NEUROSYPHILIS PRESENTING WITH PSYCHIATRIC SYMPTOMS: A CASE REPORT

Year 2022, Volume: 29 Issue: 4, 681 - 686, 27.12.2022

Şule Gül , Cicek Hocaoglu

https://doi.org/10.17343/sdutfd.1134041

Cited By: 1

Abstract

Syphilis is an infectious disease transmitted sexually
by spirochetes called Treponema Pallidum. Central
nervous system involvement can be observed in
any period. Neurosyphilis, which can cause clinical
manifestations similar to many psychiatric disorders
such as depression, mania, delirium, dementia and
personality changes, may cause some difficulties
in diagnostic evaluations. Therefore, neurosyphilis
should be considered in the differential diagnosis of
especially sudden and late-onset neurological and
psychiatric disorders. Although it is rarely seen today
with the widespread use of antibiotics, early diagnosis
and treatment of neurosyphilis is important. In this
paper, it is aimed to contribute to the current literature
by discussing the case of a 50-year-old female patient
who was admitted to our service with late-onset mania
symptoms and was diagnosed with neurosyphilis
during the examinations, in the light of the literature
findings.

Keywords

Neurosyphilis, Psychiatric Symptom, Treponema Pallidum

Project Number

yok

PSİKİYATRİK BELİRTİLER İLE BAŞVURAN NÖROSİFİLİZ: BİR OLGU SUNUMU

Abstract

Sifiliz, Treponema Pallidum adlı spiroketle cinsel yolla
bulaşan enfeksiyöz bir hastalıktır. Santral sinir sistemi
tutulumu her dönemde gözlenebilir. Depresyon, mani,
deliryum, demans ve kişilik değişiklikleri gibi çok sayıda
psikiyatrik bozukluklara benzer klinik görünümlere
neden olabilen nörosifiliz tanı ile ilgili değerlendirmelerde
bazı güçlüklere neden olabilmektedir. Bu
nedenle özellikle ani ve geç başlangıçlı nörolojik ve
psikiyatrik bozuklukların ayırıcı tanısında nörosifiliz
düşünülmelidir. Her ne kadar günümüzde antibiyotiklerin
yaygın kullanımı ile nadir olarak görülse de nörosifilizin
erken tanı ve tedavisi önemlidir. Genellikle birincil
enfeksiyondan 4-10 yıl sonra, tedavi edilmeyen
veya yetersiz tedavi gören olgularda nörosifiliz riski
artmıştır Bu yazıda geç başlangıçlı mani belirtileri ile
servisimize kabul edilen ve tetkikleri sırasında nörosifiliz
tanısı konulan 50 yaşındaki kadın olgu literatür
bulguları eşliğinde tartışılarak, mevcut yazına katkı
sunulması amaçlanmıştır.

Keywords

Nörosifiliz, Psikiyatrik belirti, Treponema Pallidum

Supporting Institution

yok

Project Number

yok

Thanks

yok

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