Glutamate, Excitotoxicity and Releated Diseases

Year 2023, Volume: 1 Issue: 1, 32 - 62, 30.04.2023

Ayşenur Budak Savaş , Mehmet Ali Yörük , Cemil Bayram , Selma Sezen

Abstract

Glutamate is an excitatory neurotransmitter that is abundant in many central and peripheral tissues and is essential for cell survival and body homeostasis. Although its existence has been known for many years, research still reveals that excitotoxicity plays a role in the development of new pathological conditions. For this reason, glutamate and glutamate excitotoxicity must be well understood, and glutamate-related circumstances must be clarified.

Keywords

AMPAR, EAAT, Excitotoxicity, Glutamate, Kainate, mGluR, NMDAR

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