Ortalama trombosit hacmi periprostetik eklem enfeksiyonunun tanısında faydalı bir parametre midir?

Year 2020, Volume: 12 Issue: 2, 313 - 320, 01.06.2020

Ahmet Onur Akpolat , Demet Pepele Kurdal Mehmet Fatih Aksay

https://doi.org/10.21601/ortadogutipdergisi.772451

Abstract

Giriş: Literatürde Ortalama Trombosit hacminin (OTH) enfeksiyöz ve inflamatuar olaylarda bir tanı belirteci olarak kullanıldığı görülmektedir. Amacımız OTH’nin periprostetik eklem enfeksiyonu tanısında yararlı bir parametre olup olmadığını araştırmaktır.

Araç ve Yöntemler: Çalışmaya 37 (%33,6) periprostetik eklem infeksiyonlu, 38 (%34,6) diz artroplastili ve 35 (%31,8) kontrol grubunu oluşturan 110 hasta dahil edildi. Preoperatif dönem ve kontroller sırasında alınan rutin laboratuvar örneklerinde OTH, trombosit, eritrosit sedimantasyon hızı (ESR) ve C reaktif protein (CRP) değerlerine bakıldı. Sonuçlar grup içi ve gruplar arasında Shapiro-Wilk, One-way ANOVA, Bonferroni, tPearson’s, Chi-square testleri ile istatiksel olarak değerlendirildi. p<0.05 ve p<0.01 değerleri anlamlı kabul edildi.

Bulgular: Preoperatif dönemde grupların trombosit ve OTH değerleri arasında istatiksel fark saptanmadı. Periprostatik eklem enfeksiyonu olan grubun postoperatif OTH düzeyleri hem kontrol hem de TKA grubuna göre anlamlı düşük, trombosit, CRP ve ESR düzeyleri ise anlamlı yüksek saptandı (p<0.05).

Sonuç: OTH periprostetik eklem enfeksiyonu tanısında kullanılabilecek faydalı bir laboratuvar parametresidir.

Keywords

Ortalama Trombosit Hacmi, periprostetik, enfeksiyon, tanı, diz

Is mean platelet volume a helpful parameter in diagnosing periprosthetic joint infection?

Abstract

Introduction: Mean Platelet Volume (MPV) is encountered in the literature as a diagnostic marker used to monitor infectious and inflammatory events. We aimed to investigate whether or not there was a change in platelet and MPV parameters in patients diagnosed with periprosthetic join infection (PJI).

Material and Methods: A total of 110 patients were included in the study, consisting of 37 (33.6%) patients with periprosthetic join infection, 38 (34.6%) patients with total knee arthroplasty (TKA), and 35 (31.8%) control group subjects. During the preoperative period and follow-up, MPV, platelet, erythrocyte sedimentation rate (ESR) and C-reactive protein (CRP) values were assessed from routine laboratory tests. Statistical analyses of values between and within groups were conducted using Shapiro-Wilk test, One-way ANOVA, Bonferroni’s test, Pearson’s test, and Chi-square test. P<0.05 and p<0.01 values were considered statistically significant.

Results: There was no statistically significant difference among the groups according to preoperative platelet and MPV values (p>0.05). Postoperative MPV levels were significantly lower and platelet, ESR and CRP levels were significantly high in the PJI group compared to both the control group and the TKA group (p<0.05).

Conclusion: MPV is a useful laboratory parameter in the diagnosis of periprosthetic joint infection in patients.

Keywords

Mean Platelet Volume, periprostatic, infection, diagnosis, knee

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