Abstract
Xanthogranulomatous
cholecystitis (XGC) is a benign, rare seen chronic inflammation of gallbladder
as the result of destruction of the mucosa of the gallbladder and infiltration
of macrophages inside the gallbladder wall. It was first described in 1970 as
‘’fibroxanthogranulomatous cholecystitis’’ by Christensen and Ishak. The major
preoperative radiologic finding of XGC is thickening of the gallbladder wall
(>4mm) and its importance lies in the fact that XGC mimics the gallbladder
carcinoma as it does not express a unique finding in either radiologic or
clinical findings, leading to unnecessary enlarged resections due surgeries. The
final diagnosis is usually made during microscopic examination in pathology.
This case report describes clinical, radiologic and pathologic findings of a
patient diagnosed with XGC.
References
- 1. Arcerito M, Moon J, Nguyen KT. Xanthogranulomatous cholecystitis: The great gallbladder carcinoma masquerader. Int J Case Rep Images 2017;8(3):222-226.
- 2. Goldblum JR, Lamps LW, McKenney JK, Myers JL. Gallbladder and Extrahepatic Bile Ducts. In: Lamps LW. Rosai and Ackerman’s Surgical Pathology, Eleventh Edition. Ste. 1800. Philadelphia: 1600 John F. Kennedy Blvd.; 2018. p.844-885.
- 3. Yang T, Zhang BH, Zhang J, Zhang YJ, Jiang XQ, Wu MC. Surgical treatment of xanthogranulomatous cholecystitis: experience in 33 cases. Hepatobiliary Pancreat Dis Int. 2007;6(5):504-508
- 4. Uchiyama K, Ozawa S, Ueno M, Hayami SH, Hirono S, Ina SH, et al. Xanthogranulomatous cholecystitis: the use of preoperative CT findings to differentiate it from gallbladder carcinoma. J Hepatobiliary Pancreat Surg. 2009;16:333-338
- 5. Roberts KM, Parsons MA. Xanthogranulomatous Cholecystitis: clinic-pathological study of 13 cases. J Clin Pathol. 1987;40:412-417.
- 6. Alhomoud H, Abdelmohsen M. Xanthogranulomatous Cholecystitis. World Journal of Laparoscopic Surgery. 2017;10(2):77-79
- 7. Srikanth G, Kumar A, Khare R, Siddappa L, Gupta A, Sikora SS, et al. Should Laparoscopic Cholecystectomy be performed in patients with thick-walled gallbladder? J Hepatobiliary Pancreat Surg. 2004;11:40-44.
- 8. GV Gilberto. Xanthogranulomatous Cholecystitis: 15 years’ Experience. World J. Surg. 2004;28:254-457
Abstract
Ksantogranülomatöz
kolesistit (XGC) ender görülen ve iyi huylu kronik bir safra kesesi
enflamasyonu olup, genelde mukoza zedelenmesi sonrasında makrofajların safra
kesesi duvarına infiltrasyon göstermesi sonucu meydana gelir. İlk olarak 1970
yılında ‘fibroksantogranülomatöz kolesistit’ olarak Christenser ve Ishak
tarafından tanımlanmıştır. Radyolojik olarak safra kesesinde duvar kalınlaşması
(>4 mm) görülmesi nedeniyle, safra kesesi tümörlerini yapı ve morfolojik
görüntüsü ile taklit etmesi açısından tanısı önem taşımaktadır.
XGC'e spesifik bir radyolojik veya klinik bulgu
bulunamadığı için cerrahi işlemler esnasında gereksiz ve genişletilmiş organ
rezeksyonları yapılmaktadır. Kesin tanı patolojide mikroskopik inceleme sonucu
ortaya konur. Bu olgu sunumunda XGC tanısı almış bir
vakanın klinik, radyolojik ve patolojik bulguları sulumuştur.
References
- 1. Arcerito M, Moon J, Nguyen KT. Xanthogranulomatous cholecystitis: The great gallbladder carcinoma masquerader. Int J Case Rep Images 2017;8(3):222-226.
- 2. Goldblum JR, Lamps LW, McKenney JK, Myers JL. Gallbladder and Extrahepatic Bile Ducts. In: Lamps LW. Rosai and Ackerman’s Surgical Pathology, Eleventh Edition. Ste. 1800. Philadelphia: 1600 John F. Kennedy Blvd.; 2018. p.844-885.
- 3. Yang T, Zhang BH, Zhang J, Zhang YJ, Jiang XQ, Wu MC. Surgical treatment of xanthogranulomatous cholecystitis: experience in 33 cases. Hepatobiliary Pancreat Dis Int. 2007;6(5):504-508
- 4. Uchiyama K, Ozawa S, Ueno M, Hayami SH, Hirono S, Ina SH, et al. Xanthogranulomatous cholecystitis: the use of preoperative CT findings to differentiate it from gallbladder carcinoma. J Hepatobiliary Pancreat Surg. 2009;16:333-338
- 5. Roberts KM, Parsons MA. Xanthogranulomatous Cholecystitis: clinic-pathological study of 13 cases. J Clin Pathol. 1987;40:412-417.
- 6. Alhomoud H, Abdelmohsen M. Xanthogranulomatous Cholecystitis. World Journal of Laparoscopic Surgery. 2017;10(2):77-79
- 7. Srikanth G, Kumar A, Khare R, Siddappa L, Gupta A, Sikora SS, et al. Should Laparoscopic Cholecystectomy be performed in patients with thick-walled gallbladder? J Hepatobiliary Pancreat Surg. 2004;11:40-44.
- 8. GV Gilberto. Xanthogranulomatous Cholecystitis: 15 years’ Experience. World J. Surg. 2004;28:254-457
Details
| Primary Language | English |
|---|---|
| Subjects | Health Care Administration |
| Journal Section | Articles |
| Authors | |
| Publication Date | September 16, 2019 |
| Submission Date | February 28, 2019 |
| Published in Issue | Year 2019 Volume: 9 Issue: 3 |
The published articles in SMJ are licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.