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DETERMINATION OF DRUG-RELATED RISK BEHAVIOURS OF PATIENTS USING ORAL ANTICOAGULANTS AND INNOVATIVE SOLUTIONS

Year 2022, Volume: 1 Issue: 1, 1 - 11, 01.12.2023

Abstract

The aim of this study is to gather valuable information about the drug-related risk behaviours of patients to be exposed to use the oral anticoagulants so that we provide necessary solutions founded on the needs of patients. This study was conducted as a prospective, descriptive and cross-sectional study in the cardiology and cardiovascular services of outpatient clinics. The study data related to the patients subjected to use the oral anticoagulants during the 2-month period were collected. There seemed no anticoagulant treatment except for warfarin treatment among the patients participated in the study, where %57.8 (n:59) of participates were over 65 years old. It was determined that most of the patients in the study reported that they have no knowledge about the findings of bleeding, do not know the drug/food interactions and INR values, used missing or overdose the drugs due to the lack of knowledge about oral anticoagulant use. The physicians and nurses play a great role on the education of patients using the oral anticoagulants that take in the medicines with high-risk. Information systems such as mobile phone applications and computer applications can also be used to remind the patients.

References

  • 1.Alay, M., Demir, C., Atmaca, M., Esen, R., & Dilek,İ. (2011). Evaluation of Patients withComplications of Bleeding in Oral AnticoagulantTherapy. Van Medical Journal, 18(1), 9–14.
  • 2.Baysal, E., & Midilli, T. S. (2018). Effects ofstructured patient education on knowledge leveland inr control of patients receiving warfarin:Randomized controlled trial. Pakistan Journal ofMedical Sciences, 34(2), 240–426.https://doi.org/10.12669/pjms.342.14216
  • 3.Bushra, R., Aslam, N., & Yar Khan, A. (2011). Food-drug interactions. Oman Medical Journal, 26(2),77–83. https://doi.org/10.5001/omj.2011.21
  • 4.Dogu, O., & Acaroglu, R. (2016). Evaluation ofMedication Management Safety in Patients UsingOral Anticoagulants. Journal of Anatolia Nursingand Health Sciences, 19(3), 152–158.
  • 5.Fitzmaurice, D. A. (2002). ABC of antithrombotictherapy: Bleeding risks of antithrombotic therapy. BMJ (Clinical Research Ed.), 325(7368), 828–831. https://doi.org/10.1136/bmj.325.7368.828
  • 6.Gupta, D., Tang, F., Masoudi, F. A., Jones, P. G.,Chan, P. S., & Daugherty, S. L. (2018). PractitionerGender and Quality of Care in AmbulatoryCardiology Practices: A Report from the NationalCardiovascular Data Practice Innovation andClinical Excellence (PINNACLE) Registry. Journal ofCardiovascular Nursing, 33(3), 255–260.https://doi.org/10.1097/JCN.0000000000000443
  • 7.Hall, A., Cole-Lewis, H., & Bernhardt, J. M. (2015).Mobile Text Messaging for Health: A SystematicReview of Reviews. Ssrn.https://doi.org/10.1146/annurev-publhealth-031914-122855
  • 8.Hamine, S., Gerth-Guyette, E., Faulx, D., Green, B.B., & Ginsburg, A. S. (2015). Impact of mHealthchronic disease management on treatment adherence and patient outcomes: A systematic review. Journal of Medical Internet Research, 17(2), 1–15. https://doi.org/10.2196/jmir.3951
  • 9.Hirsh J, Dalen J, Anderson DR, Poller L, Bussey H,Ansell J, D. D. (2001). Oral anticoagulants:mechanism of action, clinical effectiveness, andoptimal therapeutic range. Chest, 119, 8S-21S.
  • 10.Hylek, E. M., Evans-Molina, C., Shea, C., Henault,L.E., & Regan, S. (2007). Major hemorrhage andtolerability of warfarin in the first year of therapyamong elderly patients with atrial fibrillation.Circulation, 115(21), 2689–2696.https://doi.org/10.1161/CIRCULATIONAHA.106.653048
  • 11.Jenner, K. M., & Simmons, B. J. (2015). AnEducation Program for Patient Self-Managementof Warfarin. The Permanente Journal, 19(4), 33–38.https://doi.org/10.7812/TPP/14-246
  • 12.Johnson, M. P. (2013). Transitions of care inpatients receiving oral anticoagulants: Generalprinciples, procedures, and impact of new oralanticoagulants. Journal of CardiovascularNursing, 28(1), 54–65.https://doi.org/10.1097/JCN.0b013e31823776e6
  • 13.Kim, J. H., Kim, G. S., Kim, E. J., Park, S., Chung, N.,& Chu, S. H. (2011). Factors affecting medicationadherence and anticoagulation control in Koreanpatients taking warfarin. Journal ofCardiovascular Nursing, 26(6), 466–474.https://doi.org/10.1097/JCN.0b013e31820914e7
  • 14.Korkmaz, F. D., Alcan, A. O., & Karacabay, K.(2015). Do patients with mechanical heart valveshave the appropriate knowledge regardingwarfarin therapy and can they adhere to thecorrect dosage? Turkish Journal of Thoracic andCardiovascular Surgery, 23(1), 58–65.https://doi.org/10.5606/tgkdc.dergisi.2015.10390
  • 15.Nasser, S., Mullan, J., & Bajorek, B. (2012).Challenges of Older Patients’ Knowledge AboutWarfarin Therapy. Journal of Primary Care andCommunity Health, 3(1), 65–74.https://doi.org/10.1177/2150131911416365
  • 16.Oterhals, K., Deaton, C., De Geest, S., Jaarsma, T.,Lenzen, M., Moons, P., Mårtensson, J., Smith, K.,Stewart, S., Strömberg, A., Thompson, D. R., &Norekvål, T. M. (2014). European cardiac nurses’ current practice and knowledge on anticoagulation therapy. European Journal of Cardiovascular Nursing, 13(3), 261–269. https://doi.org/10.1177/1474515113491658
  • 17.Othilia, E., Tang, Y. L., Lai, C. S. M., Lee, K. K. C.,Wong, R. S. M., Cheng, G., & Chan, T. Y. K. (2003).Relationship Between Patients ’ WarfarinKnowledge and Anticoagulation ControlOBJECTIVE : METHODS : Ambulatory Care, 37,34–39.
  • 18.Ozer, E., & Ozdemir, L. (2009). Rational DrugUsage in Elderly and Nurse’s Responsibilities.Health Sciences Faculty Nursing Journal, 42–51.
  • 19.Sevda Mercan, N. E. (2011). Educational Needs ofPatients with Warfarin. Turk Soc Cardiol TurkishJournal of Cardiovascular Nursing, 12–17.https://doi.org/10.5543/khd.2011.003
  • 20.Shaha, M., Wüthrich, E., Stauffer, Y., Herczeg, F.,Fattinger, K., Hirter, K., Papalini, M., & Herrmann,L.(2015). Implementing evidence-based patientand family education on oral anticoagulationtherapy: A community-based participatoryproject. Journal of Clinical Nursing, 24(11–12),1534–1545. https://doi.org/10.1111/jocn.12743
  • 21.Taze Koksal, A., & Avsar, G. (2015). What PatientsTaking Oral Anticoagulants Know And Do AboutAnticoagulant Therapy: Evaluation Of Patients inA Cardiology Service. Balıkesır Health SciencesJournal, 4(3), 137–142.https://doi.org/10.5505/bsbd.2015.61587
  • 22.Tezer, F. İ., Arsava, M., Gökoğlu, A., Karabulut, E.,Ay, H., & Sarıbaş, O. (2008). Risk Assessment OfCoumadin-related Intracranial Hemorrhage ViaMagnetic Resonance Imaging In Patients WithIschemic Stroke. Ankara University MedicalFaculty Journal, 61(1), 13–24.
  • 23.Tugut, N., & Bekar, M. (2008). Relationshipbetween Perceptions of Health Status ofUniversity Students and Healty LifestyleBehaviors. Journal of Ataturk Universty School ofNursing, 11(3), 17–26.
  • 24.Uygungul, E., Ayri, C., Narci, H., Erdoğan, S., Toker,I., Demir, F., & Karaaslan, U. (2014). Determiningrisk factors of bleeding in patients on warfarintreatment. Advances in Hematology, 2014, 1–5.
  • 25.W., Q., M.R., C., J., C., J., S., & K., P. (2007).Warfarin prevalence, indications for use andhaemorrhagic events. Irish Medical Journal,100(3).http://www.embase.com/search/results?subaction=viewrecord&from=export&id=L46629936%5Cnhttp://imj.ie//Issue_detail.aspx?issueid=+&pid=1860&type=Papers%5Cnhttp://sfx.aub.aau.dk/sfxaub?sid=EMBASE&issn=03323102&id=doi:&atitle=Warfarin+prevalence%2C+indication
  • 26.Wallvik, J., Själander, A., Johansson, L., Bjuhr, Ö.,& Jansson, J. H. (2007). Bleeding complications during warfarin treatment in primary healthcare centres compared with anticoagulation clinics. Scandinavian Journal of Primary Health Care, 25(2), 123–128. https://doi.org/10.1080/02813430601183108
  • 27.Yucel, T., Guclu, S., Atalay, I., & Serin, E. (2001). Acase of Upper Gastrointestinal SystemObstruction by Duedenal Intramural Hematomadue to Using Oral Anticoagulant Drug. TurkishJournal Of Trauma, 7, 210–212.

ORAL ANTİKOAGÜLAN KULLANAN HASTALARIN RİSKLİ DAVRANIŞLARININ BELİRLENMESİ VE YENİLİKÇİ ÇÖZÜMLER

Year 2022, Volume: 1 Issue: 1, 1 - 11, 01.12.2023

Abstract

Çalışmanın amacı, oral antikoagülan kullanan hastaların ilaç kullanımıyla ilgili riskli davranışlarını belirlemek ve böylelikle hastaların ihtiyaçlarına yönelik gerekli çözüm önerilerinde bulunabilmektir. Bu çalışma prospektif, tanımlayıcı ve kesitsel olarak kardiyoloji ile kalp damar cerrahi polikliniklerinde gerçekleştirildi. Çalışmanın verilerinin toplandığı 2 aylık sürede polikliniğe başvuran oral antikoagülan kullanan hastalardan çalışmaya katılmayı kabul edenlerden veriler toplandı. Çalışmaya katılan hastaların varfarin tedavisi dışında antikoagülan tedai kullanımı görülmemiştir ve katılımcıların %57,8’i (n:59) 65 yaşın üzerindedir. Çalışmaya katılan hastaların çoğunun tedaviye bağlı kanama, ilaç-gıda etkileşimleri ve INR değerlerini bilmedikleri, oral antikoagülan hakkında bilgi eksikliği nedeniyle ilaçları eksik veya aşırı doz kullandıkları belirlenmiştir. Doktorlar ve hemşireler, yüksek riskli ilaç grubundan olan oral antikoagülanları kullanan hastaların eğitiminde önemli rol oynamaktadırlar. Cep telefonu uygulamaları hastaların ilaç alım saatlerini hatırlatmak için kullanılabilir.

References

  • 1.Alay, M., Demir, C., Atmaca, M., Esen, R., & Dilek,İ. (2011). Evaluation of Patients withComplications of Bleeding in Oral AnticoagulantTherapy. Van Medical Journal, 18(1), 9–14.
  • 2.Baysal, E., & Midilli, T. S. (2018). Effects ofstructured patient education on knowledge leveland inr control of patients receiving warfarin:Randomized controlled trial. Pakistan Journal ofMedical Sciences, 34(2), 240–426.https://doi.org/10.12669/pjms.342.14216
  • 3.Bushra, R., Aslam, N., & Yar Khan, A. (2011). Food-drug interactions. Oman Medical Journal, 26(2),77–83. https://doi.org/10.5001/omj.2011.21
  • 4.Dogu, O., & Acaroglu, R. (2016). Evaluation ofMedication Management Safety in Patients UsingOral Anticoagulants. Journal of Anatolia Nursingand Health Sciences, 19(3), 152–158.
  • 5.Fitzmaurice, D. A. (2002). ABC of antithrombotictherapy: Bleeding risks of antithrombotic therapy. BMJ (Clinical Research Ed.), 325(7368), 828–831. https://doi.org/10.1136/bmj.325.7368.828
  • 6.Gupta, D., Tang, F., Masoudi, F. A., Jones, P. G.,Chan, P. S., & Daugherty, S. L. (2018). PractitionerGender and Quality of Care in AmbulatoryCardiology Practices: A Report from the NationalCardiovascular Data Practice Innovation andClinical Excellence (PINNACLE) Registry. Journal ofCardiovascular Nursing, 33(3), 255–260.https://doi.org/10.1097/JCN.0000000000000443
  • 7.Hall, A., Cole-Lewis, H., & Bernhardt, J. M. (2015).Mobile Text Messaging for Health: A SystematicReview of Reviews. Ssrn.https://doi.org/10.1146/annurev-publhealth-031914-122855
  • 8.Hamine, S., Gerth-Guyette, E., Faulx, D., Green, B.B., & Ginsburg, A. S. (2015). Impact of mHealthchronic disease management on treatment adherence and patient outcomes: A systematic review. Journal of Medical Internet Research, 17(2), 1–15. https://doi.org/10.2196/jmir.3951
  • 9.Hirsh J, Dalen J, Anderson DR, Poller L, Bussey H,Ansell J, D. D. (2001). Oral anticoagulants:mechanism of action, clinical effectiveness, andoptimal therapeutic range. Chest, 119, 8S-21S.
  • 10.Hylek, E. M., Evans-Molina, C., Shea, C., Henault,L.E., & Regan, S. (2007). Major hemorrhage andtolerability of warfarin in the first year of therapyamong elderly patients with atrial fibrillation.Circulation, 115(21), 2689–2696.https://doi.org/10.1161/CIRCULATIONAHA.106.653048
  • 11.Jenner, K. M., & Simmons, B. J. (2015). AnEducation Program for Patient Self-Managementof Warfarin. The Permanente Journal, 19(4), 33–38.https://doi.org/10.7812/TPP/14-246
  • 12.Johnson, M. P. (2013). Transitions of care inpatients receiving oral anticoagulants: Generalprinciples, procedures, and impact of new oralanticoagulants. Journal of CardiovascularNursing, 28(1), 54–65.https://doi.org/10.1097/JCN.0b013e31823776e6
  • 13.Kim, J. H., Kim, G. S., Kim, E. J., Park, S., Chung, N.,& Chu, S. H. (2011). Factors affecting medicationadherence and anticoagulation control in Koreanpatients taking warfarin. Journal ofCardiovascular Nursing, 26(6), 466–474.https://doi.org/10.1097/JCN.0b013e31820914e7
  • 14.Korkmaz, F. D., Alcan, A. O., & Karacabay, K.(2015). Do patients with mechanical heart valveshave the appropriate knowledge regardingwarfarin therapy and can they adhere to thecorrect dosage? Turkish Journal of Thoracic andCardiovascular Surgery, 23(1), 58–65.https://doi.org/10.5606/tgkdc.dergisi.2015.10390
  • 15.Nasser, S., Mullan, J., & Bajorek, B. (2012).Challenges of Older Patients’ Knowledge AboutWarfarin Therapy. Journal of Primary Care andCommunity Health, 3(1), 65–74.https://doi.org/10.1177/2150131911416365
  • 16.Oterhals, K., Deaton, C., De Geest, S., Jaarsma, T.,Lenzen, M., Moons, P., Mårtensson, J., Smith, K.,Stewart, S., Strömberg, A., Thompson, D. R., &Norekvål, T. M. (2014). European cardiac nurses’ current practice and knowledge on anticoagulation therapy. European Journal of Cardiovascular Nursing, 13(3), 261–269. https://doi.org/10.1177/1474515113491658
  • 17.Othilia, E., Tang, Y. L., Lai, C. S. M., Lee, K. K. C.,Wong, R. S. M., Cheng, G., & Chan, T. Y. K. (2003).Relationship Between Patients ’ WarfarinKnowledge and Anticoagulation ControlOBJECTIVE : METHODS : Ambulatory Care, 37,34–39.
  • 18.Ozer, E., & Ozdemir, L. (2009). Rational DrugUsage in Elderly and Nurse’s Responsibilities.Health Sciences Faculty Nursing Journal, 42–51.
  • 19.Sevda Mercan, N. E. (2011). Educational Needs ofPatients with Warfarin. Turk Soc Cardiol TurkishJournal of Cardiovascular Nursing, 12–17.https://doi.org/10.5543/khd.2011.003
  • 20.Shaha, M., Wüthrich, E., Stauffer, Y., Herczeg, F.,Fattinger, K., Hirter, K., Papalini, M., & Herrmann,L.(2015). Implementing evidence-based patientand family education on oral anticoagulationtherapy: A community-based participatoryproject. Journal of Clinical Nursing, 24(11–12),1534–1545. https://doi.org/10.1111/jocn.12743
  • 21.Taze Koksal, A., & Avsar, G. (2015). What PatientsTaking Oral Anticoagulants Know And Do AboutAnticoagulant Therapy: Evaluation Of Patients inA Cardiology Service. Balıkesır Health SciencesJournal, 4(3), 137–142.https://doi.org/10.5505/bsbd.2015.61587
  • 22.Tezer, F. İ., Arsava, M., Gökoğlu, A., Karabulut, E.,Ay, H., & Sarıbaş, O. (2008). Risk Assessment OfCoumadin-related Intracranial Hemorrhage ViaMagnetic Resonance Imaging In Patients WithIschemic Stroke. Ankara University MedicalFaculty Journal, 61(1), 13–24.
  • 23.Tugut, N., & Bekar, M. (2008). Relationshipbetween Perceptions of Health Status ofUniversity Students and Healty LifestyleBehaviors. Journal of Ataturk Universty School ofNursing, 11(3), 17–26.
  • 24.Uygungul, E., Ayri, C., Narci, H., Erdoğan, S., Toker,I., Demir, F., & Karaaslan, U. (2014). Determiningrisk factors of bleeding in patients on warfarintreatment. Advances in Hematology, 2014, 1–5.
  • 25.W., Q., M.R., C., J., C., J., S., & K., P. (2007).Warfarin prevalence, indications for use andhaemorrhagic events. Irish Medical Journal,100(3).http://www.embase.com/search/results?subaction=viewrecord&from=export&id=L46629936%5Cnhttp://imj.ie//Issue_detail.aspx?issueid=+&pid=1860&type=Papers%5Cnhttp://sfx.aub.aau.dk/sfxaub?sid=EMBASE&issn=03323102&id=doi:&atitle=Warfarin+prevalence%2C+indication
  • 26.Wallvik, J., Själander, A., Johansson, L., Bjuhr, Ö.,& Jansson, J. H. (2007). Bleeding complications during warfarin treatment in primary healthcare centres compared with anticoagulation clinics. Scandinavian Journal of Primary Health Care, 25(2), 123–128. https://doi.org/10.1080/02813430601183108
  • 27.Yucel, T., Guclu, S., Atalay, I., & Serin, E. (2001). Acase of Upper Gastrointestinal SystemObstruction by Duedenal Intramural Hematomadue to Using Oral Anticoagulant Drug. TurkishJournal Of Trauma, 7, 210–212.
There are 27 citations in total.

Details

Primary Language English
Subjects Surgical Diseases Nursing​​
Journal Section Research Articles
Authors

Arzu İlçe 0000-0001-8428-9865

Ümmühan Yiğit 0000-0001-6791-2299

Ganime Esra Soysal 0000-0002-8291-4310

Publication Date December 1, 2023
Published in Issue Year 2022 Volume: 1 Issue: 1

Cite

APA İlçe, A., Yiğit, Ü., & Soysal, G. E. (2023). DETERMINATION OF DRUG-RELATED RISK BEHAVIOURS OF PATIENTS USING ORAL ANTICOAGULANTS AND INNOVATIVE SOLUTIONS. Sağlık Bakım Ve Rehabilitasyon Dergisi, 1(1), 1-11.