Abstract
Ülkemizde Doğu Karadeniz ve çevresinde daha sık görülen deli bal zehirlenmesi nadir bir zehirlenme türüdür. Zehirlenmede hipotansiyon ve bradikardi en sık görülen semptomlardır. Zehirlenmeden sorumlu olan grayanotoksin (andromedotoksin), rhododendron türü yaban çiçeklerinden arıların elde ettiği balda yoğun olarak bulunan bir toksindir. Sunulan vakada deli bal alımı sonrası hayatı tehdit edici hipotansiyon ve bradikardi semptomlarının geliştiği 72 yaşında erkek olguyu son literatür bilgisiyle anlatmayı amaçladık.
Anahtar Kelimeler: Bradikardi, grayanotoksin, deli bal zehirlenmesi
Keywords
References
- Gündüz A, Tatlý Ö, Türedi S. Geçmiþten günümüze deli bal zehirlenmesi. Turk J Emerg Med 2008;8:46- 9.
- Sutlupinar N, Mat A, Satganoglu Y. Poisoning by toxic honey in Turkey. Arch Toxicol 1993;67:148-50.
- Gündüz A, Meriçé ES, Baydýn A, et al. Does mad honey poisoning require hospital admission? Am J Emerg Med 2009;27:424-7.
- Baþgül A. Deli Bal Zehirlenmesi. Yoðun Bakým Dergisi 2003;3:33-6.
- Gündüz A, Turedi S, Uzun H, Topbas M. Mad honey poisoning. Am J Emerg Med 2006;24:595-8.
- Aliyev F, Türkoðlu C, Çeliker C, Firatli Ý, Alici G, Uzunhasan I. Chronicmad honey intoxication syndrome: a new form of an old disease? Europace 2009;11:954- 6.
- Koca I, Koca AF. Poisoning by mad honey: A brief review. Food Chem Toxicol 2007;45:1315-8.
- Leach DG. Ancient curse of the rhododendron. Am Horticulturist. 1972;51:20-29.
- Koçak S, Uçar K, Gül M. Deli bal zehirlenmesi. Genel Týp Dergisi 2008;18:137-8.
- Kurtoðlu S. Zehirlenmeler, Teþhis ve Tedavi. Kayseri: Erciyes Ünv. Yayýnlarý, No:30, 1992:569-70
- Seyamal I, Yamaoka K, Yakehiro M, Yoshioka Y, Morihara K. Is the site of action of grayanotoxin the sodium channel gating of squid axon? Jpn J Physiol 1985; 35: 401-10.
- Onat FY, Yegen BC, Lawrence R, et al. Site of action of grayanotoxins in mad honey in rats. J Appl Toxicol 1991;11:199-201.
- Onat FY, Yegen BC, Lawrence R, et al. Mad honey poisoning in man and rat. Rev Environ Health 1991;3:3- 9.
- Choi YS, Jang IS. A case of severe bradyarrhythmia after ingestion of rhododendron bradycarpum. Korean Circulation J 2002;32:268-70.
- Gunduz A, Durmus I, Turedi S, Nuhoglu I, Ozturk S. Mad honey poisoning related asystole. Emerg Med J 2007;24:592-3.
- Dursunoglu D, Gur S, Semiz E. A case with complete atrioventricular block related to mad honey intoxication. Ann Emerg Med 2007;50:484-5.
Abstract
Mad honey poisoning; a case reportMad honey intoxication is the cause of a rare food poisoning which has been known from ancient times inthe Eastern Black Sea region of Turkey. The most frequent symptoms of the intoxication are hypotensionand bradycardia. The poisoning is due to the concentrated grayanotoxine (andromedotoxine) content of thehoney made by the bees from the wild flowers of the rhodendron species. In this case report, we presenteda case of a 72- year-old man showing life threatining symptoms of hypotension and bradycardia followingthe ingestion of mad honey under the light of the literature
References
- Gündüz A, Tatlý Ö, Türedi S. Geçmiþten günümüze deli bal zehirlenmesi. Turk J Emerg Med 2008;8:46- 9.
- Sutlupinar N, Mat A, Satganoglu Y. Poisoning by toxic honey in Turkey. Arch Toxicol 1993;67:148-50.
- Gündüz A, Meriçé ES, Baydýn A, et al. Does mad honey poisoning require hospital admission? Am J Emerg Med 2009;27:424-7.
- Baþgül A. Deli Bal Zehirlenmesi. Yoðun Bakým Dergisi 2003;3:33-6.
- Gündüz A, Turedi S, Uzun H, Topbas M. Mad honey poisoning. Am J Emerg Med 2006;24:595-8.
- Aliyev F, Türkoðlu C, Çeliker C, Firatli Ý, Alici G, Uzunhasan I. Chronicmad honey intoxication syndrome: a new form of an old disease? Europace 2009;11:954- 6.
- Koca I, Koca AF. Poisoning by mad honey: A brief review. Food Chem Toxicol 2007;45:1315-8.
- Leach DG. Ancient curse of the rhododendron. Am Horticulturist. 1972;51:20-29.
- Koçak S, Uçar K, Gül M. Deli bal zehirlenmesi. Genel Týp Dergisi 2008;18:137-8.
- Kurtoðlu S. Zehirlenmeler, Teþhis ve Tedavi. Kayseri: Erciyes Ünv. Yayýnlarý, No:30, 1992:569-70
- Seyamal I, Yamaoka K, Yakehiro M, Yoshioka Y, Morihara K. Is the site of action of grayanotoxin the sodium channel gating of squid axon? Jpn J Physiol 1985; 35: 401-10.
- Onat FY, Yegen BC, Lawrence R, et al. Site of action of grayanotoxins in mad honey in rats. J Appl Toxicol 1991;11:199-201.
- Onat FY, Yegen BC, Lawrence R, et al. Mad honey poisoning in man and rat. Rev Environ Health 1991;3:3- 9.
- Choi YS, Jang IS. A case of severe bradyarrhythmia after ingestion of rhododendron bradycarpum. Korean Circulation J 2002;32:268-70.
- Gunduz A, Durmus I, Turedi S, Nuhoglu I, Ozturk S. Mad honey poisoning related asystole. Emerg Med J 2007;24:592-3.
- Dursunoglu D, Gur S, Semiz E. A case with complete atrioventricular block related to mad honey intoxication. Ann Emerg Med 2007;50:484-5.
Details
| Primary Language | tu |
|---|---|
| Journal Section | Case Reports |
| Authors | |
| Publication Date | December 30, 2013 |
| Submission Date | August 23, 2011 |
| Published in Issue | Year 2013 Volume: 20 Issue: 4 |
Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi/Medical Journal of Süleyman Demirel University is licensed under Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International.