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ÜRETER DUBPLİKASYONLU GREFT BÖBREKLERDE NAKİL TECRÜBEMİZ

Year 2019, Volume: 26 Issue: 2, 195 - 200, 01.06.2019
https://doi.org/10.17343/sdutfd.499151

Abstract

ÜRETER DUPLİKASYONU OLAN GREFT BÖBREKLERDE BÖBREK NAKLİ
TECRÜBEMİZ



Amaç:
Kronik
böbrek yetmezliğininin en etkili, tedavisi böbrek naklidir . Böbrek nakli
sonrası ürolojik komplikasyonlar, 
morbiditeyi arttırmaktadır . Üreter duplikasyonu       ( ÜD), üst üriner sistemin en sık
görülen anomalisidir . ÜD prevalansı, % 0.6-% 1, arasında değişmektedir. ÜD’lu
böbrek greftlerinde yapılacak üreter mesane anastomuzunun nasıl yapılacağı
ilgili görüş birliği yoktur. Bu çalışmamızda, kliniğimizde yapılmış olan ÜD'lu renal
transplantasyon tecrübelerimizi ve sonuçlarımızı paylaşmayı amaçladık.



Gereç
ve
Yöntem: Ocak
2013-  Aralık 2017 tarihleri arasında
Antalya Medicalpark Organ Nakli Bölümünde ÜD’li greft böbrek ile  böbrek nakli yapılan hastaların sonuçları
retrospektif olarak analiz edildi. Hastaların yaş, cinsiyet, donör türü, donör
yaşı, donör ameliyatının tipi, böbrek nakli sonrası takip süresi, ortalama
ameliyat süresi, böbrek nakliöncesi dializ türleri, böbrek nakli sayısı, böbrek
nakli sonrası üriner komplikasyonlara, kreatinin düzeyi, greft sağ kalımı ile
birlikte  hasta sağ kalımına
değerlendirildi.



Bulgular:
Merkezimizde
ocak 2013- aralık 2017 tarihleri arasında 2039 böbrek nakli yapıldı. Olguların
28 (% 0,1)’inde ÜD saptandı. Hastaların ortalama yaşı 38 .07 ±14.7 (range
8-60). Erkek kadın oranı 1.1 di. Böbrek alıcılarının 15’i erkek 13'ü kadındı,
böbrek donörlerinin  22'si canlı 6'sı
kadavraydı. Donörlerde (kadın, erkek )oranı 3 saptandı. Ortalama donör yaşı
48.6 ± 15.5 (14-81) di. 13 hasta preemptif, 14 hasta hemodializ, 1 hasta
da  periton dializi yapmakta idi.
Ortalama ameliyat süresi 80.6±13.4 dakika (65-109). Bir hastada böbrek nakli
sonrası 2. ayda idrar kaçağı oluştu (%3.5). Diğer hastalarda üriner
komplikasyon saptanmadı.



Sonuç: Böbrek
naklinde  greft böbreklerde ÜD böbrek
nakli için engel kabul edilmemelidir, tecrübelerimize göre ÜD olan greft
böbreklerde tek ostiumlu
Lich Gregoir Üreteroneosistostomi,
yöntemi, 2 adet DJS kullanılarak yapılması, diğer  yöntemlere göre daha güvenlidir.



Anahtar Kelimeler:
Böbrek Transplantasyonu, Üreter dublikasyonu,
Üreteroneosistostomi, Komplikasyon



 



OUR EXPERİNCE WİTH
KİDNEY TRANSPLANTAİON IN KIDNEYS WİTH URETER DUPLİCATİON



Purpose: The most effective treatment of chronic renal failure is
kidney transplantation. Urological complications after kidney transplantation
increase morbidity. Ureter duplication (UD) is the most common anomaly of the
upper urinary tract. . There is no consensus on how to perform ureter bladder
anastomosis in kidney grafts with double ureters. In this study, we aimed to
share our experience and results of renal transplantation with grafts having UD
anomaly performed in our clinic.

Methods: Between January 2013 and
December 2017, the results of transplantations at Antalya Medical Park
Transplantation Center with kidney grafts which had ureteral duplication were
analyzed retrospectively . Age, sex, donor type, age of donor, type of donor
operation, duration of renal transplantation, mean operation time, pre-renal
dialysis types, number of kidney transplants, urinary complications after
kidney transplantation, creatinine level, graft surviv and patient survival
were evaluated

Results: Between January 2013 and
December 2017, 2039 kidney transplants were performed in our transplantation
center. UD was detected in 28 cases (0.1%). The mean age of donors was 48.6 ±
15.5 (14-81).  The mean operative time
was 80.6 ± 13.4 minutes (65-109). Urinary leakage occurred in one patient
(3.5%) within the 2 months after renal transplantation .There were no urinary
complications in other patients

Conclusion:In renal transplantation, the
graft with ureteral duplication should not be considered as an obstacle for
renal transplantation .We experienced that
Lich Gregoir Ureteroneocystostomy  method with single-ostium by using 2 Double –J
stents in the kidney grafts with UD is safer than other method.



Keywords: Kidney
transplantion, Ureter duplication Ureteroneocystostomy, Complications



 



 

References

  • 1. Ghazanfar A, Zaki MR, Pararajasingam R, Forgacs B, Tavakoli A. Outcome of Kidney Transplant With Double Ureter: A multi Center Study. Exp. Clin. Transplant., 2015;13 (2): 152–156
  • 2. F. Lasaponara, Dalmasso E, Bosio A, Pasquale G, Sedigh O, Santià S, at all. Kidney Transplant Graft Swith Complete Ureteral Duplication. Experimentaland Clinical Transplantation 2013;6: 507-509 3. Sulikowski T, Zie Z˛ Ostrowski M, Kamin M, Sien J, Romanowski M, at all .Experiences in Kidney Transplantation With Duplicated Ureters. Transplant. Proc.2005;37( 5): 2096–2099
  • 4. Sarier M, Demir M, Goktas S, Duman I,Buyukkınaci M, Yuksel Y, at all . Results of Real-time Multiplex Polymerase Chain Reaction Assay in Renal Transplant Recipients With Sterile Pyuria. Transplant Proc. 2017;49(6):1307-1311. doi:10.1016/j.transproceed.2017.02.051
  • 5. Alberts VP, Minnee RC, K.A.M.I. van Donselaarevan KAMI, Bemelman FJ, Zondervan PJ, Laguna MP, at all. MM .Duplicated Uretersand Renal Transplantation: A Case-Control StudyandReview of the Literature. Transplant. Proc.2013;45 (9): 3239–3244
  • 6. Kayler L, Kang D, Molmenti E, and Howard R. Kidney Transplant Ureteroneocystostomy Techniques and Complications: Review of the Literature. Transplant. Proc.2013; 42 (5): 1413–1420
  • 7. Sözen H, Onaran M, Özen O, Dalgıç A. Urologic Complications After Renal Transplant: A Single-Center Experience. Experimental and Clinical Transplantation (2017): 2-5 DOI: 10.6002/ect.2016.0281
  • 8. Dinckan A,Tekin A,Turkyilmaz S, Kocak H, Gurkan A, Erdogan O, at all. Early and Late Urological Complications Corrected Surgically Following Renal Transplantation. European Society for Organ Transplantation 2007;20: 702–707
  • 9. Haferkamp A, Dörsam J, Möhring K, Wiesel M, and Staehler G. Ureteral Complications in Renal Transplantation With More Than One Donor Ureter, Nephrol. Dial. Transplant.1999;14 (6): 1521–1524
  • 10. Uchida J, Naganuma T, Machida Y, Kitamoto K, YamazakiT, Iwai T at all. Modified extravesica lureteroneocystostomy for completely duplicated ureters in renal transplantation. Urol. Int. 2006;77 (2): 104–106
  • 11. Nagashima N, Saitoh N, Arai T, Watanabe T, and Koyama I. Double Ureteroneocystostomy for Duplicated Allograft Ureters in Renal Transplantation. Transplant. Proc.2003; 35( 1) 334–336
  • 12. Genyk Y, Knight R, DeCsepel J, and Burrows L. Successful Transplantation of Pediatric on Bloc Kidneys With Bilateral Duble Ureters. Transpl. Int. 1999; 12( 4): 281–282
  • 13. Alberts VP, Idu MM, Legemate DA, Laguna MP and Minnee RC. Ureterovesical anastomotic techniques for kidney transplantation: a systematic review and meta-analysis. Transplant International. 2014: 593–605
  • 14. Heidari M, Gharaati MR, Iran-Pour E, Simforoosh N, Zare S, and BasiriA.Transplantation of Kidneys With Duplicated ureters. Scand. J. Urol. Nephrol. 2010; 44 (5): 337–340
  • 15. Yuksel Y, Tekin S, Yuksel D, Duman I, Sarier M, Yucetin L, at all. Optimal Timing for Removal of the Double-J Stent After Kidney Transplantation. Transplantation Proceedings. 2017; 49:523-527
  • 16. Bozkurt B, Tokaç M, Dumlu EG, Yarar, Ö and Kılıç M. Transplantation Technologies & Modified ExtravesicalUreteroneocystostomy in Cadaveric Kidney Transplantation with Completely Duplicated Ureters : A Case Report. 2014; 4(2): 10–12
  • 17. JBustosa JJS, Gomeza EG, Hernándeza JPC, Valientea JC, Garcíaa JR, Lópeza FJM,at all. MJR. Initial Experience in the Use of Novel Auto-expandable Metal Ureteral Stent in the Treatment of Ureter Stenosis in Kidney Transplanted Patients. Transplantation Proceedings. 2018; (50): 587-590
Year 2019, Volume: 26 Issue: 2, 195 - 200, 01.06.2019
https://doi.org/10.17343/sdutfd.499151

Abstract

References

  • 1. Ghazanfar A, Zaki MR, Pararajasingam R, Forgacs B, Tavakoli A. Outcome of Kidney Transplant With Double Ureter: A multi Center Study. Exp. Clin. Transplant., 2015;13 (2): 152–156
  • 2. F. Lasaponara, Dalmasso E, Bosio A, Pasquale G, Sedigh O, Santià S, at all. Kidney Transplant Graft Swith Complete Ureteral Duplication. Experimentaland Clinical Transplantation 2013;6: 507-509 3. Sulikowski T, Zie Z˛ Ostrowski M, Kamin M, Sien J, Romanowski M, at all .Experiences in Kidney Transplantation With Duplicated Ureters. Transplant. Proc.2005;37( 5): 2096–2099
  • 4. Sarier M, Demir M, Goktas S, Duman I,Buyukkınaci M, Yuksel Y, at all . Results of Real-time Multiplex Polymerase Chain Reaction Assay in Renal Transplant Recipients With Sterile Pyuria. Transplant Proc. 2017;49(6):1307-1311. doi:10.1016/j.transproceed.2017.02.051
  • 5. Alberts VP, Minnee RC, K.A.M.I. van Donselaarevan KAMI, Bemelman FJ, Zondervan PJ, Laguna MP, at all. MM .Duplicated Uretersand Renal Transplantation: A Case-Control StudyandReview of the Literature. Transplant. Proc.2013;45 (9): 3239–3244
  • 6. Kayler L, Kang D, Molmenti E, and Howard R. Kidney Transplant Ureteroneocystostomy Techniques and Complications: Review of the Literature. Transplant. Proc.2013; 42 (5): 1413–1420
  • 7. Sözen H, Onaran M, Özen O, Dalgıç A. Urologic Complications After Renal Transplant: A Single-Center Experience. Experimental and Clinical Transplantation (2017): 2-5 DOI: 10.6002/ect.2016.0281
  • 8. Dinckan A,Tekin A,Turkyilmaz S, Kocak H, Gurkan A, Erdogan O, at all. Early and Late Urological Complications Corrected Surgically Following Renal Transplantation. European Society for Organ Transplantation 2007;20: 702–707
  • 9. Haferkamp A, Dörsam J, Möhring K, Wiesel M, and Staehler G. Ureteral Complications in Renal Transplantation With More Than One Donor Ureter, Nephrol. Dial. Transplant.1999;14 (6): 1521–1524
  • 10. Uchida J, Naganuma T, Machida Y, Kitamoto K, YamazakiT, Iwai T at all. Modified extravesica lureteroneocystostomy for completely duplicated ureters in renal transplantation. Urol. Int. 2006;77 (2): 104–106
  • 11. Nagashima N, Saitoh N, Arai T, Watanabe T, and Koyama I. Double Ureteroneocystostomy for Duplicated Allograft Ureters in Renal Transplantation. Transplant. Proc.2003; 35( 1) 334–336
  • 12. Genyk Y, Knight R, DeCsepel J, and Burrows L. Successful Transplantation of Pediatric on Bloc Kidneys With Bilateral Duble Ureters. Transpl. Int. 1999; 12( 4): 281–282
  • 13. Alberts VP, Idu MM, Legemate DA, Laguna MP and Minnee RC. Ureterovesical anastomotic techniques for kidney transplantation: a systematic review and meta-analysis. Transplant International. 2014: 593–605
  • 14. Heidari M, Gharaati MR, Iran-Pour E, Simforoosh N, Zare S, and BasiriA.Transplantation of Kidneys With Duplicated ureters. Scand. J. Urol. Nephrol. 2010; 44 (5): 337–340
  • 15. Yuksel Y, Tekin S, Yuksel D, Duman I, Sarier M, Yucetin L, at all. Optimal Timing for Removal of the Double-J Stent After Kidney Transplantation. Transplantation Proceedings. 2017; 49:523-527
  • 16. Bozkurt B, Tokaç M, Dumlu EG, Yarar, Ö and Kılıç M. Transplantation Technologies & Modified ExtravesicalUreteroneocystostomy in Cadaveric Kidney Transplantation with Completely Duplicated Ureters : A Case Report. 2014; 4(2): 10–12
  • 17. JBustosa JJS, Gomeza EG, Hernándeza JPC, Valientea JC, Garcíaa JR, Lópeza FJM,at all. MJR. Initial Experience in the Use of Novel Auto-expandable Metal Ureteral Stent in the Treatment of Ureter Stenosis in Kidney Transplanted Patients. Transplantation Proceedings. 2018; (50): 587-590
There are 16 citations in total.

Details

Primary Language Turkish
Subjects Surgery
Journal Section Research Articles
Authors

Yucel Yuksel

Publication Date June 1, 2019
Submission Date December 18, 2018
Acceptance Date February 4, 2019
Published in Issue Year 2019 Volume: 26 Issue: 2

Cite

Vancouver Yuksel Y. ÜRETER DUBPLİKASYONLU GREFT BÖBREKLERDE NAKİL TECRÜBEMİZ. Med J SDU. 2019;26(2):195-200.

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