Electrocardiographic Evaluation in Patients with Endemic Fluorosis without Clinically Evident Heart Disease

Year 2010, Volume: 17 Issue: 4, 9 - 14, 30.12.2010

Ercan Varol

Abstract

Klinik olarak belirgin kalp hastalığı olmayan endemik florozisli hastaların elektrokardiyografik bulguları
Amaç: Bu çalışma endemik florozisli hastaların elektrokardiyografik (EKG) bulgularının incelenmesi açısından yapıldı. Ellialtı endemik florozis hastası ve yaş, cinsiyet ve vücut kütle indeksi eşitlenmiş 44 sağlıklı bireyin standart 12 derivasyon EKG si, idrar flor düzeyi ve serum sodium, potasyum, kalsiyum ve fosfor analizi yapıldı. Temel EKG ölçümleri ve EKG değişkliklerinin frekansı değerlendirildi. Bulgular: İdrar flor düzeyleri floroz hastalarında kontrol grubuna göre anlamlı derecede yüksekti (1.9 ± 0.2 mg/l vs. 0.4 ± 0.1 mg/l sırasıyla; P<0.001). Yaş, cinsiyet, vücut kütle indeksi ve serum sodium, potasyum, kalsiyum ve fosfor düzeyleri açısından kontrol grubu ve florozis hastaları arasında istatistiksel açıdan fark yoktu. Kalp hızı, temel EKG ölçümleri ve EKG değişiklikleri açısından kontrol grubu ve florozis hastaları arasında istatistiksel olarak anlamlı fark yoktu. Sonuç: Endemik florozun EKG üzerine etksi olmadığı sonucuna vardık.
Objective: This study was carried out to analyse the electrocardiogram (ECG) in patients with endemic fluorosis. Methods: Fifty six patients with endemic fluorosis and 44 age, sex and body mass index (BMI) matched healthy controls with normal fluoride intake underwent standart 12-lead ECG, urine fluoride level and serum sodium, potassium, calcium and phosphorus determination. Basic ECG measurements and frequency of ECG abnormalities were evaluated. Results: The urine fluoride levels of fluorosis patients were significantly higher than control subjects as expected (1.9 ± 0.2 mg/l vs. 0.4 ± 0.1 mg/l respectively; P<0.001). There were no statistically significant differences between the two groups with respect to age, gender, BMI and serum levels of sodium, potassium, calcium and phosphorus. There were no statistically significant differences between controls and fluorosis patients with respect to heart rate, basic ECG measurements and ECG abnormalities. Results: We concluded that endemic fluorosis has no effect on ECG

Keywords

endemik florozis, elektrokardiyogram

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