Case Report
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Erişkin Dönemde Saptanan Multifokal Epiteliyal Hiperplazi: Nadir İki Olgu Sunumu

Year 2022, Volume: 9 Issue: 1, 236 - 239, 27.04.2022
https://doi.org/10.15311/selcukdentj.837329

Abstract

Multifokal Epiteliyal Hiperplazi nadir görülen asemptomatik benign mukozal bir hastalıktır ve Human Papilloma Virüsün özellikle 13 ve 32 nolu genotipleri ile direkt ilişkilidir.
Sistemik herhangi bir rahatsızlığı olmayan 48 yaşında kadın ve 46 yaşında erkek hasta kliniğimize yaygın tipteki oral lezyonlarının tetkiki amacıyla başvurdu. Klinik muayenede, dil, dudak ve palatal mukozaya yerleşmiş olan lezyonların çok sayıda, ağrısız, düz, pembe renkli, yumuşak karakterde olduğu saptandı. Hastanın anamnezi ve klinik bulgular temel alınarak mukozal lezyonlara yönelik fokal epiteliyal hiperplazisi ön tanısı konuldu. Travma şikayeti bildirilen lezyonlar için eksizyonel biyopsi planlandı. Histopatolojik ve klinik bulgular doğrultusunda oral fokal epitelyal hiperplazi ön tanısı doğrulandı.
Lezyonlar herhangi bir tedavi gerektirmemesine rağmen, hekimler bu tür lezyonlardan haberdar olmalı ve kesin tanı için histopatolojik incelemeyle birlikte dikkatli bir klinik gözlem yapılmalıdır.

References

  • 1. Alberto de Castro L, Gabriel Leite de Castro J, Duarte Lopes da Cruz A, Henrique de Sousa Barbosa B, Spindula-Filho J, Barcelos Costa M. Focal epithelial hyperplasia (heck’s disease) in a 57-year-old Brazilian patient: a case report and literature review. J Clin Med Res 2016; 8(4): 346–50.
  • 2. Said A. Focal epithelial hyperplasia-an update. Oral Pathol Med 2013;42:435–42.
  • 3.Ledesma-Montes C, Garces-Ortiz M and Hernandez-Guerrero JC. Clinicopathological and immunocytochemical study of multifocal epithelial hyperplasia. J Oral Maxillofac Surg 2007;65: 2211-7.
  • 4. Bascones-Martínez S, Cok C. Bascones-Ilundáın S, Arıas-Herrera R, Gomez-Font, Bascones-Ilundáın J. Multifocal epithelial hyperplasia: a potentially precancerous disease? (review). Oncol Lett 2012;3(2): 255–8.
  • 5.Nartey NO, Newman MA, Nyako EA. Focal epithelial hyperplasia: report of six cases from Ghana, West Africa. J Clin Pediatr Dent 2002; 27:63–6.
  • 6.Borborema-Santos CM, Castro MM, Santos PJ, Talhari S, Astolfi-Filho S. Oral focal epithelial hyperplasia: report of five cases. Braz Dent J 2006; 17: 79–82.
  • 7.Morrow DJ, Sandhu HS, Daley TD. Focal epithelial hyperplasia (Heck’s disease) with generalized lesions of the gingiva. A case report. J Periodontol 1993; 64: 63–5.
  • 8.Köse O, Akar A, Safali M, Taştan HB, Kurumlu Z, Gür AR. Focal epithelial hyperplasia treated with interferon alpha-2a. J Dermatolog Treat 2001; 12: 111–3.
  • 9.Ameer AA, Kaliyadan F, Almarzooq YM, Imran M, Alkhars HF. Dermoscopy of focal epithelial hyperplasia. Indian J Dermatol 2020;65(5):429-30.
  • 10.Michael EJ, Husain S, Zalar G, Nuovo G. Focal epithelial hyperplasia in an Ecuadorian girl. Cutis 1999; 64: 395–6.
  • 11.Carlos R, Sedano HO. Multifocal papilloma virus epithelial hyperplasia. Oral Surg Oral Med Oral Pathol 1994; 77: 631–5.
  • 12.Akoğlu G, Metin A, Ceylan GG, Emre S, Akpolat D, Süngü N. Focal epithelial hyperplasia associated with human papillomavirus 13 and common human leukocyte antigen alleles in a Turkish family. Int J Dermatol 2015;54(2):174-8.
  • 13.Ghalayani P, Tavakoli P, Eftekhari M, Haghig MA. Oral focal epithelial hyperplasia: report of three cases. Turk Patoloji Derg 2015, 31:60-3.
  • 14.Al-Maweri S, Al-Soneidar W, Dhaifullah E, Halboub E, Tarakji B. Oral cancer: awareness and knowledge among dental patients in riyadh. J Cancer Educ 2017; 32(2): 308-13.
  • 15.Mansouri Z, Bakhtiari S, and Noormohamadi R. Extensive focal epithelial hyperplasia: a case report. Iran J Pathol 2015; 10(4): 300–5.
Year 2022, Volume: 9 Issue: 1, 236 - 239, 27.04.2022
https://doi.org/10.15311/selcukdentj.837329

Abstract

References

  • 1. Alberto de Castro L, Gabriel Leite de Castro J, Duarte Lopes da Cruz A, Henrique de Sousa Barbosa B, Spindula-Filho J, Barcelos Costa M. Focal epithelial hyperplasia (heck’s disease) in a 57-year-old Brazilian patient: a case report and literature review. J Clin Med Res 2016; 8(4): 346–50.
  • 2. Said A. Focal epithelial hyperplasia-an update. Oral Pathol Med 2013;42:435–42.
  • 3.Ledesma-Montes C, Garces-Ortiz M and Hernandez-Guerrero JC. Clinicopathological and immunocytochemical study of multifocal epithelial hyperplasia. J Oral Maxillofac Surg 2007;65: 2211-7.
  • 4. Bascones-Martínez S, Cok C. Bascones-Ilundáın S, Arıas-Herrera R, Gomez-Font, Bascones-Ilundáın J. Multifocal epithelial hyperplasia: a potentially precancerous disease? (review). Oncol Lett 2012;3(2): 255–8.
  • 5.Nartey NO, Newman MA, Nyako EA. Focal epithelial hyperplasia: report of six cases from Ghana, West Africa. J Clin Pediatr Dent 2002; 27:63–6.
  • 6.Borborema-Santos CM, Castro MM, Santos PJ, Talhari S, Astolfi-Filho S. Oral focal epithelial hyperplasia: report of five cases. Braz Dent J 2006; 17: 79–82.
  • 7.Morrow DJ, Sandhu HS, Daley TD. Focal epithelial hyperplasia (Heck’s disease) with generalized lesions of the gingiva. A case report. J Periodontol 1993; 64: 63–5.
  • 8.Köse O, Akar A, Safali M, Taştan HB, Kurumlu Z, Gür AR. Focal epithelial hyperplasia treated with interferon alpha-2a. J Dermatolog Treat 2001; 12: 111–3.
  • 9.Ameer AA, Kaliyadan F, Almarzooq YM, Imran M, Alkhars HF. Dermoscopy of focal epithelial hyperplasia. Indian J Dermatol 2020;65(5):429-30.
  • 10.Michael EJ, Husain S, Zalar G, Nuovo G. Focal epithelial hyperplasia in an Ecuadorian girl. Cutis 1999; 64: 395–6.
  • 11.Carlos R, Sedano HO. Multifocal papilloma virus epithelial hyperplasia. Oral Surg Oral Med Oral Pathol 1994; 77: 631–5.
  • 12.Akoğlu G, Metin A, Ceylan GG, Emre S, Akpolat D, Süngü N. Focal epithelial hyperplasia associated with human papillomavirus 13 and common human leukocyte antigen alleles in a Turkish family. Int J Dermatol 2015;54(2):174-8.
  • 13.Ghalayani P, Tavakoli P, Eftekhari M, Haghig MA. Oral focal epithelial hyperplasia: report of three cases. Turk Patoloji Derg 2015, 31:60-3.
  • 14.Al-Maweri S, Al-Soneidar W, Dhaifullah E, Halboub E, Tarakji B. Oral cancer: awareness and knowledge among dental patients in riyadh. J Cancer Educ 2017; 32(2): 308-13.
  • 15.Mansouri Z, Bakhtiari S, and Noormohamadi R. Extensive focal epithelial hyperplasia: a case report. Iran J Pathol 2015; 10(4): 300–5.
There are 15 citations in total.

Details

Primary Language Turkish
Subjects Dentistry
Journal Section Case Report
Authors

Ceyda Gürhan 0000-0002-4101-4965

Elif Şener 0000-0003-1402-9392

Umut Aykutlu This is me 0000-0002-9373-0912

Hülya Çankaya This is me 0000-0001-8370-3200

Publication Date April 27, 2022
Submission Date December 10, 2020
Published in Issue Year 2022 Volume: 9 Issue: 1

Cite

Vancouver Gürhan C, Şener E, Aykutlu U, Çankaya H. Erişkin Dönemde Saptanan Multifokal Epiteliyal Hiperplazi: Nadir İki Olgu Sunumu. Selcuk Dent J. 2022;9(1):236-9.