Obstrüktif Uyku Apne Sendromlu Hastalarda Optimal Sürekli Pozitif Havayolu Basınç Düzeyini Etkileyen Faktörler

Year 2020, Volume: 10 Issue: 1, 99 - 106, 16.03.2020

Hülya Günbatar , Havva Sayhan Kaplan

https://doi.org/10.31832/smj.678074

Abstract

Öz

Amaç: Bu
çalışmada obstrüktif uyku apne sendromu (OUAS) olan hastalarda optimal CPAP
düzeylerini etkileyen faktörlerin (VKİ, boyun çevresi, AHİ vb.) araştırılılması
amaçlandı.

Gereç
ve Yöntem: Bu çalışmaya CPAP tedavisi için başarılı oto titrasyon
uygulanan 120 OUAS hastası dahil edildi. Optimal CPAP seviyesi ile başlangıç
​​verileri arasındaki korelasyonlar analiz edildi.

Bulgular: 120
OUAS hastasında ortalama optimal basınç seviyesi 9.11 ± 2.81 cm H₂O
idi. Hafif, orta ve şiddetli OUAS gruplarında ortalama optimal basınç seviyeleri
sırasıyla 8.01 ± 2.60, 8.32 ± 2.22 ve 9.71 ± 3.01 cm H₂O idi. Apne /
hipopne indeksi (AHI) (r = 0.297, p <0.001) ve minimal SaO₂ (r =
-0.264, p <0.004) optimal basınç seviyesi ile anlamlı korelasyon gösterdi.
Titrasyon yetmezliği grubundaki 22 hastada genel olarak ağır AHI vardı; 6
hastada REM ilişkili, 2 hastada pozisyona bağlı OUAS mevcuttu. Titrasyon
yetmezliği grubunda, belirli bir tanısı (hızlı göz hareketi (REM) veya pozisyon
OUAS) bulunmayan hastalarda çok ciddi AHI düzeyleri vardı (ortalama AHI 67.90
idi).

Sonuç: Korelasyon
testlerine göre optimal CPAP seviyesinin en önemli iki belirleyicisi AHI ve en
düşük saturasyon olarak bulundu.

Keywords

Obstrüktif uyku apne sendromu, Sürekli pozitif havayolu basıncı, apne, Polisomnografi

Factors Affecting Optimal Continuous Positive Airway Pressure Level in Patients with Obstructive Sleep Apnea Syndrome

Abstract

Abstract

Objectives: This
study aimed to examine factors (BMI, neck circumference, AHI etc.) affecting
optimal CPAP levels in patients with obstructive sleep apnea syndrome (OSAS).

Materials
and Methods: A total of 120 patients with OSAS who
underwent successful auto-titration for CPAP treatment were included in this
study. Correlations between the optimal CPAP level and baseline data were
analyzed.

Results: The
mean optimal pressure level in the 120 OSAS patients was 9.11 ± 2.81 cm H₂O.
The mean optimal pressure levels in the mild, moderate, and severe OSAS groups were
8.01 ± 2.60, 8.32 ± 2.22, and 9.71 ± 3.01 cm H₂O, respectively.
Apnea/hypopnea index (AHI) (r=0.297, p<0.001) and minimal SaO₂
(r=-0.264, p<0.004) were significantly correlated with optimal pressure
level. 22 patients in the titration failure group had severe AHI overall; 6
patients had REM-related and 2 had position-related OSAS. Patients in the titration
failure group who did not have a specific diagnosis (rapid eye movement (REM)
or positional OSAS) had very severe AHI levels (mean AHI of 67.90).

Conclusion: According
to the correlation tests, AHI and the lowest saturation were the two most
important predictors of optimal CPAP level.

Keywords

Obstructive sleep apnea syndrome, Continuous positive airway pressure, apnea, polysomnography

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