ERKEN EVRE MEME KANSERLİ HASTALARDA BEDEN KİTLE İNDEKSİ DEĞİŞİMİ VE OBEZİTEYE BAĞLI SAĞLIK KOMPLİKASYONLARI

Year 2021, Volume: 28 Issue: 4, 591 - 597, 30.12.2021

Muhammet Cüneyt Bilginer , Halil Kavgacı

https://doi.org/10.17343/sdutfd.880502

Abstract

Amaç
Görüntüleme yöntemlerindeki gelişmeler ve multimodal
tedaviler, sağ kalan meme kanserli hasta sayısında
artışa neden olmuştur. Bu durum sağ kalımı
artıracak değiştirilebilir risk faktörlerinin araştırılması
gerektiğini düşündürmektedir. Biz bu çalışmada erken
evre meme kanserli hastaların takibinde ortaya çıkan
beden kitle indeksi (BKİ) değişikliklerini ve bu değişikliklerin
yol açabileceği obezite ile ilişkili sağlık sorunlarını
tespit etmeyi amaçladık.
Gereç ve Yöntem
Kliniğimize başvuran ‘‘Erken evre meme kanseri’’ tanısı
almış 142 hastanın BKİ (tanı anındaki), güncel
BKİ (tanita) ile karşılaştırılmıştır. BKİ’deki değişimlerle
obezite ilişkili sağlık sorunları arasındaki ilişki araştırılmıştır.
Bulgular
Hastaların ortalama yaşı 52,7 ± 1,1 (31-78) olup tamamı
kadın hasta idi. Tanı anında hastaların % 56,3
premenapozal, % 43,7 postmenapozal idi. Hastaların
tanıda BKİ ortalaması 27,9 ± 5,3 iken güncel BKİ
ortalaması 30,7 ± 5,7 olarak hesaplandı (p<0,0001).
Hastaların %90,8’inde (n=129) BKİ’de artış, %8’ inde
(n=11) BKİ’de azalma, % 1,2’sinde (n=2) ise BKİ'de
değişme olmadığı tespit edildi. BKİ’de artış olan hastalar,
hastalık yaşına göre incelendiğinde hastalığının
ilk yılında olanlarda BKİ artışı 2,1±1,6 kg/m² iken
hastalığının 5. yılı ve üzerinde olanlarda BKİ artışı
4,0±2,9 kg/m² olarak bulundu (p<0,017). BKİ’nde artış
tespit edilen hastaların %22.5’inde Diyabetes Mellitus,
%46.5’inde hipertansiyon, %40.3’ünde hiperlipidemi
ve %40.3’ünde dejeneratif osteoartrit tespit
edildi. Hastalığın başlangıcına göre karşılaştırıldığında
BKI’de artış tespit edilen hastalarda tüm bu tanılar
anlamlı oranda daha yüksekti (p<0,0001).
Sonuç
Erken evre meme kanserli hastalarda BKİ artışı yaygın
görülen bir problemdir. Kilo artışı obeziteye bağlı
gelişen kronik hastalıklarda artışa neden olmaktadır.
Meme kanseri hastalarını kilo artışı yönünden bilgilendirmek
tedavi yönetiminin bir parçası olmalıdır.

Keywords

Erken evre meme kanseri, beden kitle indeksi, Obezite, Kronik hastalıklar

Supporting Institution

Yok

CHANGES IN BODY MASS INDEX AND OBESITY RELATED HEALTH COMPLICATIONS AMONG EARLY-STAGE BREAST CANCER

Abstract

Objective
Advances in imaging methods and multimodal
therapies have led to an increase in the number of
breast cancer patients surviving. This suggests that
modifiable risk factors that will increase survival
should be investigated. In this study, we aimed to
determine the changes in body mass index (BMI) that
occur during the follow-up of patients with early stage
breast cancer and the health problems associated
with obesity that may be caused by these changes.
Material and Methods
Basal BMI (measured at diagnosis) of 142 patients
admitted to our clinic who were diagnosed with "earlystage
breast cancer" was compared with the current
BMI (tanita).The relationship between changes in BMI
and obesity-related health problems investigated.
Results
The mean age of the patients was 52.7 ± 1.1 (31-78),
and all of them were female. At the time of diagnosis,
56.3% of the patients were premenopausal and
43.7% postmenopausal. While the mean BMI of the
patients at diagnosis was 27.9 ± 5.3, the current
BMI was calculated as 30.7 ± 5.7 (p <0.0001). It was
determined that 90.8% (n = 129) of the patients had
an increase in BMI, 8% (n = 11) had a decrease in
BMI, and 1.2% (n = 2) had no change in BMI. When
the patients with an increase in BMI were examined
according to the age of the disease, the BMI increase
was found to be 2.1 ± 1.6 kg / m2 in the first year of the
disease, while the BMI increase was found to be 4.0
± 2.9 kg / m2 in the 5th year and more of the disease
(p <0.017). Diabetes Mellitus was detected in 22.5%
of patients with an increase in BMI, hypertension in
46.5%, hyperlipidemia in 40.3% and degenerative
osteoarthritis in 40.3%. All these diagnoses were
significantly higher in patients with an increase in BMI
compared to the onset of the disease (p <0.0001).
Conclusion
Increased BMI is a common problem in patients with
early stage breast cancer. Weight gain causes an
increase in chronic diseases due to obesity. Informing
breast cancer patients about weight gain should be a
part of treatment management.

Keywords

Early-stage breast cancer, body mass indeks, Obesity, Chronic diseases

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