 16. Holmes A, Christelis N, Arnold C. Depression and chronic pain. Med J Aust. 2013 Sep 16;199(S6):S17-20.
• 17. Borg C, Padovan C, Thomas-Antérion C, Chanial C, Sanchez A, Godot M, et al. Pain-related mood influences pain perception differently in fibromyalgia and multiple sclerosis. J Pain Res. 2014 Jan 22;7:81-7.
• 18. Thieme K, Turk DC, Flor H. Comorbid depression and anxiety in fibromyalgia syndrome: relationship to somatic and psychosocial variables. Psychosom Med. 2004 Nov-Dec;66(6):837-44.
• 19. Güven AZ, Kul Panza E, Gündüz OH. Depression and psychosocial factors in Turkish women with fibromyalgia syndrome. Eura Medicophys. 2005 Dec;41(4):309-13.
• 20. Turkyilmaz AK, Kurt EE, Karkucak M, Capkin E. Sociodemographic characteristics, clinical signs and quality of life in patients with fibromyalgia. Eurasian J Med. 2012 Aug;44(2):88-93.
• 21. Kurtze N, Gundersen KT, Svebak S. The role of anxiety and depression in fatigue and patterns of pain among subgroups of fibromyalgia patients. Br J Med Psychol. 1998 Jun;71 ( Pt 2):185-94.
• 22. 2Grothe DR, Scheckner B, Albano D. Treatment of pain syndromes with venlafaxine. Pharmacotherapy. 2004 May;24(5):621-9.
• 23. Salazar A, Dueñas M, Mico JA, Ojeda B, Agüera-Ortiz L, Cervilla JA, et al. Undiagnosed mood disorders and sleep disturbances in primary care patients with chronic musculoskeletal pain. Pain Med. 2013 Sep;14(9):1416-25.
• 24. Burns JW, Johnson BJ, Mahoney N, Devine J, Pawl R. Cognitive and physical capacity process variables predict long-term outcome after treatment of chronic pain. J Consult Clin Psychol. 1998 Apr;66(2):434-9.
• 25. Hudson JI, Mangweth B, Pope HG Jr, De Col C, Hausmann A, Gutweniger S, et al. Family study of affective spectrum disorder. Arch Gen Psychiatry. 2003 Feb;60(2):170-7.
• 26. Taylor AMW, Becker S, Schweinhardt P, Cahill C. Mesolimbic dopamine signaling in acute and chronic pain: implications for motivation, analgesia, and addiction. Pain. 2016 Jun;157(6):1194-1198.
• 27. Haase J, Brown E. Integrating the monoamine, neurotrophin and cytokine hypotheses of depression--a central role for the serotonin transporter? Pharmacol Ther. 2015 Mar;147:1-11.
• 28. Häuser W, Urrútia G, Tort S, Uçeyler N, Walitt B. Serotonin and noradrenaline reuptake inhibitors (SNRIs) for fibromyalgia syndrome. Cochrane Database Syst Rev. 2013 Jan 31;(1):CD010292.
• 29. Hubbard CS, Khan SA, Keaser ML, Mathur VA, Goyal M, Seminowicz DA. Altered Brain Structure and Function Correlate with Disease Severity and Pain Catastrophizing in Migraine Patients. eNeuro. 2014 Dec 30;1(1):e20.14.
• 30. Sheng J, Liu S, Wang Y, Cui R, Zhang X. The Link between Depression and Chronic Pain: Neural Mechanisms in the Brain. Neural Plast. 2017;2017:9724371.
• 31. Jesus DXGd, Pacheco CdR, Rezende RM. The use of Pilates for pain control in patients with fibromyalgia. Fisioterapia em Movimento. 2022;35.
• 32. Gürbüz C, Yilmaz H, Odabaşi FÖ, Göksu H, Akkurt HE. Type and Frequency of Primary Headache in Female Patients with Fibromyalgia Syndrome. Journal of Physical Medicine & Rehabilitation Sciences/Fiziksel Tıp ve Rehabilitasyon Bilimleri Dergisi. 2021;24(2).