Aşırı Doz Siklopentolat Göz Damlasına Bağlı Gelişen Santral Antikolinerjik Sendrom

Year 2018, Volume: 25 Issue: 3, 333 - 335, 01.09.2018

Mehmet Barış Üçer , Hülya Gökmen Soysal

https://doi.org/10.17343/sdutfd.365015

Abstract

Siklopentolat hidroklorür %1 damla göz
kliniklerinde çok sık kullanılan topikal midriyatik ve sikloplejik bir ilaçtır.
Bu olguda sekiz yaşındaki hastaya yanlışlıkla toplamda 16 damla siklopentolat
hidroklorür %1 döküldükten sonra gelişen santral antikolinerjik sendrom
sunulmuştur. Dizartri, ataksik yürüyüş, görsel halüsinasyon, ağız şapırdatma,
dizoryantasyon ve yüzde kızarıklık gelişen hasta, tıbbi gözetim altında
tutulmuş ve tüm bulgular 6 saat içinde spontan düzelmiştir. Özellikle uygun
dozda kullanılmayan siklopentolat göz damlasına bağlı sistemik yan etkiler
gelişebileceği için bu hastalar gözlem altında tutulmalıdır.

Keywords

Siklopentolat hidroklorür %1, toksisite, , aşırı doz

Central Anticholinergic Syndrome Induced by Overdose Cyclopentolate Eye Drops

Abstract

Cyclopentolate hydrochloride %1 is a commonly used drug
as a topical mydriatic and cycloplegic agent in ophthalmology clinics. In this report, an eight years old
patient was presented who diagnosed as central anticholinergic syndrome after
accidental instillation of a total dose of 16 drops cyclopentolate
hydrochloride %1. Patient was strickly monitered as for the symptoms of dysarthria,
gait ataxia, visual hallucination, mouth sneezing, disorientation and facial redness.
All findings were resolved spontaneously within 6 hours. Cyclopentolate eye
drops can cause systemic side effects especially if not used at appropriate
dose, thus these patients should be observed.

Keywords

Cyclopentolate hydrochloride %1, toxicity, overdose

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