Abstract
Introduction: Penile metastasis of
rectum cancer is very rare. There are only 40 cases in the literature. In this case report, we aimed to present a case
of penile metastasis of rectum cancer which is very rare in the literature.
Case Report: We report a case of a 70
years old patient who presented with urinary retention and painful ulcerated
nodules on the penis. He had undergone low anterior resection for rectum cancer
after neoadjuvant chemotherapy 3 years previously. We performed an 18F-labeled
fluoro-2-deoxyglucose Positron Emission Tomography (18F-FDG PET/CT). It revealed that there was recurrence at
pelvic area and metastasis on the penis. Biopsy of the nodules showed penile
metastasis of rectum cancer.
Conclusion: Despite its rich blood
supply and closeness to the pelvic organs, penile metastasis is very rare.
Metastatic spreading mechanism is not well established. Penile metastasis has a
very poor prognosis and there is insufficient data for the treatment of penile
metastasis in the literature. Palliative treatments should be considered with
or without survival benefits.
Keywords
References
- 1-Eberth CJ. Krebsmetastasen des corpus cavernosum penis. Virch Arch, 1870; 74: 145.
- 2-Ketata S, Boulaire JL, Soulimane B, Bargain A. Metachronous metastasis to the penis. Clin Colorectal Cancer, 2007; 6: 657-659.
- 3-Andrea Cocci, Oliver W. Hakenberg, Tommaso Cai, Gabriella Nesi, Lorenzo Livi, Beatrice Detti, et al. Prognosis of men with penile metastasis and malignant priapism: a systematic review. Oncotarget, 2018; 9(2): 2923–2930.
- 4-Cherian J, Rajan S, Thwaini A, Elmasry Y, Shah T, Puri R. Secondary penile tumours revisited. Int Semin Surg Oncol, 2006; 3: 33.
- 5-Chaux A, Amin M, Cubilla AL, Young RH. Metastatic tumors to the penis: a report of 17 cases and review of the literature. Int J Surg Pathol, 2011; 19(5): 597–606.
- 6-Kuliavas J, Dulskas A,, Drachneris J, Miseikyte-Kaubriene E, Samalavicius NE. Penile Metastasis from Rectal Carcinoma: Case Report and Review of the Literature. Visc Med, 2018; 34(5): 389-392
- 7- Zhang K, Da J, Yao HJ, Zheng DC, Cai ZK, Jiang YQ, et al. Metastatic tumors of the penis: a report of 8 cases and review of the literature. Medicine (Baltimore), 2015; 94(1): 132.
- 8-Zheng FF, Zhang ZY, Dai YP, Liang YY, Deng CH, Tao Y. Metastasis to the penis in a patient with adenocarcinoma of lung, case report and literature review. Med Oncol, 2009; 26: 228–232.
- 9-Kimura Y, Shida D, Nasu K, Matsunaga H, Warabi M, Inoue S. Metachronous penile metastasis from rectal cancer after total pelvic exenteration. World J Gastroenterol, 2012; 18: 5476–5478.
- 10-Ben-Yosef R, Kapp DS. Cancer metastatic to the penis: treatment with hyperthermia and radiation therapy and review of the literature. J Urol, 1992; 148: 67–71.
Abstract
Amaç: Rektum
kanserinin penise metastazı oldukça az görülen bir olgudur. Biz bu olgu
sunumunda literatürde sınırlı sayıda bildirilmiş ve çok nadir bir olgu olan rektum
kanserinin penise metastazı olgumuzu sunmayı hedefledik.
Olgu : 70
yaşında erkek hasta tarafımıza akut üriner retansiyon ve penis üzerinde ağrılı
ülsere lezyonlar ile başvurdu. Hastanın 3 sene önce rektum kanseri nedeniyle neoadjuvan
kemoterapi ve ardından aşağı anterior rezeksiyon ameliyatı geçirdiği öğrenildi.
Çekilen PET BT’ de pelvik bölgede nüks ve penis üzerinde metastastik nodüller görüldü.
Penis üzerindeki nodüllerden alınan eksizyonel biyopside rektum kanserinin
penise metastazı olduğu histopatolojik olarak anlaşıldı.
Sonuç: Zengin kanlanmasına ve pelvik organlara yakınlığına
rağmen, penis metastazı çok nadir görülür. Penise metastatik yayılımın
mekanizması tam anlaşılamıştır. Çok kötü prognozludur ve
literatürde penis metastazı tedavisi için yeterli veri yoktur. Tedavide palyatif tedaviler sağkalım faydaları
olsun veya olmasın düşünülmelidir.
References
- 1-Eberth CJ. Krebsmetastasen des corpus cavernosum penis. Virch Arch, 1870; 74: 145.
- 2-Ketata S, Boulaire JL, Soulimane B, Bargain A. Metachronous metastasis to the penis. Clin Colorectal Cancer, 2007; 6: 657-659.
- 3-Andrea Cocci, Oliver W. Hakenberg, Tommaso Cai, Gabriella Nesi, Lorenzo Livi, Beatrice Detti, et al. Prognosis of men with penile metastasis and malignant priapism: a systematic review. Oncotarget, 2018; 9(2): 2923–2930.
- 4-Cherian J, Rajan S, Thwaini A, Elmasry Y, Shah T, Puri R. Secondary penile tumours revisited. Int Semin Surg Oncol, 2006; 3: 33.
- 5-Chaux A, Amin M, Cubilla AL, Young RH. Metastatic tumors to the penis: a report of 17 cases and review of the literature. Int J Surg Pathol, 2011; 19(5): 597–606.
- 6-Kuliavas J, Dulskas A,, Drachneris J, Miseikyte-Kaubriene E, Samalavicius NE. Penile Metastasis from Rectal Carcinoma: Case Report and Review of the Literature. Visc Med, 2018; 34(5): 389-392
- 7- Zhang K, Da J, Yao HJ, Zheng DC, Cai ZK, Jiang YQ, et al. Metastatic tumors of the penis: a report of 8 cases and review of the literature. Medicine (Baltimore), 2015; 94(1): 132.
- 8-Zheng FF, Zhang ZY, Dai YP, Liang YY, Deng CH, Tao Y. Metastasis to the penis in a patient with adenocarcinoma of lung, case report and literature review. Med Oncol, 2009; 26: 228–232.
- 9-Kimura Y, Shida D, Nasu K, Matsunaga H, Warabi M, Inoue S. Metachronous penile metastasis from rectal cancer after total pelvic exenteration. World J Gastroenterol, 2012; 18: 5476–5478.
- 10-Ben-Yosef R, Kapp DS. Cancer metastatic to the penis: treatment with hyperthermia and radiation therapy and review of the literature. J Urol, 1992; 148: 67–71.
Details
| Primary Language | Turkish |
|---|---|
| Subjects | Clinical Sciences |
| Journal Section | Case Reports |
| Authors | |
| Publication Date | June 1, 2020 |
| Submission Date | April 23, 2019 |
| Acceptance Date | July 2, 2019 |
| Published in Issue | Year 2020 Volume: 27 Issue: 2 |
Süleyman Demirel Üniversitesi Tıp Fakültesi Dergisi/Medical Journal of Süleyman Demirel University is licensed under Creative Commons Attribution-NonCommercial-NoDerivs 4.0 International.