Korpus luteum oluşumu sırasında meydana gelen yapısal değişiklikler

Year 2024, Volume: 17 Issue: 2, 285 - 301, 01.04.2024

Murat Serkant Ünal , Semih Tan , Mücahit Seçme

https://doi.org/10.31362/patd.1383988

Abstract

Amaç: Çalışmamız, korpus luteum'un bitişiğindeki yüzey epiteli ve tunika albugineanın yeniden yapılanmasından sonra bu bölgedeki fibroblast benzeri hücrelerin arasında yeni foliküllerin oluşup oluşmadığını araştırmayı amaçlamaktadır. Ayrıca, foliküllerden gelişen yapıları ve ovaryumdaki histolojik değişiklikleri göstermek de bir başka hedefimizdir.
Gereç ve yöntem: Ovulasyondan sonra graaf folikülünden oluşan korpus luteum'un histolojik kesitleri, 12-14 aylık Wistar albino tipi sıçanların ovaryum dokularından alınarak hazırlanmıştır.
Bulgular: Korpus luteum yüksek bir hacime ulaştığında, tunika albugineada bulunan fibroblast benzeri hücrelerin sayısı oldukça düşüktür. Daha sonrasında, tunika albuginea bulunan fibroblast benzeri hücrelerin sayısının hızla arttığı ve bu hücrelerin oluşturduğu kollajen liflerin konsantrik dizilim oluşturdukları gözlemlenmiştir. Ayrıca, korpus luteumun bitişiğindeki yüzey epiteli ve tunika albuginea tabakası arasında primordial ve primer foliküllerin oluştuğu izlenmiştir.
Sonuç: Ovaryumu bir bütün olarak ele almak ve yapıların gelişim süreçlerini incelemek, bu organın dinamiklerini daha iyi anlamamıza yardımcı olabilir.

Keywords

Korpus luteum, ovaryum, tunika albuginea, folikül

Changes in structure during the corpus luteum's formation

Abstract

Purpose: Our study aims to investigate whether new follicles form among fibroblast-like cells in the region after the restructuring of the surface epithelium and tunica albuginea adjacent to the corpus luteum. Additionally, another goal is to demonstrate the structures developed from the follicles and the histological changes in the ovary.
Materials and methods: Histological sections of the corpus luteum, formed from the Graafian follicle after ovulation, were prepared from ovarian tissues of 12-14 months old Wistar albino rats.
Results: When the corpus luteum reaches a high volume, the number of fibroblast-like cells in the tunica albuginea is quite low. Subsequently, it has been observed that the number of fibroblast-like cells in the tunica albuginea rapidly increases, and these cells form concentric arrangements of collagen fibers. Additionally, the formation of primordial and primary follicles between the surface epithelium and the tunica albuginea adjacent to the corpus luteum has been observed.
Conclusion: Examining the ovary as a whole and investigating the developmental processes of structures can assist in gaining a better understanding of the dynamics of this organ.

Keywords

Corpus Luteum, ovary, tunica albuginea, follicles

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