BİR EĞİTİM VE ARAŞTIRMA HASTANESİNDE COVİD-19 ENFEKSİYONU NEDENİ İLE İMMÜN PLAZMA UYGULANAN HASTALARIN DEĞERLENDİRİLMESİ

Year 2022, Volume: 29 Issue: 2, 229 - 236, 30.06.2022

Derya Hırçın Cenger , Sevinç Yenice Aktaş Burcu İleri Fikri , Hatice Kutbay Merih Dilan Albayrak Sedat Altin

https://doi.org/10.17343/sdutfd.1006069

Abstract

Amaç
COVID-19 enfeksiyonu tedavisi için immün plazma
uygulanan hastaların demografik ve klinik verilerinin
ve immün plazma transfüzyonu ile ilişkili reaksiyonların
değerlendirilmesi amaçlanmıştır.
Gereç ve Yöntem
Etik kurul onayı alınılan çalışma, retrospektif ve tanımlayıcı
bir araştırmadır. 2020 yılında COVİD-19
enfeksiyonu nedeniyle immün plazma uygulanan 130
hasta çalışmaya dahil edildi. Hastaların dosyaları ve
transfüzyon merkezi sisteminde kayıtlı olan bilgileri
değerlendirilerek araştırmacılar tarafından SPSS paket
programı kullanılarak analiz edildi.
Bulgular
İmmün plazma klinik uygulama kriterlerini sağlayan
130 hastaya 154 kez immün plazma transfüzyon
uygulaması yapıldı. Hastaların bir ya da birden fazla
kötü prognostik ölçüte sahip, orta ve ağır pnömoni
hastaları olduğu, ortalama 17,9 gün hastanede
yatarak tedavi gördüğü, %35,4’ünde sürecin ölümle
sonuçlandığı belirlendi. İmmun plazma transfüzyon
reaksiyonu sıklığı %1,95 olarak saptandı. Anti - A antikoruna
sahip hastalarda %23,1’inde sürecin ölümle
sonuçlandığı belirlendi.
Sonuç
İmmün plazma uygulanan bir veya daha fazla kötü
prognostik kritere sahip orta ve şiddetli pnömonili hastalar
hakkında veri sağlanmasının literatüre katkıda
bulunabileceği düşünülmektedir.

Keywords

İmmun plazma, Prognoz, Transfüzyon reaksiyonu, ABO gruplar

EVALUATION OF PATIENTS WHO RECEIVED IMMUNE PLASMA DUE TO COVID-19 INFECTION IN AN EDUCATIONAL AND RESEARCH HOSPITAL

Abstract

Objective
It is aimed to evaluate the demographic and clinical data
of patients receiving immune plasma for the treatment
of COVID-19 infection and reactions associated with
uygulamaimmune
plasma transfusion.
Materials and Methods
The study, which received the approval of the ethics
committee, is a retrospective and descriptive study. In
2020, 130 patients who were administered immune
plasma due to COVID-19 infection were included in
the study. The patients' files and information stored
in the transfusion center system were evaluated and
analyzed by the researchers using the SPSS package
program.
Results
Immune plasma transfusion was performed 154
times in 130 patients who met the criteria for clinical
application of immune plasma. It was determined that
the patients had moderate and severe pneumonia with
one or more poor prognostic criteria, were hospitalized
for an average of 17.9 days, and the process resulted
in death in 35.4% of them. The frequency of immune
plasma transfusion reaction was found to be 1.95%. It
was determined that the process resulted in death in
23.1% of patients with anti - A antibody.
Conclusion
It is thought that the provision of data on patients with
moderate and severe pneumonia with one or more
poor prognostic criteria undergoing immune plasma
may contribute to the literature.

Keywords

Immune plasma, Prognosis, Transfusion reaction, ABO groups

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