EVALUATION OF PHARMACY EMPLOYEES’ USAGE OF HERBAL PRODUCTS AND KNOWLEDGE ABOUT FOOD–DRUG INTERACTIONS

Year 2024, Volume: 7 Issue: 2, 124 - 131, 04.06.2024

Yasemin Ertaş Öztürk , Onur Yıldıran , Beyza Baycan , Semiha Kadıoğlu

https://doi.org/10.26650/JARHS2024-1341284

Abstract

Objective: This study was conducted to determine and compare herbal product use, attitudes toward herbal products, and the knowledge about food–drug interactions of pharmacy employees.

Materials and Methods: This descriptive cross-sectional study included 132 pharmacy employees, comprising 67 pharmacists, 40 pharmacy technicians, and 25 pharmacy foremen. Demographic characteristics of the participants, herbal product use and attitudes toward herbal products, questions concerning food–drug interactions, and the Food–Drug Interaction Knowledge Level Scale were evaluated. Data were collected through a web-based questionnaire and analyzed using appropriate statistical methods.

Results: Pharmacists used herbal products (p=0.008) and counseled more (p<0.001) than pharmacy technicians/foremen. Most pharmacy employees received questions from patients regarding herbal products. A total of 73.8% of pharmacy technicians/foremen believed that herbal products exert fewer side effects than conventional drugs, and 91.0% of pharmacists believed that herbal products are not regulated and that there is an interaction between conventional drugs and herbal products. The mean Food–Drug Interaction Knowledge Level Scale score of pharmacists was 13.4±3.96, whereas that of pharmacy technicians/ foremen was 7.9±5.46 (p<0.001). Good or very good knowledge about food–drug interactions was found among 79.1% of pharmacists and 33.8% of pharmacy technicians/foremen. Profession (pharmacist vs pharmacy technician/foreman) and having additional education on herbal products significantly affected the scale scores (p<0.001 and p=0.019, respectively).

Conclusion: Pharmacy employees are an important health group who provide counseling on herbal product use and food–drug interactions. Pharmacists’ knowledge about food–drug interactions was higher than that of pharmacy technicians/foremen. Therefore, lifelong learning should be a part of the lives of these professional groups as in every profession.

Keywords

Alternative Medicine, complementary medicine, food–druginteraction, herbal medicine use

Supporting Institution

Bulunmamaktadır.

Project Number

-

Thanks

Authors would like to thank to Dyt. Hatice ÇİMEN for her help on data collection. This study has presented as oral presentation on December 24-25, 2022 at 11th International Medicine and Health Sciences Researches Congress.

ECZANE ÇALIŞANLARININ BİTKİSEL ÜRÜN KULLANIMININ VE BESİN–İLAÇ ETKİLEŞİMLERİ HAKKINDAKİ BİLGİLERİNİN DEĞERLENDİRİLMESİ

Abstract

Amaç: Bu çalışma ile eczane çalışanlarının bitkisel ürün kullanımı, bitkisel ürünlerle ilgili tutumları ve besin-ilaç etkileşimleri hakkındaki bilgilerinin belirlenerek karşılaştırılması amaçlanmıştır.

Gereç ve Yöntem: Çalışma tanımlayıcı tipte kesitsel bir çalışmadır. Çalışmaya 67 eczacı, 40 eczane teknikeri ve 25 eczane kalfası olmak üzere toplam 132 eczane çalışanı katılmıştır. Çalışmanın verileri bireylerin demografik özellikleri, bitkisel ürün kullanımı ve bitkisel ürünler hakkındaki tutumları, besin-ilaç etkileşimine dair sorular ve Besin-İlaç Etkileşimi Bilgi Düzeyini Saptamaya Yönelik Ölçek’i içeren sorulardan oluşmuştur. Veriler web tabanlı bir anket aracılığıyla toplanmış ve uygun istatistiksel yöntemler kullanılarak değerlendirilmiştir.

Bulgular: Eczacıların bitkisel ürünleri eczane teknikerleri/kalfalarına göre daha fazla kullandığı (p=0,008) ve daha fazla danışmanlık yaptığı (p<0,001) belirlenmiştir. Çoğu eczane çalışanı bitkisel ürünler hakkında hastalardan soru almaktadır. Eczane teknikerleri/kalfalarının %73,8’i bitkisel ürünlerin geleneksel ilaçlara göre daha az yan etkisi olduğunu, eczacıların %91,0’i ise bitkisel ürünlerin denetlenmediğini ve geleneksel ilaçlarla bitkisel ürünler arasında etkileşim olduğunu düşünmektedir. Ölçek sonuçlarına göre eczacıların ortalama ölçek puanları 13,4±3,96 iken eczane teknikerleri ve kalfalarının ortalama ölçek puanları 7,9±5,46’dır (p<0,001). Eczacıların %79,1’i eczacı teknikeri/kalfalarının ise %33,8’i iyi ve çok iyi düzeyde besin-ilaç etkileşimi bilgisine sahiptir. Meslek grubunun (eczacı ve eczane teknikeri/ kalfası) ve bitkisel ürünler hakkında ek eğitim almanın ölçek puanlarını anlamlı olarak etkilediği tespit edilmiştir (p<0,001 ve p=0,019).

Sonuç: Eczane çalışanları bitkisel ürün kullanımı ve besin-ilaç etkileşimi konusunda danışmanlık yapan önemli bir sağlık grubudur. Eczacıların besin-ilaç etkileşimi bilgisi eczacı teknikeri/kalfasından yüksektir. Bu nedenle yaşam boyu öğrenme her meslekte olduğu gibi bu meslek gruplarında da hayatın bir parçası olmalıdır.

Keywords

Alternatif Tıp, besin ilaç etkileşimi, bitkisel ilaç kullanımı, tamamlayıcı tıp

Project Number

-

References

• Kemppainen LM, Kemppainen TT, Reippainen JA, Salmenniemi ST, Vuolanto PH. Use of complementary and alternative medicine in Europe: health-related and sociodemographic determinants. Scand J Public Health 2018;46(4):448-55. google scholar
• Molassiotis A, Fernandez-Ortega P, Pud D, Ozden G, Scott JA, Panteli V, et al. Use of complementary and alternative medicine in cancer patients: a European survey. Ann Oncol 2005;16(4):655-63. google scholar
• Kav S, Hanoğlu Z, Algier L. Use of complementary and alternative medicine by cancer patients in Turkey: a literature review. UHOD 2008;18(1):32-8. google scholar
• Kes D, Gökdoğan F, Tuna D. Use of complementary and alternative medicine by hypertensive patients: a literature review. Turk J Card Nur 2016;7(12):40-55. google scholar
• Çetin O.The use of complementary and alternative medicine in Eskisehir. Sosyoekonomi 2007;6(6):90-106. google scholar
• Smith N, Shin DB, Brauer JA, Mao J, Gelfand JM. Use of complementary and alternative medicine among adults with skin disease: results from a national survey. J Am Acad Dermatol 2009;60(3):419-25. google scholar
• Eardley S, Bishop FL, Prescott P, Cardini F, Brinkhaus B, Santos-Rey K, et al. A systematic literature review of complementary and alternative medicine prevalence in EU. Forschende Komplementmed 2012;19(2):18-28. google scholar
• Orhan MF, Elmas B, Altındiş S, Karagöz R, Altındiş M. Aile hekimi ve pediatristlerin geleneksel ve tamamlayıcı tıbba (GETAT) bakışı. J Biotechnol and Strategic Health Res 2019;3(Özel Sayı):161-7. google scholar
• Onbaşlı D, Çelik Yuvalı G, Ceylan A, Dal A. Herbal medicines found in pharmacies in Turkey. ERÜ Sağlık Bilim Fakültesi Derg 2019;6(1):18-31. google scholar
• Süzgeç-Selçuk S, Eyisan S. Herbal medicines availabile in pharmacies in Turkey. Marmara Pharm J 2012;16(3):164-80. google scholar
• Chan LN. Drug-nutrient interactions. J Parenter Enter Nutr 2013;37(4):450-9. google scholar
• Bayraktar Ekincioğlu A, Demirkan K. Nutrient and drug interactions. Beslenme ve Diyet Derg 2014;42(2):154-9. google scholar
• Genser D. Food and drug interaction: consequences for the nutrition/health status. Ann Nutr Metab 2008;52:29-32. google scholar
• Nazer LH, Tuffaha H. Health care and pharmacy practice in Jordan. Can J Hosp Pharm 2017;70(2):150-5. google scholar
• Atavwoda A, Gabriel A. Assessment of pharmacists knowledge, attitude and practices regarding herbal drug information services. J Basic Clin Pharm 2012;3(3):317-22. google scholar
• İstanbulluoğlu S, Celiker A. The role of pharmacist in prevention of drug-herbal product interactions. FABAD J Pharm Sci 2018;43(3):201-16. google scholar
• Yükseköğretim Kurumu. Ulusal çekirdek eğitimi programları: Mezuniyet Öncesi Eczacılık Eğitimi - Ulusal Çekirdek Eğitim Programı 2019 (cited 2023 December 11). https://www.yok.gov. tr/kurumsal/idari-birimler/egitim-ogretim-dairesi/ulusal-cekirdek-egitimi-programlari google scholar
• Karagöz MF, Gezmen Karadağ M, Yıldıran H, Akçil Ok M. Developing a food and drug interaction knowledge scale for health care professionals: a validity and reliability study. SDÜ Sağlık Bilim Derg 2022;13(1):48-59. google scholar
• Harnett JE, Ung COL. Towards defining and supporting pharmacists’ professional role associated with traditional and complementary medicines-A systematic literature review. Res Social Adm Pharm 2023;19(3):356-413. google scholar
• San San Tan C, Wen Huey Lee S, Lagoon Selatan J, Sunway B. Warfarin and food, herbal or dietary supplement interactions: a systematic review. Br J Clin Pharmacol 2021;87(2):352-74. google scholar
• Rashrash M, Schommer JC, Brown LM. Prevalence and Predictors of Herbal Medicine Use Among Adults in the United States. J Patient Exp 2017;4(3):108-13. google scholar
• Fakeye TO, Onyemadu O. Evaluation of knowledge base of hospital pharmacists and physicians on herbal medicines in Southwestern Nigeria. Pharm Pract 2008;6(2):88-92. google scholar
• Apikoglu-Rabus S, Sancar M, Okuyan B, Izzettin FV. Turkish pharmacy technicians’ counseling practices and attitudes regarding emergency contraceptive pills. African Journal of Pharmacy and Pharmacology 2011;5(1):60-6. google scholar
• Baypınar MŞ. The evaluation of the awareness of pharmacists on the ınteraction between widely used herbal products and drugs (Master Thesis). Ankara: Hacettepe Univ. 2019. google scholar
• Carr A, Santanello C. Pharmacists’ knowledge, perceptions, and practices regarding herbal medicine. Inov Pharm 2019;10(3):15. google scholar
• Oshikoya KA, Oreagba IA, Ogunleye OO, Oluwa R, Senbanjo IO, Olayemi SO. Herbal medicines supplied by community pharmacies in Lagos, Nigeria: pharmacists’ knowledge. Pharm Pract 2013;11(4):219-27. google scholar
• Bardak F. Pharmacists’ self drug application cases. J Curr Nurs Res 2021;1(1):20-31. google scholar
• Klepser TB, Doucette WR, Horton MR, Buys LM, Ernst ME, Ford JK, et al. Assessment of patients’ perceptions and beliefs regarding herbal therapies. Pharmacotherapy 2000;20(1):83-7. google scholar
• Radwan A, Sweileh A, Shraim WA, Hroub A, Elaraj J, Shraim N. Evaluation of community pharmacists’ knowledge and awareness of food-drug interactions in Palestine. Int J Clin Pharm 2018;40(3):668-75. google scholar
• Zawiah M, Yousef A-M, Khan AH, ALAshwal FY, Matar A, ALKhawaldeh B, et al. Food-drug interactions: Knowledge among pharmacists in Jordan. PLoS ONE 2020;15(6):e0234779 google scholar
• Crighton E, Coghlan ML, Farrington R, Hoban CL, Power MWP, Nash C, et al. Toxicological screening and DNA sequencing detects contamination and adulteration in regulated herbal medicines and supplements for diet, weight loss and cardiovascular health. google scholar
• Corum D, Üney K. Nutrient-drug interactions. Dicle Üniversitesi Veteriner Fakültesi Dergisi 2017;10(1):38-55. google scholar
• Bushra R, Aslam N, Khan AY. Food-drug interactions. Oman Med J 2011;26(2):77-83. google scholar
• Bailey DG, Malcolm J, Arnold O, Spence JD. Grapefruit juice-drug interactions. Br J Clin Pharmacol 1998;46(2):101-10. google scholar
• Ovesen L, Lyduch S, Idorn ML. The effect of a diet rich in brussels sprouts on warfarin pharmacokinetics. Eur J Clin Pharmacol 1988;34(5):521-3. google scholar
• Karlson B, Leijd B, Hellström K. On the influence of vitamin K rich vegetables and wine on the effectiveness of warfarin treatment. Acta Med Scand 1986;220(4):347-50. google scholar