Case Report
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Endoscopic band ligation of a proximal duodenal varix; Case report (with video)

Year 2024, Volume: 41 Issue: 2, 425 - 428, 19.05.2024

Abstract

Duodenal varices are a rare consequence of portal hypertension, which constitute 17% of ectopic varices, if these varices bleed, the mortality is around 40%. Medical therapies, including vasopressin, have limited success in controlling active duodenal variceal bleeding. We present a case of a 52 y-o woman who presented with hematochezia and deep anemia requiring multiple transfusions. She has a history of being diagnosed with cirrhosis, FMF, hemochromatosis and factor V Leiden mutation with multiple deep vein thrombosis. The abdomen computer tomography (CT) revealed active bleeding vat the proximal duodenum. She underwent emergent esophagogastroduodenoscopy, which showed actively pulsatile bleeding duodenal varices. Endoscopic hemostasis was achieved successfully with variceal band ligation. Endoscopic band ligation is an effective intervention for actively bleeding duodenal varices, especially for those located in the proximal duodenum, which were more accessible endoscopically than the distal ones.

References

  • GBD 2017 Causes of Death Collaborators. Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018 Nov 10;392(10159):1736-1788. doi: 10.1016/S0140-6736(18)32203-7.
  • GBD 2017 Cirrhosis Collaborators. The global, regional, and national burden of cirrhosis by cause in 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet Gastroenterol Hepatol. 2020 Mar;5(3):245-266. doi: 10.1016/S2468-1253(19)30349-8.
  • Lesmana CRA, Raharjo M, Gani RA. Managing liver cirrhotic complications: Overview of esophageal and gastric varices. Clin Mol Hepatol. 2020 Oct;26(4):444-460. doi: 10.3350/cmh.2020.0022.
  • de Franchis R, Bosch J, Garcia-Tsao G, Reiberger T, Ripoll C; Baveno VII Faculty. Baveno VII - Renewing consensus in portal hypertension. J Hepatol. 2022 Apr;76(4):959-974. doi: 10.1016/j.jhep.2021.12.022.
  • Norton ID, Andrews JC, Kamath PS. Management of ectopic varices. Hepatology. 1998 Oct;28(4):1154-8. doi: 10.1002/hep.510280434.
  • House T, Webb P, Baarson C. Massive Hemorrhage from Ectopic Duodenal Varices: Importance of a Multidisciplinary Approach. Case Rep Gastroenterol. 2017 Jan 27;11(1):36-41. doi: 10.1159/000455184.
  • Kinkhabwala M, Mousavi A, Iyer S, Adamsons R. Bleeding ileal varicosity demonstrated by transhepatic portography. AJR Am J Roentgenol. 1977 Sep;129(3):514-6. doi: 10.2214/ajr.129.3.514.
  • Sato T. Treatment of ectopic varices with portal hypertension. World J Hepatol. 2015 Jun 28;7(12):1601-5. doi: 10.4254/wjh.v7.i12.1601.
  • Goral V, Yılmaz N. Current Approaches to the Treatment of Gastric Varices: Glue, Coil Application, TIPS, and BRTO. Medicina (Kaunas). 2019 Jul 3;55(7):335. doi: 10.3390/medicina55070335.
  • Copelan A, Chehab M, Dixit P, Cappell MS. Safety and efficacy of angiographic occlusion of duodenal varices as an alternative to TIPS: review of 32 cases. Ann Hepatol. 2015 May-Jun;14(3):369-79.
  • Gunnerson AC, Diehl DL, Nguyen VN, Shellenberger MJ, Blansfield J. Endoscopic duodenal variceal ligation: a series of 4 cases and review of the literature (with video). Gastrointest Endosc. 2012 Oct;76(4):900-4. doi: 10.1016/j.gie.2012.05.020.
  • Khouqeer F, Morrow C, Jordan P. Duodenal varices as a cause of massive upper gastrointestinal bleeding. Surgery. 1987 Sep;102(3):548-52. PMID: 3498234.
  • Malik A, Junglee N, Khan A, Sutton J, Gasem J, Ahmed W. Duodenal varices successfully treated with cyanoacrylate injection therapy. BMJ Case Rep. 2011 May 24;2011:bcr0220113913. doi: 10.1136/bcr.02.2011.3913.
  • Attila T, Kolbeck KJ, Bland ZM, Wang A, Rodriguez SA. Duodenal variceal bleeding successfully treated with transjugular intrahepatic portosystemic shunt: a case report and review of the literature. Turk J Gastroenterol. 2008 Dec;19(4):284-90.
  • Kinzel J, Pichetshote N, Dredar S, Aslanian H, Nagar A. Bleeding from a duodenal varix: a unique case of variceal hemostasis achieved using EUS-guided placement of an embolization coil and cyanoacrylate. J Clin Gastroenterol. 2014 Apr;48(4):362-4. doi: 10.1097/MCG.0000000000000004.
  • Yipeng W, Cong L, Sizhe W, Chenkai H, Anjiang W, Xuan Z. Effectiveness and safety of endoscopic treatment for duodenal variceal bleeding: a systematic review. Eur J Gastroenterol Hepatol. 2021 Apr 1;33(4):461-469. doi: 10.1097/MEG.0000000000001819.
  • Akazawa Y, Murata I, Yamao T, Yamakawa M, Kawano Y, Nomura N, et al. Successful management of bleeding duodenal varices by endoscopic variceal ligation and balloon-occluded retrograde transvenous obliteration. Gastrointest Endosc. 2003 Nov;58(5):794-7. doi: 10.1016/s0016-5107(03)02008-x.
  • Schmeltzer PA, Smith MT. Duodenal variceal bleeding successfully treated with endoscopic banding (with video). Gastrointest Endosc. 2011 Sep;74(3):716-7. doi: 10.1016/j.gie.2010.09.030.
  • Miyakoda K, Takedatsu H, Emori K, Inoue H, Toyonaga A, Mitsuyama K, et al. N-butyl-2-cyanoacrylate (histoacryl) glue in the right atrium after endoscopic injection for a ruptured duodenal varix: complication of histoacryl injection. Dig Endosc. 2012 May;24(3):192. doi: 10.1111/j.1443-1661.2011.01185.x.
  • Al-Hillawi L, Wong T, Tritto G, Berry PA. Pitfalls in histoacryl glue injection therapy for oesophageal, gastric and ectopic varices: A review. World J Gastrointest Surg. 2016 Nov 27;8(11):729-734. doi: 10.4240/wjgs.v8.i11.729.
  • Fujii-Lau LL, Law R, Wong Kee Song LM, Gostout CJ, Kamath PS, Levy MJ. Endoscopic ultrasound (EUS)-guided coil injection therapy of esophagogastric and ectopic varices. Surg Endosc. 2016 Apr;30(4):1396-404. doi: 10.1007/s00464-015-4342-3.
  • Tan NC, Ibrahim S, Tay KH. Successful management of a bleeding duodenal varix by endoscopic banding. Singapore Med J. 2005 Dec;46(12):723-5.
Year 2024, Volume: 41 Issue: 2, 425 - 428, 19.05.2024

Abstract

References

  • GBD 2017 Causes of Death Collaborators. Global, regional, and national age-sex-specific mortality for 282 causes of death in 195 countries and territories, 1980-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet. 2018 Nov 10;392(10159):1736-1788. doi: 10.1016/S0140-6736(18)32203-7.
  • GBD 2017 Cirrhosis Collaborators. The global, regional, and national burden of cirrhosis by cause in 195 countries and territories, 1990-2017: a systematic analysis for the Global Burden of Disease Study 2017. Lancet Gastroenterol Hepatol. 2020 Mar;5(3):245-266. doi: 10.1016/S2468-1253(19)30349-8.
  • Lesmana CRA, Raharjo M, Gani RA. Managing liver cirrhotic complications: Overview of esophageal and gastric varices. Clin Mol Hepatol. 2020 Oct;26(4):444-460. doi: 10.3350/cmh.2020.0022.
  • de Franchis R, Bosch J, Garcia-Tsao G, Reiberger T, Ripoll C; Baveno VII Faculty. Baveno VII - Renewing consensus in portal hypertension. J Hepatol. 2022 Apr;76(4):959-974. doi: 10.1016/j.jhep.2021.12.022.
  • Norton ID, Andrews JC, Kamath PS. Management of ectopic varices. Hepatology. 1998 Oct;28(4):1154-8. doi: 10.1002/hep.510280434.
  • House T, Webb P, Baarson C. Massive Hemorrhage from Ectopic Duodenal Varices: Importance of a Multidisciplinary Approach. Case Rep Gastroenterol. 2017 Jan 27;11(1):36-41. doi: 10.1159/000455184.
  • Kinkhabwala M, Mousavi A, Iyer S, Adamsons R. Bleeding ileal varicosity demonstrated by transhepatic portography. AJR Am J Roentgenol. 1977 Sep;129(3):514-6. doi: 10.2214/ajr.129.3.514.
  • Sato T. Treatment of ectopic varices with portal hypertension. World J Hepatol. 2015 Jun 28;7(12):1601-5. doi: 10.4254/wjh.v7.i12.1601.
  • Goral V, Yılmaz N. Current Approaches to the Treatment of Gastric Varices: Glue, Coil Application, TIPS, and BRTO. Medicina (Kaunas). 2019 Jul 3;55(7):335. doi: 10.3390/medicina55070335.
  • Copelan A, Chehab M, Dixit P, Cappell MS. Safety and efficacy of angiographic occlusion of duodenal varices as an alternative to TIPS: review of 32 cases. Ann Hepatol. 2015 May-Jun;14(3):369-79.
  • Gunnerson AC, Diehl DL, Nguyen VN, Shellenberger MJ, Blansfield J. Endoscopic duodenal variceal ligation: a series of 4 cases and review of the literature (with video). Gastrointest Endosc. 2012 Oct;76(4):900-4. doi: 10.1016/j.gie.2012.05.020.
  • Khouqeer F, Morrow C, Jordan P. Duodenal varices as a cause of massive upper gastrointestinal bleeding. Surgery. 1987 Sep;102(3):548-52. PMID: 3498234.
  • Malik A, Junglee N, Khan A, Sutton J, Gasem J, Ahmed W. Duodenal varices successfully treated with cyanoacrylate injection therapy. BMJ Case Rep. 2011 May 24;2011:bcr0220113913. doi: 10.1136/bcr.02.2011.3913.
  • Attila T, Kolbeck KJ, Bland ZM, Wang A, Rodriguez SA. Duodenal variceal bleeding successfully treated with transjugular intrahepatic portosystemic shunt: a case report and review of the literature. Turk J Gastroenterol. 2008 Dec;19(4):284-90.
  • Kinzel J, Pichetshote N, Dredar S, Aslanian H, Nagar A. Bleeding from a duodenal varix: a unique case of variceal hemostasis achieved using EUS-guided placement of an embolization coil and cyanoacrylate. J Clin Gastroenterol. 2014 Apr;48(4):362-4. doi: 10.1097/MCG.0000000000000004.
  • Yipeng W, Cong L, Sizhe W, Chenkai H, Anjiang W, Xuan Z. Effectiveness and safety of endoscopic treatment for duodenal variceal bleeding: a systematic review. Eur J Gastroenterol Hepatol. 2021 Apr 1;33(4):461-469. doi: 10.1097/MEG.0000000000001819.
  • Akazawa Y, Murata I, Yamao T, Yamakawa M, Kawano Y, Nomura N, et al. Successful management of bleeding duodenal varices by endoscopic variceal ligation and balloon-occluded retrograde transvenous obliteration. Gastrointest Endosc. 2003 Nov;58(5):794-7. doi: 10.1016/s0016-5107(03)02008-x.
  • Schmeltzer PA, Smith MT. Duodenal variceal bleeding successfully treated with endoscopic banding (with video). Gastrointest Endosc. 2011 Sep;74(3):716-7. doi: 10.1016/j.gie.2010.09.030.
  • Miyakoda K, Takedatsu H, Emori K, Inoue H, Toyonaga A, Mitsuyama K, et al. N-butyl-2-cyanoacrylate (histoacryl) glue in the right atrium after endoscopic injection for a ruptured duodenal varix: complication of histoacryl injection. Dig Endosc. 2012 May;24(3):192. doi: 10.1111/j.1443-1661.2011.01185.x.
  • Al-Hillawi L, Wong T, Tritto G, Berry PA. Pitfalls in histoacryl glue injection therapy for oesophageal, gastric and ectopic varices: A review. World J Gastrointest Surg. 2016 Nov 27;8(11):729-734. doi: 10.4240/wjgs.v8.i11.729.
  • Fujii-Lau LL, Law R, Wong Kee Song LM, Gostout CJ, Kamath PS, Levy MJ. Endoscopic ultrasound (EUS)-guided coil injection therapy of esophagogastric and ectopic varices. Surg Endosc. 2016 Apr;30(4):1396-404. doi: 10.1007/s00464-015-4342-3.
  • Tan NC, Ibrahim S, Tay KH. Successful management of a bleeding duodenal varix by endoscopic banding. Singapore Med J. 2005 Dec;46(12):723-5.
There are 22 citations in total.

Details

Primary Language English
Subjects Health Care Administration
Journal Section Case Report
Authors

Omer Kucukdemırcı 0000-0001-7642-2793

Hasan Eruzun 0000-0003-0355-1820

Ufuk Avcıoğlu 0000-0001-6905-4494

Publication Date May 19, 2024
Submission Date May 2, 2023
Acceptance Date March 19, 2024
Published in Issue Year 2024 Volume: 41 Issue: 2

Cite

APA Kucukdemırcı, O., Eruzun, H., & Avcıoğlu, U. (2024). Endoscopic band ligation of a proximal duodenal varix; Case report (with video). Journal of Experimental and Clinical Medicine, 41(2), 425-428.
AMA Kucukdemırcı O, Eruzun H, Avcıoğlu U. Endoscopic band ligation of a proximal duodenal varix; Case report (with video). J. Exp. Clin. Med. May 2024;41(2):425-428.
Chicago Kucukdemırcı, Omer, Hasan Eruzun, and Ufuk Avcıoğlu. “Endoscopic Band Ligation of a Proximal Duodenal Varix; Case Report (with Video)”. Journal of Experimental and Clinical Medicine 41, no. 2 (May 2024): 425-28.
EndNote Kucukdemırcı O, Eruzun H, Avcıoğlu U (May 1, 2024) Endoscopic band ligation of a proximal duodenal varix; Case report (with video). Journal of Experimental and Clinical Medicine 41 2 425–428.
IEEE O. Kucukdemırcı, H. Eruzun, and U. Avcıoğlu, “Endoscopic band ligation of a proximal duodenal varix; Case report (with video)”, J. Exp. Clin. Med., vol. 41, no. 2, pp. 425–428, 2024.
ISNAD Kucukdemırcı, Omer et al. “Endoscopic Band Ligation of a Proximal Duodenal Varix; Case Report (with Video)”. Journal of Experimental and Clinical Medicine 41/2 (May 2024), 425-428.
JAMA Kucukdemırcı O, Eruzun H, Avcıoğlu U. Endoscopic band ligation of a proximal duodenal varix; Case report (with video). J. Exp. Clin. Med. 2024;41:425–428.
MLA Kucukdemırcı, Omer et al. “Endoscopic Band Ligation of a Proximal Duodenal Varix; Case Report (with Video)”. Journal of Experimental and Clinical Medicine, vol. 41, no. 2, 2024, pp. 425-8.
Vancouver Kucukdemırcı O, Eruzun H, Avcıoğlu U. Endoscopic band ligation of a proximal duodenal varix; Case report (with video). J. Exp. Clin. Med. 2024;41(2):425-8.